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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog
Summary
- Gene Symbol
-
- grin2a.L
- Organism
- Xenopus laevis (African clawed frog)
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cell membrane
- Disulfide bond
- Glycoprotein
- Ligand-gated ion channel
- Magnesium
- Metal-binding
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Zinc
- Proteins
| UniProt | Protein Name |
|---|---|
| B7ZSK1 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| excitatory postsynaptic potential | ||
| ion transmembrane transport | ||
| calcium ion transmembrane import into cytosol | ||
| response to zinc ion | ||
| monoatomic ion transport |
GO Hierarchy
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| ligand-gated monoatomic ion channel activity | ||
| glutamate-gated calcium ion channel activity | ||
| NMDA glutamate receptor activity | ||
| metal ion binding | ||
| glutamate-gated receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ligand-gated monoatomic ion channel activity |
| monoatomic ion transport |
| InterPro |
|---|
| Periplasmic binding protein-like I |
| Receptor, ligand binding region |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050741 | alcohol dependence | |
| DOID:10652 | Alzheimer's disease | |
| DOID:11206 | opioid abuse | |
| DOID:12858 | Huntington's disease | |
| DOID:3312 | bipolar disorder | |
| DOID:5419 | schizophrenia | |
| DOID:8725 | vascular dementia | |
| DOID:9256 | colorectal cancer | |
| DOID:9261 | nasopharynx carcinoma | |
| DOID:9976 | heroin dependence |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 2903 | 9606_0:0038d7 | HGNC:4585 | ||
| 2904 | 9606_0:000c96 | |||
| 417965 | 9031_0:0004e0 | |||
| 427678 | 9031_0:002ccc | |||
| 490012 | 9615_0:0016bd | |||
| 494009 | 9615_0:004153 | |||
| 524212 | 9913_0:00487c | |||
| 537804 | 9913_0:000fc1 | |||
| 698571 | 9544_0:002d85 | |||
| 751956 | 59729_0:0007ac |
