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CLCN3 chloride voltage-gated channel 3 [ Serinus canaria (Common canary) ]

Gene ID: 103825926, updated on 12-Aug-2024

Summary

Gene symbol
CLCN3
Gene description
chloride voltage-gated channel 3
See related
EnsemblRapid:ENSSCAG00000010271
Gene type
protein coding
RefSeq status
MODEL
Organism
Serinus canaria
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Passeroidea; Fringillidae; Carduelinae; Serinus
Orthologs
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Genomic context

See CLCN3 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2023_02 current serCan2020 (GCF_022539315.1) 4 NC_066317.1 (34306689..34367574)

Chromosome 4 - NC_066317.1Genomic Context describing neighboring genes Neighboring gene carbonyl reductase 4 Neighboring gene SH3 domain containing ring finger 1 Neighboring gene NIMA related kinase 1 Neighboring gene histone PARylation factor 1 Neighboring gene microfibril associated protein 3 like

Genomic regions, transcripts, and products

Genomic Sequence:
NC_066317.1 Chromosome 4 Reference serCan2020 Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Component Evidence Code Pubs
located_in Golgi apparatus PubMed 
located_in early endosome PubMed 
located_in membrane PubMed 
located_in synaptic vesicle PubMed 

General protein information

Preferred Names
H(+)/Cl(-) exchange transporter 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_022539315.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference serCan2020 Primary Assembly

Genomic

  1. NC_066317.1 Reference serCan2020 Primary Assembly

    Range
    34306689..34367574
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030239035.2XP_030094895.1  H(+)/Cl(-) exchange transporter 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C9UDK4
    Conserved Domains (2) summary
    cd03684
    Location:136642
    ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
    cd04591
    Location:653803
    CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria
  2. XM_030239034.2XP_030094894.1  H(+)/Cl(-) exchange transporter 3 isoform X1

    UniProtKB/TrEMBL
    A0A8C9UDK4
    Related
    ENSSCAP00000013924.1, ENSSCAT00000015622.2
    Conserved Domains (2) summary
    cd03684
    Location:136642
    ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
    cd04591
    Location:653803
    CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria
  3. XM_030239036.2XP_030094896.1  H(+)/Cl(-) exchange transporter 3 isoform X3

    Related
    ENSSCAP00000031826.1, ENSSCAT00000034820.1
    Conserved Domains (2) summary
    cd03684
    Location:136642
    ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
    cd04591
    Location:653803
    CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria
  4. XM_009101155.4XP_009099403.1  H(+)/Cl(-) exchange transporter 3 isoform X1

    See identical proteins and their annotated locations for XP_009099403.1

    UniProtKB/TrEMBL
    A0A8C9UDK4
    Conserved Domains (2) summary
    cd03684
    Location:136642
    ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
    cd04591
    Location:653803
    CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria
  5. XM_009101156.4XP_009099404.1  H(+)/Cl(-) exchange transporter 3 isoform X2

    See identical proteins and their annotated locations for XP_009099404.1

    UniProtKB/TrEMBL
    A0A8C9UE33
    Related
    ENSSCAP00000013925.1, ENSSCAT00000015623.2
    Conserved Domains (2) summary
    cd03684
    Location:110616
    ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
    cd04591
    Location:627777
    CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria
  6. XM_009101158.4XP_009099406.1  H(+)/Cl(-) exchange transporter 3 isoform X4

    See identical proteins and their annotated locations for XP_009099406.1

    Conserved Domains (2) summary
    cd03684
    Location:110616
    ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
    cd04591
    Location:627777
    CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria
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