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cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)

Summary

Gene Symbol

CYP2D7

Organism

Homo sapiens (human)

External Links

NCBI Gene

1564

PubChem

1564

Alliance of Genome Resources

HGNC:2624

Annotation

Keyword

Cytoplasm
Glycoprotein
Heme
Mitochondrion
Monooxygenase
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A0A087X1C5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
xenobiotic metabolic process	IDA	15051713 18838503
xenobiotic metabolic process	IBA
arachidonic acid metabolic process	IBA
xenobiotic catabolic process	IDA	15051713 18838503

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

xenobiotic catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

arachidonic acid metabolic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

long-chain fatty acid metabolic process [inference]

arachidonic acid metabolic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process

xenobiotic metabolic process

xenobiotic catabolic process

cellular catabolic process [inference]

xenobiotic catabolic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

long-chain fatty acid metabolic process [inference]

arachidonic acid metabolic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

long-chain fatty acid metabolic process [inference]

arachidonic acid metabolic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

arachidonic acid metabolic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

long-chain fatty acid metabolic process [inference]

arachidonic acid metabolic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

arachidonic acid metabolic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

long-chain fatty acid metabolic process [inference]

arachidonic acid metabolic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

long-chain fatty acid metabolic process [inference]

arachidonic acid metabolic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process

olefinic compound metabolic process [inference]

arachidonic acid metabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

arachidonic acid metabolic process

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

long-chain fatty acid metabolic process [inference]

arachidonic acid metabolic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process

xenobiotic metabolic process

xenobiotic catabolic process

cellular catabolic process [inference]

xenobiotic catabolic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

long-chain fatty acid metabolic process [inference]

arachidonic acid metabolic process

unsaturated fatty acid metabolic process [inference]

arachidonic acid metabolic process

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cytoplasm	IDA	15051713
cytoplasm	IBA
mitochondrion	IDA	18838503
membrane	IEA
intracellular membrane-bounded organelle	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle

mitochondrion

Displaying **all 4** entries
GO Term	Evidence Code	PMID
iron ion binding	IEA
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	IBA
heme binding	IBA
aromatase activity	IDA	15051713 18838503

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

monooxygenase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

aromatase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

aromatase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

heme binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Cytochrome p450

Functional Category

I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
heme binding
iron ion binding
metal ion binding
monooxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity

Displaying **all 4** entries
InterPro
Cytochrome P450 superfamily
Cytochrome P450, E-class, group I
Cytochrome P450, conserved site
Cytochrome P450

Ortholog

Displaying entries **31 - 40** of 63 in total

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Species	Gene ID	Orthologous MAtrix
Cricetulus griseus	100750508	CRIGR18470
Otolemur garnettii	100946358	OTOGA17342
Octodon degus	101578592	OCTDE21136
Octodon degus	101589870	OCTDE21178
Mustela putorius furo	101672586	MUSPF05355
Chinchilla lanigera	102007982	CHILA04612
Capra hircus	102169002	CAPHI25829
Capra hircus	102177333	CAPHI25828
Capra hircus	102179192	CAPHI32233
Myotis lucifugus	102420688	MYOLU11339