glyceraldehyde-3-phosphate dehydrogenase

Summary
Gene Symbol
  • GAPDH
Organism
Homo sapiens (human)
External Links
NCBI Gene
2597
HGNC
4141
KEGG Gene ID
hsa:2597
PubChem
2597
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • ADP-ribosylation
  • Acetylation
  • Alternative splicing
  • Apoptosis
  • Cytoskeleton
  • Direct protein sequencing
  • Glycolysis
  • Glycoprotein
  • Innate immunity
  • Isopeptide bond
  • Membrane
  • Methylation
  • NAD
  • Nucleotide-binding
  • Nucleus
  • Oxidation
  • Oxidoreductase
  • Phosphoprotein
  • Reference proteome
  • S-nitrosylation
  • Transferase
  • Translation regulation
  • Ubl conjugation
Proteins
Displaying all 2 entries
UniProt Protein Name
P04406
  • Peptidyl-cysteine S-nitrosylase GAPDH
V9HVZ4
Gene Ontology (GO)
Displaying entries 16 - 17 of 17 in total
GO Term Evidence Code PMID
positive regulation of canonical NF-kappaB signal transduction
glycolytic process
GO Hierarchy
GO Hierarchy
Human Protein Atlas
ENSG00000111640

soft tissue soft tissue blood blood blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node kidney kidney adrenal gland adrenal gland breast breast duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland nasopharynx nasopharynx tongue tonsil tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder ductus deferens ductus deferens seminal vesicle seminal vesicle seminal vesicle seminal vesicle testis testis epididymis epididymis brain smooth muscle urinary bladder prostate bone marrow skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus cartilage sole of foot sole of foot soft tissue blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lactating breast lactating breast kidney kidney adrenal gland adrenal gland duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland salivary gland salivary gland salivary gland salivary gland salivary gland nasopharynx tongue tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder brain skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus smooth muscle urinary bladder vagina ovary ovary fallopian tube fallopian tube endometrium placenta cervix cervix bone marrow cartilage sole of foot sole of foot olfactory region cerebral cortex cerebellum medulla pons midbrain pituitary gland hypothalamus amygdala thalamus choroid plexus choroid plexus corpus callosum basal ganglia substantia nigra dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe caudate hippocampus retina retina

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

KEGG BRITE Database
Orthology
K00134
Name
glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
References
Disease
Disease Ontology
Displaying entries 1 - 10 of 269 in total
DO ID Disease Name Source
DOID:0040085 bacterial sepsis
DOID:0050083 Keshan disease
DOID:0050387 nonpapillary renal cell carcinoma
DOID:0050457 Sertoli cell-only syndrome
DOID:0050569 Seckel syndrome
DOID:0050589 inflammatory bowel disease
DOID:0050597 intestinal schistosomiasis
DOID:0050700 cardiomyopathy
DOID:0050709 early infantile epileptic encephalopathy
DOID:0050741 alcohol dependence

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024