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hydroxysteroid 17-beta dehydrogenase 1

Summary

Gene Symbol

HSD17B1

Organism

Cercocebus atys (sooty mangabey)

External Links

NCBI Gene: 105579672
KEGG Gene ID: caty:105579672
PubChem: 105579672

Annotation

Keyword

Cytoplasm
Oxidoreductase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A2K5LEF1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
estrogen biosynthetic process	IEA	22301074

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

hormone biosynthetic process [inference]

estrogen biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

hormone metabolic process [inference]

estrogen metabolic process [inference]

estrogen biosynthetic process

hormone biosynthetic process [inference]

estrogen biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

estrogen metabolic process [inference]

estrogen biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

estrogen metabolic process [inference]

estrogen biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

estrogen metabolic process [inference]

estrogen biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

steroid hormone biosynthetic process [inference]

estrogen biosynthetic process

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

estrogen metabolic process [inference]

estrogen biosynthetic process

hormone biosynthetic process [inference]

estrogen biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
cytoplasm	IEA	22301074

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

Displaying 1 entry
GO Term	Evidence Code	PMID
estradiol 17-beta-dehydrogenase [NAD(P)] activity	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

steroid dehydrogenase activity [inference]

steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

estradiol 17-beta-dehydrogenase [NAD(P)] activity

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

estradiol 17-beta-dehydrogenase [NAD(P)] activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00044

Name

17beta-estradiol 17-dehydrogenase [EC:1.1.1.62]

References

Rhea

17β-estradiol + NADP⁺

H⁺ + estrone + NADPH

Enzyme

1.1.1.62

PMID

17β-estradiol + NAD⁺

H⁺ + estrone + NADH

Enzyme

1.1.1.62

PMID

Ortholog

Displaying entries **41 - 50** of 69 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	15485		MOUSE04210
Rattus norvegicus	25322		RATNO03531
Cavia porcellus	100718199		CAVPO17610
Octodon degus	101574253		OCTDE12637
Monodelphis domestica	100011776		MONDO10518
Vombatus ursinus	114049234		VOMUR18400
Bos indicus x Bos taurus	113877368		BOBOX13590
Otolemur garnettii	100956146		OTOGA14994
Takifugu rubripes	101070121		TAKRU41078
Chinchilla lanigera	102019459		CHILA12722

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.0.0

Last updated: August 19, 2024