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phosphogluconate dehydrogenase

Summary

Gene Symbol

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

100360180

PubChem

100360180

Alliance of Genome Resources

RGD:1583832

Annotation

Keyword

Acetylation
Cytoplasm
Gluconate utilization
NADP
Oxidoreductase
Pentose shunt
Phosphoprotein
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P85968
A6IUA3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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2

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GO Term	Evidence Code	PMID
D-gluconate catabolic process	IBA
D-gluconate metabolic process	IDA IEA	17447164
NADP metabolic process	IDA	6813321
pentose biosynthetic process	ISO
pentose-phosphate shunt, oxidative branch	IBA IMP ISO	9794092

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

biosynthetic process [inference]

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

pentose biosynthetic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

pentose biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

aldonic acid metabolic process [inference]

D-gluconate metabolic process

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

generation of precursor metabolites and energy [inference]

NADPH regeneration [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

glucose 6-phosphate metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

glucose 6-phosphate metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

pentose metabolic process [inference]

pentose biosynthetic process

monosaccharide biosynthetic process [inference]

pentose biosynthetic process

oligosaccharide metabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

D-gluconate metabolic process

D-gluconate catabolic process

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

pentose biosynthetic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

aldonic acid metabolic process [inference]

D-gluconate metabolic process

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

pentose metabolic process [inference]

pentose biosynthetic process

monosaccharide biosynthetic process [inference]

pentose biosynthetic process

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

aldonic acid metabolic process [inference]

D-gluconate metabolic process

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

small molecule biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

pentose biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

pentose metabolic process [inference]

pentose biosynthetic process

monosaccharide biosynthetic process [inference]

pentose biosynthetic process

oligosaccharide metabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

D-gluconate metabolic process

D-gluconate catabolic process

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

pentose biosynthetic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

aldonic acid metabolic process [inference]

D-gluconate metabolic process

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

aldonic acid metabolic process [inference]

D-gluconate metabolic process

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

glucose 6-phosphate metabolic process [inference]

carbohydrate derivative metabolic process [inference]

glucose 6-phosphate metabolic process [inference]

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

oligosaccharide catabolic process [inference]

D-gluconate catabolic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

pentose biosynthetic process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

aldonic acid metabolic process [inference]

D-gluconate metabolic process

D-gluconate catabolic process

aldonic acid catabolic process [inference]

D-gluconate catabolic process

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

generation of precursor metabolites and energy [inference]

NADPH regeneration [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

glucose 6-phosphate metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

glucose 6-phosphate metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

aldonic acid catabolic process [inference]

D-gluconate catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process

NADPH regeneration [inference]

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
FANCM-MHF complex	IEA
cytosol	IBA ISO
axon	IEA
microtubule	IEA
synapse	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

FANCM-MHF complex

cellular anatomical entity [inference]

cytosol

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
carboxylic acid binding	IDA	17447164 2843500
microtubule motor activity	IEA
phosphogluconate dehydrogenase (decarboxylating) activity	IBA IDA IEA ISO ISS	17447164 21930213 2843500 6813321
microtubule binding	IEA
phosphogluconate 2-dehydrogenase activity

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microtubule motor activity

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

binding [inference]

protein binding [inference]

cytoskeletal protein binding [inference]

tubulin binding [inference]

microtubule binding

protein dimerization activity [inference]

protein heterodimerization activity

carbohydrate binding

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

NADP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

NADP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

microtubule motor activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **21 - 30** of 78 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mandrillus leucophaeus	105551419		MANLE13097
Gorilla gorilla gorilla	101151108		GORGO17380
Pan paniscus	100985461		PANPA00263
Pan troglodytes	100534605		PANTR19893
Pongo abelii	100461195		PONAB17833
Homo sapiens	23095		HUMAN47374
Homo sapiens	5226	HGNC:8891
Canis lupus familiaris	479605		CANLF15827
Ursus americanus	123779086		URSAM06401
Ailuropoda melanoleuca	100478514		AILME04353

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