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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
heparan sulfate proteoglycan 2
Summary
- Gene Symbol
-
- HSPG2
- Aliases
-
- PRCAN
- endorepellin
- perlecan
- perlecan proteoglycan
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Angiogenesis
- Basement membrane
- Calcium
- Direct protein sequencing
- Disease variant
- Disulfide bond
- EGF-like domain
- Heparan sulfate
- Immunoglobulin domain
- Laminin EGF-like domain
- Metal-binding
- Reference proteome
- Repeat
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P98160 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to hypoxia | ||
| circulatory system development |
|
|
| lipid metabolic process |
|
|
| embryo implantation | ||
| inflammatory response |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| Golgi lumen |
|
|
| basement membrane |
|
|
| plasma membrane |
|
|
| focal adhesion |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| low-density lipoprotein particle receptor binding |
|
|
| amyloid-beta binding | ||
| extracellular matrix structural constituent conferring compression resistance | ||
| calcium ion binding | ||
| protein binding |
GO Hierarchy
KEGG BRITE Database
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:4001 | ovarian carcinoma | |
| DOID:4015 | sarcomatoid carcinoma | |
| DOID:417 | autoimmune disease | |
| DOID:418 | systemic scleroderma | |
| DOID:419 | scleroderma | |
| DOID:4195 | hyperglycemia | |
| DOID:4254 | osteosclerosis | |
| DOID:4411 | hepatitis E | |
| DOID:4448 | macular degeneration | |
| DOID:4480 | achondroplasia |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000023 | Inguinal hernia |
| HP:0000028 | Cryptorchidism |
| HP:0000047 | Hypospadias |
| HP:0000055 | Abnormal female external genitalia morphology |
| HP:0000069 | Abnormality of the ureter |
| HP:0000077 | Abnormality of the kidney |
| HP:0000079 | Abnormality of the urinary system |
| HP:0000107 | Renal cyst |
| HP:0000119 | Abnormality of the genitourinary system |
| Disease ID | Disease Name |
|---|---|
| ORPHA:1606 |
|
| ORPHA:800 |
|
| ORPHA:1865 |
|
| OMIM:255800 |
|
| OMIM:224410 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100340334 | RABIT04131 | ||
| 105997956 | DIPOR06164 | ||
| 100689041 | CRIGR11652 | ||
| 15530 | MGI:96257 | MOUSE41252 | |
| 313641 | RGD:621770 | RATNO33334 | |
| 100718406 | CAVPO12019 | ||
| 101568186 | OCTDE15733 | ||
| 100617792 | MONDO25064 | ||
| 114027391 | VOMUR26221 | ||
| 113879542 | BOBOX38086 |
