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Imaginal disc growth factor 4

Summary

Gene Symbol

Idgf4

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

31926

PubChem

31926

Alliance of Genome Resources

FB:FBgn0026415

Annotation

Keyword

Developmental protein
Disulfide bond
Glycoprotein
Glycosidase
Proteomics identification
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
X2JEB6
Q9W303	Imaginal disk growth factor protein 4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
wound healing	IMP	26838602
chitin catabolic process	IBA
chitin-based cuticle development	IMP	26838602
imaginal disc development	IDA	9847235
ecdysis, chitin-based cuticle	IMP	26838602

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

chitin metabolic process [inference]

chitin catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

amino sugar catabolic process [inference]

glucosamine-containing compound catabolic process [inference]

chitin catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

chitin metabolic process [inference]

chitin catabolic process

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

chitin metabolic process [inference]

chitin catabolic process

amino sugar metabolic process [inference]

amino sugar catabolic process [inference]

glucosamine-containing compound catabolic process [inference]

chitin catabolic process

glucosamine-containing compound metabolic process [inference]

chitin metabolic process [inference]

chitin catabolic process

glucosamine-containing compound catabolic process [inference]

chitin catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

amino sugar catabolic process [inference]

glucosamine-containing compound catabolic process [inference]

chitin catabolic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

chitin metabolic process [inference]

chitin catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

amino sugar catabolic process [inference]

glucosamine-containing compound catabolic process [inference]

chitin catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

multicellular organismal process [inference]

molting cycle process [inference]

ecdysis, chitin-based cuticle

developmental process [inference]

anatomical structure development [inference]

cuticle development [inference]

chitin-based cuticle development

animal organ development [inference]

imaginal disc development

response to stimulus [inference]

response to stress [inference]

response to wounding [inference]

wound healing

Displaying 1 entry
GO Term	Evidence Code	PMID
extracellular region	HDA IBA NAS	15466469 9847235

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

Displaying **all 2** entries
GO Term	Evidence Code	PMID
chitin binding	IEA
imaginal disc growth factor receptor binding	IDA	9847235

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

growth factor receptor binding [inference]

imaginal disc growth factor receptor binding

carbohydrate derivative binding [inference]

chitin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Chitinase A

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 5** entries
Gene Ontology
chitin binding
chitin catabolic process
chitinase activity
hydrolase activity, acting on glycosyl bonds
hydrolase activity

Displaying **all 5** entries
InterPro
Chitinase II
Chitinase insertion domain superfamily
Glycoside hydrolase family 18, catalytic domain
Glycoside hydrolase superfamily
Glycosyl hydrolases family 18 (GH18) active site

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
cytoplasm	FB:FBrf0219073
extracellular region	PMID:15466469
membrane	FB:FBrf0231198

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:418	systemic scleroderma	Alliance of Genome Resources
DOID:5419	schizophrenia	Alliance of Genome Resources
DOID:5844	myocardial infarction	Alliance of Genome Resources
DOID:6000	congestive heart failure	Alliance of Genome Resources
DOID:7148	rheumatoid arthritis	Alliance of Genome Resources
DOID:9119	acute myeloid leukemia	Alliance of Genome Resources
DOID:9352	type 2 diabetes mellitus	Alliance of Genome Resources
DOID:9470	bacterial meningitis	Alliance of Genome Resources
DOID:9538	multiple myeloma	Alliance of Genome Resources
DOID:9744	type 1 diabetes mellitus	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 51 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Danio rerio	406323		ZFIN:ZDB-GENE-040426-1994
Danio rerio	406338		ZFIN:ZDB-GENE-040426-2014
Danio rerio	406819		ZFIN:ZDB-GENE-040426-2891
Xenopus tropicalis	448265		Xenbase:XB-GENE-5801457
Drosophila pseudoobscura	4814222	7237_0:000843
Drosophila ananassae	6501923	7217_1:003818
Drosophila yakuba	6525961	7245_0:0025b0
Drosophila erecta	6551708	7220_1:003229
Drosophila grimshawi	6564556	7222_1:002c2d
Drosophila mojavensis	6584918	7230_1:000752

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Annotation

OrthoDB (Group)

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Acknowledgements