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aldo-keto reductase family 1 member A1

Summary

Gene Symbol

Akr1a1

Organism

Cricetulus griseus (Chinese hamster)

External Links

NCBI Gene: 100689106
PubChem: 100689106

Annotation

Keyword

Acetylation
Cell membrane
Cytoplasm
Lipid metabolism
NADP
Oxidoreductase
Phosphoprotein
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
G3GYP7	Alcohol dehydrogenase [NADP(+)] Aldehyde reductase Glucuronate reductase Glucuronolactone reductase S-nitroso-CoA reductase
O70473	Alcohol dehydrogenase [NADP(+)] Aldehyde reductase Glucuronate reductase Glucuronolactone reductase S-nitroso-CoA reductase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 8** of 8 in total

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GO Term	Evidence Code	PMID
doxorubicin metabolic process
L-ascorbic acid biosynthetic process
glucuronate catabolic process to xylulose 5-phosphate

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

aldehyde catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

aldehyde catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organophosphate biosynthetic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

glucuronate catabolic process to xylulose 5-phosphate

carbohydrate derivative biosynthetic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

glucuronate catabolic process to xylulose 5-phosphate

organic cyclic compound biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

secondary metabolic process [inference]

polyketide metabolic process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

aldehyde catabolic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate metabolic process [inference]

D-glucuronate catabolic process

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

cellular aromatic compound metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

xylulose 5-phosphate metabolic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

glucuronate catabolic process to xylulose 5-phosphate

organophosphate metabolic process [inference]

xylulose 5-phosphate metabolic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

glucuronate catabolic process to xylulose 5-phosphate

organophosphate biosynthetic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

glucuronate catabolic process to xylulose 5-phosphate

cellular ketone metabolic process [inference]

quinone metabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

aldehyde catabolic process

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

lactone metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

lipid metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

doxorubicin metabolic process

tertiary alcohol metabolic process [inference]

doxorubicin metabolic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate metabolic process [inference]

D-glucuronate catabolic process

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular ketone metabolic process [inference]

quinone metabolic process [inference]

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular aldehyde metabolic process [inference]

aldehyde catabolic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate metabolic process [inference]

D-glucuronate catabolic process

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

lipid metabolic process

organophosphate metabolic process [inference]

xylulose 5-phosphate metabolic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

glucuronate catabolic process to xylulose 5-phosphate

organophosphate biosynthetic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

glucuronate catabolic process to xylulose 5-phosphate

polyketide metabolic process [inference]

cellular ketone metabolic process [inference]

quinone metabolic process [inference]

carbohydrate derivative metabolic process [inference]

xylulose 5-phosphate metabolic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

glucuronate catabolic process to xylulose 5-phosphate

carbohydrate derivative biosynthetic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

glucuronate catabolic process to xylulose 5-phosphate

glycosyl compound metabolic process [inference]

glycoside metabolic process [inference]

aminoglycoside antibiotic metabolic process [inference]

daunorubicin metabolic process

doxorubicin metabolic process

organic cyclic compound metabolic process [inference]

lactone metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic cyclic compound biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

aldehyde catabolic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

monosaccharide biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organophosphate biosynthetic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

glucuronate catabolic process to xylulose 5-phosphate

carbohydrate derivative biosynthetic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

glucuronate catabolic process to xylulose 5-phosphate

organic cyclic compound biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

doxorubicin metabolic process

tertiary alcohol metabolic process [inference]

doxorubicin metabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

aldehyde catabolic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

glucuronate catabolic process [inference]

D-glucuronate metabolic process [inference]

D-glucuronate catabolic process

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

cellular aromatic compound metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

xylulose 5-phosphate metabolic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

glucuronate catabolic process to xylulose 5-phosphate

organophosphate metabolic process [inference]

xylulose 5-phosphate metabolic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

glucuronate catabolic process to xylulose 5-phosphate

organophosphate biosynthetic process [inference]

xylulose 5-phosphate biosynthetic process [inference]

glucuronate catabolic process to xylulose 5-phosphate

cellular ketone metabolic process [inference]

quinone metabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

monocarboxylic acid catabolic process [inference]

glucuronate catabolic process [inference]

aldehyde catabolic process

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

L-ascorbic acid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

lactone metabolic process [inference]

L-ascorbic acid metabolic process [inference]

L-ascorbic acid biosynthetic process

lactone biosynthetic process [inference]

L-ascorbic acid biosynthetic process

cellular detoxification [inference]

cellular detoxification of aldehyde

detoxification [inference]

cellular detoxification [inference]

cellular detoxification of aldehyde

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cytosol	IEA	30032202
synapse
apical plasma membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane [inference]

plasma membrane region [inference]

apical plasma membrane

cell junction [inference]

synapse

Displaying entries **6 - 7** of 7 in total

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GO Term	Evidence Code	PMID
glucuronolactone reductase activity
S-nitrosoglutathione reductase activity

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

aldo-keto reductase (NADP) activity [inference]

alcohol dehydrogenase (NADP+) activity [inference]

alditol:NADP+ 1-oxidoreductase activity

alcohol dehydrogenase [NAD(P)+] activity [inference]

alcohol dehydrogenase (NAD+) activity [inference]

S-nitrosoglutathione reductase activity

S-(hydroxymethyl)glutathione dehydrogenase activity [inference]

S-nitrosoglutathione reductase activity

methylglyoxal reductase (NADPH-dependent, acetol producing)

glycerol dehydrogenase [NAD(P)+] activity [inference]

glycerol dehydrogenase [NADP+] activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **31 - 40** of 88 in total

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Species	Gene ID	Orthologous MAtrix
Pan troglodytes	741418	PANTR20948
Pongo abelii	100173796	PONAB20048
Homo sapiens	10327	HUMAN49596
Canis lupus familiaris	610537	CANLF04072
Vulpes vulpes	112914782	VULVU06309
Ursus americanus	123793759	URSAM24001
Ailuropoda melanoleuca	100466911	AILME12536
Mustela putorius furo	101688596	MUSPF18170
Felis catus	101091464	FELCA21334
Panthera leo	122226923	PANLE10116

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