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glutamate ionotropic receptor AMPA type subunit 2
Summary
- Gene Symbol
-
- GRIA2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Autism spectrum disorder
- Cell membrane
- Disease variant
- Disulfide bond
- Epilepsy
- Glycoprotein
- Intellectual disability
- Ligand-gated ion channel
- Palmitate
- Phosphoprotein
- Postsynaptic cell membrane
- RNA editing
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P42262 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| monoatomic cation transmembrane transport | ||
| regulation of postsynaptic membrane potential | ||
| ionotropic glutamate receptor signaling pathway | ||
| synaptic transmission, glutamatergic | ||
| modulation of chemical synaptic transmission |
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| postsynaptic density membrane | ||
| postsynaptic density | ||
| postsynapse | ||
| neuronal cell body |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| ligand-gated monoatomic cation channel activity | ||
| AMPA glutamate receptor activity | ||
| glutamate-gated receptor activity | ||
| transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ligand-gated monoatomic ion channel activity |
| monoatomic ion transport |
| InterPro |
|---|
| Periplasmic binding protein-like I |
| Receptor, ligand binding region |
Disease
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 14800 | MGI:95809 | MOUSE36764 | ||
| 29627 | RGD:61862 | RATNO23581 | ||
| 38742 | FB:FBgn0004619 | |||
| 44484 | FB:FBgn0264000 | |||
| 170450 | ZFIN:ZDB-GENE-020125-3 | |||
| 170451 | ZFIN:ZDB-GENE-020125-4 | DANRE07390 | ||
| 175999 | WB:WBGene00001613 | |||
| 176204 | WB:WBGene00001612 | |||
| 443272 | SHEEP07229 | |||
| 461570 | 9598_0:0013d9 | PANTR34703 |
