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peripherin 2

Summary

Gene Symbol

Prph2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

25534

PubChem

25534

Alliance of Genome Resources

RGD:3549

Annotation

Keyword

Cell adhesion
Cell projection
Disulfide bond
Glycoprotein
Reference proteome
Transmembrane helix
Vision

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P17438	Retinal degeneration slow protein
A6JIL5	Retinal degeneration slow protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
retina development in camera-type eye	ISO
protein maturation	IBA
response to low light intensity stimulus	IEP	8320859
cell adhesion	IEA
protein heterooligomerization	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein maturation

primary metabolic process [inference]

protein metabolic process [inference]

protein maturation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein maturation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein maturation

cellular process [inference]

cell adhesion

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

photoreceptor cell outer segment organization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

developmental process [inference]

anatomical structure development [inference]

retina development in camera-type eye

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus [inference]

detection of visible light [inference]

detection of light stimulus involved in visual perception

detection of light stimulus involved in sensory perception [inference]

detection of light stimulus involved in visual perception

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

detection of light stimulus [inference]

detection of visible light [inference]

detection of light stimulus involved in visual perception

detection of light stimulus involved in sensory perception [inference]

detection of light stimulus involved in visual perception

response to light intensity [inference]

response to low light intensity stimulus

detection of abiotic stimulus [inference]

detection of light stimulus [inference]

detection of visible light [inference]

detection of light stimulus involved in visual perception

detection of light stimulus involved in sensory perception [inference]

detection of light stimulus involved in visual perception

detection of stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus [inference]

detection of visible light [inference]

detection of light stimulus involved in visual perception

detection of light stimulus involved in sensory perception [inference]

detection of light stimulus involved in visual perception

detection of abiotic stimulus [inference]

detection of light stimulus [inference]

detection of visible light [inference]

detection of light stimulus involved in visual perception

detection of light stimulus involved in sensory perception [inference]

detection of light stimulus involved in visual perception

detection of stimulus involved in sensory perception [inference]

detection of light stimulus involved in sensory perception [inference]

detection of light stimulus involved in visual perception

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA
photoreceptor outer segment	ISO
photoreceptor inner segment	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
protein homodimerization activity	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

peripherin-2

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
visual perception

Displaying **all 5** entries
InterPro
Peripherin, extracellular domain
Peripherin/rom-1, conserved site
Peripherin/rom-1
Tetraspanin, EC2 domain superfamily
Tetraspanin/Peripherin

Disease

Disease Ontology

Displaying entries **1 - 10** of 12 in total

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DO ID	Disease Name	Source
DOID:0050661	vitelliform macular dystrophy	Alliance of Genome Resources
DOID:0060863	patterned macular dystrophy	Alliance of Genome Resources
DOID:0060866	patterned macular dystrophy 1	Alliance of Genome Resources
DOID:0110383	retinitis pigmentosa 7	Alliance of Genome Resources
DOID:10584	retinitis pigmentosa	Alliance of Genome Resources
DOID:11105	fundus albipunctatus	Alliance of Genome Resources
DOID:14791	Leber congenital amaurosis	Alliance of Genome Resources
DOID:4448	macular degeneration	Alliance of Genome Resources
DOID:5679	retinal disease	Alliance of Genome Resources
DOID:8466	retinal degeneration	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **132** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	5961		HGNC:9942	HUMAN84815
Mus musculus	19133	10090_1:004f4b	MGI:102791	MOUSE22565
Drosophila melanogaster	34590		FB:FBgn0032376
Drosophila melanogaster	35617		FB:FBgn0033129
Drosophila melanogaster	37786		FB:FBgn0020372
Danio rerio	58085		ZFIN:ZDB-GENE-000616-8	DANRE03868
Bos taurus	280907			BOVIN18504
Canis lupus familiaris	403972			CANLF02752
Danio rerio	559209		ZFIN:ZDB-GENE-000616-9
Macaca mulatta	696630			MACMU34462

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements