U.S. flag

An official website of the United States government

F8 coagulation factor VIII [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100174452, updated on 3-Dec-2024

Summary

Gene symbol
F8
Gene description
coagulation factor VIII
Locus tag
CR201_G0049972
See related
Ensembl:ENSPPYG00000020895
Gene type
protein coding
RefSeq status
MODEL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
chromosome: X
Exon count:
28
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) X NC_072008.2 (161333890..161553381, complement)
RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) X NC_072008.1 (161333917..161557019, complement)

Chromosome X - NC_072008.2Genomic Context describing neighboring genes Neighboring gene non-histone chromosomal protein HMG-14-like Neighboring gene small integral membrane protein 9 Neighboring gene histone H2A-Bbd type 2/3 Neighboring gene coagulation factor VIII associated 1 Neighboring gene FUN14 domain containing 2 Neighboring gene mature T cell proliferation 1 Neighboring gene C-X9-C motif containing 4

Genomic regions, transcripts, and products

General gene information

Clone Names

  • DKFZp459D2216

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables copper ion binding PubMed 
enables oxidoreductase activity PubMed 
enables signaling receptor activity PubMed 
Component Evidence Code Pubs
located_in plasma membrane PubMed 

General protein information

Preferred Names
coagulation factor VIII
Names
coagulation factor VIII, procoagulant component

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

  1. NC_072008.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Range
    161333890..161553381 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024240562.3XP_024096330.1  coagulation factor VIII isoform X2

    UniProtKB/TrEMBL
    A0A2J8RMD1, A0A8I5YK92, Q5RAM1
    Related
    ENSPPYP00000028171.1
    Conserved Domains (2) summary
    cd00057
    Location:60209
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
    cl25480
    Location:452
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
  2. XM_054545278.2XP_054401253.1  coagulation factor VIII isoform X1

    UniProtKB/TrEMBL
    Q5RAM1
  3. XM_024240561.3XP_024096329.1  coagulation factor VIII isoform X3

    UniProtKB/TrEMBL
    A0A2J8RM48, H2PXB0
    Related
    ENSPPYP00000023391.3
    Conserved Domains (7) summary
    cd00057
    Location:21952344
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
    cd04227
    Location:399575
    CuRO_3_FVIII_like; The third cupredoxin domain of coagulation factor VIII and similar proteins
    cd04228
    Location:17141880
    CuRO_5_FVIII_like; The fifth cupredoxin domain of coagulation factor VIII and similar proteins
    cd11015
    Location:211345
    CuRO_2_FVIII_like; The second cupredoxin domain of coagulation factor VIII and similar proteins
    cd11016
    Location:588730
    CuRO_4_FVIII_like; The fourth cupredoxin domain of coagulation factor VIII and similar proteins
    cd11018
    Location:18922035
    CuRO_6_FVIII_like; The sixth cupredoxin domain of coagulation factor VIII and similar proteins
    cd14452
    Location:22201
    CuRO_1_FVIII_like; The first cupredoxin domain of coagulation factor VIII and similar proteins
External link. Please review our privacy policy.