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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
cytochrome P450 family 4 subfamily A member 22
Summary
- Gene Symbol
-
- CYP4A22
- Organism
- Homo sapiens (human)
External Links
- NCBI Gene
- 284541
- HGNC
- 20575
- KEGG Gene ID
- hsa:284541
- PubChem
- 284541
- Alliance of Genome Resources
Annotation
- Keyword
-
- Alternative splicing
- Heme
- Lipid metabolism
- Membrane
- Microsome
- Monooxygenase
- NADP
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q5TCH5 |
|
| A5PL05 |
|
| A5PKT5 |
|
| A0A087WZX9 |
|
| Q5TCH4 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| icosanoid biosynthetic process | ||
| omega-hydroxylase P450 pathway | ||
| arachidonic acid metabolic process | ||
| linoleic acid metabolic process | ||
| lauric acid metabolic process |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum membrane | ||
| intracellular membrane-bounded organelle | ||
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| arachidonic acid omega-hydroxylase activity | ||
| arachidonic acid monooxygenase activity | ||
| 16-hydroxypalmitate dehydrogenase activity | ||
| alkane 1-monooxygenase activity | ||
| medium-chain fatty acid omega-hydroxylase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- cytochrome
- Functional Category
-
- C: Energy production and conversion
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| Cytochrome P450 superfamily |
| Cytochrome P450, E-class, group I |
| Cytochrome P450, conserved site |
| Cytochrome P450 |
KEGG BRITE Database
Rhea
- Enzyme
- PMID
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110861 | autosomal recessive polycystic kidney disease | |
| DOID:10763 | hypertension |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 13117 | MOUSE40567 | |||
| 13118 | MGI:3611747 | MOUSE40564 | ||
| 13119 | MGI:1096550 | MOUSE40566 | ||
| 24306 | RGD:2479 | RATNO32261 | ||
| 50549 | RATNO34495 | |||
| 170544 | RGD:68945 | |||
| 230639 | MGI:3717143 | MOUSE40562 | ||
| 266674 | RGD:628846 | RATNO32326 | ||
| 277753 | MGI:88612 | MOUSE40563 | ||
| 298423 | RGD:631356 | RATNO32281 |
