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MIRAGE

ATP-binding cassette, sub-family E member 1

Summary

Gene Symbol

Abce1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

24015

PubChem

24015

Alliance of Genome Resources

MGI:1195458

Annotation

Keyword

4Fe-4S
ATP-binding
Chaperone
Cytoplasm
Hydrolase
Mitochondrion
Phosphoprotein
Reference proteome
Repeat
Translation regulation
Ubl conjugation

Proteins

Displaying **all 3** entries
UniProt	Protein Name
P61222	RNase L inhibitor Ribonuclease 4 inhibitor
Q3TJM9
Q3UHY8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
translational initiation	IBA
translational termination	ISO
translational termination	IBA
translational termination	IEA
regulation of translation	IEA

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translational elongation [inference]

rescue of stalled ribosome

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translational elongation [inference]

rescue of stalled ribosome

cellular metabolic process [inference]

translational initiation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translational elongation [inference]

rescue of stalled ribosome

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

translational elongation [inference]

rescue of stalled ribosome

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translational elongation [inference]

rescue of stalled ribosome

cellular process [inference]

cellular metabolic process [inference]

translational initiation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translational elongation [inference]

rescue of stalled ribosome

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle disassembly [inference]

ribosome disassembly

rescue of stalled ribosome

cellular component disassembly [inference]

protein-containing complex disassembly [inference]

translational termination

organelle disassembly [inference]

ribosome disassembly

rescue of stalled ribosome

protein-containing complex organization [inference]

protein-containing complex disassembly [inference]

translational termination

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of ribonuclease activity [inference]

regulation of endoribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of ribonuclease activity [inference]

regulation of endoribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of amide metabolic process [inference]

regulation of translation

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of protein metabolic process [inference]

regulation of translation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation

negative regulation of macromolecule metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of nuclease activity [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of ribonuclease activity [inference]

regulation of endoribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of protein metabolic process [inference]

regulation of translation

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of ribonuclease activity [inference]

regulation of endoribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of ribonuclease activity [inference]

regulation of endoribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of protein metabolic process [inference]

regulation of translation

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of ribonuclease activity [inference]

regulation of endoribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of RNA metabolic process [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of hydrolase activity [inference]

regulation of nuclease activity [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

regulation of ribonuclease activity [inference]

regulation of endoribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

negative regulation of hydrolase activity [inference]

negative regulation of nuclease activity [inference]

negative regulation of ribonuclease activity [inference]

negative regulation of endoribonuclease activity

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
cytoplasm	ISS
cytoplasm	ISO
mitochondrion	ISS
mitochondrion	ISO
cytosol	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

ribosome [inference]

cytosolic ribosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular non-membrane-bounded organelle [inference]

ribosome [inference]

cytosolic ribosome

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
GTPase activity	ISS
GTPase activity	ISO
iron ion binding	IBA
ATP binding	IBA
ATP binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

iron ion binding

protein-containing complex binding [inference]

ribonucleoprotein complex binding [inference]

ribosome binding [inference]

ribosomal small subunit binding

metal cluster binding [inference]

iron-sulfur cluster binding [inference]

4 iron, 4 sulfur cluster binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

nuclease inhibitor activity [inference]

ribonuclease inhibitor activity [inference]

endoribonuclease inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

nuclease inhibitor activity [inference]

ribonuclease inhibitor activity [inference]

endoribonuclease inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ATP-binding cassette sub-family e member 1

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
iron ion binding
nucleotide binding
ribosomal small subunit binding
ribosomal subunit export from nucleus

Displaying **all 8** entries
InterPro
4Fe-4S ferredoxin-type, iron-sulphur binding domain
AAA+ ATPase domain
ABC transporter-like, ATP-binding domain
ABC transporter-like, conserved site
P-loop containing nucleoside triphosphate hydrolase
RLI, domain 1
RLI1
RNase L inhibitor RLI-like, possible metal-binding domain

Ortholog

Displaying entries **1 - 10** of 91 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	6059	Xenbase:XB-GENE-993988	HUMAN77572
Xenopus tropicalis	24015	Xenbase:XB-GENE-993988
Rattus norvegicus	361390		RATNO14433
Danio rerio	406324		DANRE25107
Pan troglodytes	461523		PANTR34576
Canis lupus familiaris	475454		CANLF04302
Bos taurus	514991		BOVIN09119
Macaca mulatta	701945		MACMU35959
Xenopus tropicalis	851665	Xenbase:XB-GENE-993988
Monodelphis domestica	100018979		MONDO28194

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Last updated: April 7, 2025