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hydroxysteroid 11-beta dehydrogenase 1

Summary

Gene Symbol

HSD11B1

Aliases

SDR26C1
short chain dehydrogenase/reductase family 26C, member 1

Organism

Homo sapiens (human)

External Links

NCBI Gene

3290

HGNC

5208

KEGG Gene ID

hsa:3290

PubChem

3290

Alliance of Genome Resources

HGNC:5208

Annotation

Keyword

3D-structure
Disease variant
Endoplasmic reticulum
Glycoprotein
NADP
Oxidoreductase
Reference proteome
Signal-anchor
Steroid metabolism
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P28845	7-oxosteroid reductase Corticosteroid 11-beta-dehydrogenase isozyme 1 Short chain dehydrogenase/reductase family 26C member 1
X5D2L1	7-oxosteroid reductase Corticosteroid 11-beta-dehydrogenase isozyme 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
steroid catabolic process	IBA
lung development	IEA

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

organic substance catabolic process [inference]

lipid catabolic process [inference]

steroid catabolic process

organic cyclic compound catabolic process [inference]

steroid catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid catabolic process

lipid catabolic process [inference]

steroid catabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid catabolic process

lipid catabolic process [inference]

steroid catabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid catabolic process

organic cyclic compound catabolic process [inference]

steroid catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

steroid catabolic process

organic cyclic compound catabolic process [inference]

steroid catabolic process

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

lung development

Displaying **all 3** entries
GO Term	Evidence Code	PMID
intracellular membrane-bounded organelle	IBA
endoplasmic reticulum membrane	IBA IDA TAS	10497248
membrane	HDA	19946888

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

Displaying entry **6 - 6** of 6 in total

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GO Term	Evidence Code	PMID
7-beta-hydroxysteroid dehydrogenase (NADP+) activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

steroid dehydrogenase activity [inference]

steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [inference]

11-beta-hydroxysteroid dehydrogenase (NADP+) activity

7-beta-hydroxysteroid dehydrogenase (NADP+) activity

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity [inference]

11-beta-hydroxysteroid dehydrogenase (NADP+) activity

7-beta-hydroxysteroid dehydrogenase (NADP+) activity

cortisol dehydrogenase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

lipid binding [inference]

steroid binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

organic cyclic compound binding [inference]

steroid binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000117594

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

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Annotation