U.S. flag

An official website of the United States government

cnga1a cyclic nucleotide gated channel subunit alpha 1a [ Danio rerio (zebrafish) ]

Gene ID: 100001558, updated on 9-Dec-2024

Summary

Official Symbol
cnga1aprovided by ZNC
Official Full Name
cyclic nucleotide gated channel subunit alpha 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-090312-66
See related
Ensembl:ENSDARG00000029898 AllianceGenome:ZFIN:ZDB-GENE-090312-66
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-22i16.2
Summary
Predicted to enable cGMP binding activity; intracellularly cAMP-activated cation channel activity; and intracellularly cGMP-activated cation channel activity. Predicted to be involved in monoatomic cation transmembrane transport. Predicted to act upstream of or within monoatomic ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of intracellular cyclic nucleotide activated cation channel complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 49. Orthologous to human CNGA1 (cyclic nucleotide gated channel subunit alpha 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See cnga1a in Genome Data Viewer
Location:
chromosome: 1
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (43894525..43899422, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (43193361..43198258, complement)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene 3-hydroxybutyrate dehydrogenase, type 2 Neighboring gene tachykinin receptor 3a Neighboring gene enamelin Neighboring gene secretory calcium-binding phosphoprotein 5

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cGMP binding  
enables intracellularly cAMP-activated cation channel activity  
enables intracellularly cGMP-activated cation channel activity  
enables monoatomic ion channel activity  
enables protein-containing complex binding  
Component Evidence Code Pubs
part_of intracellular cyclic nucleotide activated cation channel complex  
located_in membrane  
is_active_in plasma membrane  

General protein information

Preferred Names
cyclic nucleotide gated channel subunit alpha 1a
Names
cyclic nucleotide gated channel alpha 1a

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145623.1NP_001139095.1  cyclic nucleotide gated channel subunit alpha 1a

    Status: PROVISIONAL

    Source sequence(s)
    CR385050
    UniProtKB/TrEMBL
    A0A8M1NTF4, B8JHY6, E9QFG9
    Related
    ENSDARP00000115254.2, ENSDART00000134649.4
    Conserved Domains (4) summary
    COG0664
    Location:447601
    Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
    cd00038
    Location:453569
    CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
    pfam00520
    Location:168381
    Ion_trans; Ion transport protein
    pfam16526
    Location:569625
    CLZ; C-terminal leucine zipper domain of cyclic nucleotide-gated channels

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    43894525..43899422 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
External link. Please review our privacy policy.