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Braf transforming gene
Summary
- Gene Symbol
-
- Braf
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Acetylation
- Allosteric enzyme
- Alternative splicing
- Cell membrane
- Chromosomal rearrangement
- Cytoplasm
- Isopeptide bond
- Metal-binding
- Methylation
- Nucleus
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- Serine/threonine-protein kinase
- Ubl conjugation
- Zinc
- Proteins
| UniProt | Protein Name |
|---|---|
| P28028 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of gene expression | ||
| stress fiber assembly | ||
| positive regulation of ERK1 and ERK2 cascade | ||
| positive regulation of substrate adhesion-dependent cell spreading | ||
| endothelial cell apoptotic process |
GO Hierarchy
- regulation of cell population proliferation
biological process
metabolic process
cellular process [inference]
multicellular organismal process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular process [inference]
regulation of cellular component organization [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitochondrion |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| kinase activity | ||
| MAP kinase kinase kinase activity | ||
| small GTPase binding | ||
| catalytic activity | ||
| transferase activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050700 | cardiomyopathy | |
| DOID:0050861 | colorectal adenocarcinoma | |
| DOID:0060233 | cardiofaciocutaneous syndrome | |
| DOID:0060585 | Noonan syndrome 7 | |
| DOID:0080550 | Noonan syndrome with multiple lentigines 3 | |
| DOID:0111460 | cardiofaciocutaneous syndrome 1 | |
| DOID:1324 | lung cancer | |
| DOID:1520 | colon carcinoma | |
| DOID:162 | cancer | |
| DOID:1793 | pancreatic cancer |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 102018105 | CHILA20216 | ||
| 110216339 | PHACI08404 | ||
| 101052142 | SAIBB16442 | ||
| 117018062 | RHIFE12265 | ||
| 100219601 | TAEGU08868 | ||
| 101806469 | FICAL10672 | ||
| 108541537 | RHIBE22036 | ||
| 104659700 | RHIRO26482 | ||
| 100582848 | NOMLE07523 | ||
| 107560707 | SINGR69319 |
