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histamine N-methyltransferase

Summary

Gene Symbol

Hnmt

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

140483

PubChem

140483

Alliance of Genome Resources

MGI:2153181

Annotation

Keyword

Cytoplasm
Methyltransferase
Reference proteome
S-adenosyl-L-methionine

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A2AQK4
Q91VF2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
response to immobilization stress	IEA
response to tumor cell	IEA
response to glucocorticoid	IEA
response to amine	IEA
histamine catabolic process	ISO ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound catabolic process [inference]

imidazole-containing compound catabolic process [inference]

histamine catabolic process

imidazole-containing compound metabolic process [inference]

histamine metabolic process

histamine catabolic process

imidazole-containing compound catabolic process [inference]

histamine catabolic process

ammonium ion metabolic process [inference]

histamine metabolic process

histamine catabolic process

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

histamine metabolic process

histamine catabolic process

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

histamine catabolic process

imidazole-containing compound metabolic process [inference]

histamine metabolic process

histamine catabolic process

imidazole-containing compound catabolic process [inference]

histamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

histamine catabolic process

imidazole-containing compound catabolic process [inference]

histamine catabolic process

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

imidazole-containing compound catabolic process [inference]

histamine catabolic process

cellular nitrogen compound catabolic process [inference]

imidazole-containing compound catabolic process [inference]

histamine catabolic process

heterocycle catabolic process [inference]

imidazole-containing compound catabolic process [inference]

histamine catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

imidazole-containing compound catabolic process [inference]

histamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

histamine catabolic process

imidazole-containing compound catabolic process [inference]

histamine catabolic process

methylation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

aromatic compound catabolic process [inference]

imidazole-containing compound catabolic process [inference]

histamine catabolic process

imidazole-containing compound metabolic process [inference]

histamine metabolic process

histamine catabolic process

imidazole-containing compound catabolic process [inference]

histamine catabolic process

sulfur compound metabolic process [inference]

S-adenosylmethionine metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

histamine metabolic process

histamine catabolic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound catabolic process [inference]

imidazole-containing compound catabolic process [inference]

histamine catabolic process

imidazole-containing compound metabolic process [inference]

histamine metabolic process

histamine catabolic process

imidazole-containing compound catabolic process [inference]

histamine catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

imidazole-containing compound catabolic process [inference]

histamine catabolic process

cellular nitrogen compound catabolic process [inference]

imidazole-containing compound catabolic process [inference]

histamine catabolic process

heterocycle catabolic process [inference]

imidazole-containing compound catabolic process [inference]

histamine catabolic process

heterocycle metabolic process [inference]

heterocycle catabolic process [inference]

imidazole-containing compound catabolic process [inference]

histamine catabolic process

imidazole-containing compound metabolic process [inference]

histamine metabolic process

histamine catabolic process

imidazole-containing compound catabolic process [inference]

histamine catabolic process

organic substance metabolic process [inference]

S-adenosylmethionine metabolic process

organic cyclic compound metabolic process [inference]

imidazole-containing compound metabolic process [inference]

histamine metabolic process

histamine catabolic process

imidazole-containing compound catabolic process [inference]

histamine catabolic process

organic cyclic compound catabolic process [inference]

imidazole-containing compound catabolic process [inference]

histamine catabolic process

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

histamine metabolic process

histamine catabolic process

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

histamine catabolic process

imidazole-containing compound metabolic process [inference]

histamine metabolic process

histamine catabolic process

imidazole-containing compound catabolic process [inference]

histamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

histamine catabolic process

imidazole-containing compound catabolic process [inference]

histamine catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

imidazole-containing compound catabolic process [inference]

histamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

histamine catabolic process

imidazole-containing compound catabolic process [inference]

histamine catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

aromatic compound catabolic process [inference]

imidazole-containing compound catabolic process [inference]

histamine catabolic process

imidazole-containing compound metabolic process [inference]

histamine metabolic process

histamine catabolic process

imidazole-containing compound catabolic process [inference]

histamine catabolic process

sulfur compound metabolic process [inference]

S-adenosylmethionine metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

histamine metabolic process

histamine catabolic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound catabolic process [inference]

imidazole-containing compound catabolic process [inference]

histamine catabolic process

imidazole-containing compound metabolic process [inference]

histamine metabolic process

histamine catabolic process

imidazole-containing compound catabolic process [inference]

histamine catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

imidazole-containing compound catabolic process [inference]

histamine catabolic process

cellular nitrogen compound catabolic process [inference]

imidazole-containing compound catabolic process [inference]

histamine catabolic process

heterocycle catabolic process [inference]

imidazole-containing compound catabolic process [inference]

histamine catabolic process

heterocycle metabolic process [inference]

heterocycle catabolic process [inference]

imidazole-containing compound catabolic process [inference]

histamine catabolic process

imidazole-containing compound metabolic process [inference]

histamine metabolic process

histamine catabolic process

imidazole-containing compound catabolic process [inference]

histamine catabolic process

response to stimulus [inference]

response to stress [inference]

response to osmotic stress [inference]

hyperosmotic response

response to immobilization stress

response to biotic stimulus [inference]

response to tumor cell

response to abiotic stimulus [inference]

response to osmotic stress [inference]

hyperosmotic response

response to endogenous stimulus [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to organonitrogen compound [inference]

response to amine

response to alkaloid [inference]

response to cocaine

response to organic cyclic compound [inference]

response to cocaine

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to lipid [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to cytokine [inference]

response to interleukin-1

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to amine

response to alkaloid [inference]

response to cocaine

response to oxygen-containing compound [inference]

response to cocaine

response to salt [inference]

response to cocaine

Displaying **all 4** entries
GO Term	Evidence Code	PMID
nucleoplasm	IEA ISO
centrosome	IEA ISO
cytosol	IEA ISO
cytoplasm	ISO ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

cytosol

Displaying **all 2** entries
GO Term	Evidence Code	PMID
histamine N-methyltransferase activity	ISO ISS
N-methyltransferase activity	IDA	11475331

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity [inference]

N-methyltransferase activity

histamine N-methyltransferase activity

S-adenosylmethionine-dependent methyltransferase activity [inference]

histamine N-methyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

histamine N-methyltransferase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
I: Lipid transport and metabolism

Displaying **all 3** entries
Gene Ontology
N-methyltransferase activity
histamine N-methyltransferase activity
methylation

Displaying **all 2** entries
InterPro
Histamine N-methyltransferase-like
S-adenosyl-L-methionine-dependent methyltransferase superfamily

Disease

Disease Ontology

Displaying **all 10** entries
DO ID	Disease Name	Source
DOID:0081214	autosomal recessive intellectual developmental disorder 51	Alliance of Genome Resources
DOID:11870	Pick's disease	Alliance of Genome Resources
DOID:12858	Huntington's disease	Alliance of Genome Resources
DOID:14250	Down syndrome	Alliance of Genome Resources
DOID:14330	Parkinson's disease	Alliance of Genome Resources
DOID:2841	asthma	Alliance of Genome Resources
DOID:3310	atopic dermatitis	Alliance of Genome Resources
DOID:3454	brain infarction	Alliance of Genome Resources
DOID:4990	essential tremor	Alliance of Genome Resources
DOID:8577	ulcerative colitis	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **103** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	3176		HGNC:5028	HUMAN64861
Rattus norvegicus	81676	10116_1:001653	RGD:71049	RATNO27859
Danio rerio	445242		ZFIN:ZDB-GENE-040801-157
Canis lupus familiaris	476133			CANLF06385
Bos taurus	613413			BOVIN24345
Macaca mulatta	703857			MACMU06971
Macaca mulatta	706713			MACMU06971
Pan troglodytes	742204			PANTR28764
Xenopus tropicalis	779808		Xenbase:XB-GENE-1001069
Equus caballus	100051119			HORSE13318

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024