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fucosyltransferase 3 (Lewis blood group)

Summary

Gene Symbol

FUT3

Aliases

CD174
galactoside 3(4)-L-fucosyltransferase

Organism

Homo sapiens (human)

External Links

NCBI Gene

2525

GGDB ID

gg003

HGNC

4014

mRNA

NM_000149

map

19p13.3

Protein

NP_000140

OMIM

111100

KEGG Gene ID

hsa:2525

PubChem

2525

Alliance of Genome Resources

HGNC:4014

Annotation

Keyword

Blood group antigen
Glycoprotein
Glycosyltransferase
Golgi apparatus
Lipid metabolism
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A8K737
P21217	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase Alpha-3-fucosyltransferase FUT3 Blood group Lewis alpha-4-fucosyltransferase Fucosyltransferase 3 Fucosyltransferase III

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 11 in total

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GO Term	Evidence Code	PMID
macromolecule glycosylation	IDA	12668675 1977660
protein O-linked glycosylation	IDA	29593094
oligosaccharide metabolic process	IDA	1740457
protein N-linked glycosylation	IDA	29593094
cell-cell recognition	IC	12668675

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

ceramide metabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

glycosylation [inference]

fucosylation

macromolecule glycosylation

protein glycosylation [inference]

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

macromolecule glycosylation

protein glycosylation [inference]

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

cellular process [inference]

cell recognition [inference]

cell-cell recognition

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion

regulation of cellular process [inference]

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion

regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion

regulation of cell motility [inference]

regulation of cell migration

Displaying **all 4** entries
GO Term	Evidence Code	PMID
membrane	IDA	1977660
Golgi cisterna membrane	IEA
Golgi membrane	TAS
extracellular exosome	HDA	19199708

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

Golgi cisterna membrane

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	32296183 33961781
3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity	IDA IMP TAS	10211701 11058871 1740457 1977660 7721776
alpha-(1->3)-fucosyltransferase activity	IBA IDA TAS	1977660
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	IDA IMP	10211701 11058871 12668675 1740457 1977660 29593094 7721776
fucosyltransferase activity	IDA	12668675 7721776