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F27C1.11 Doublecortin domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 3565116, updated on 9-Dec-2024

Summary

Official Symbol
F27C1.11
Official Full Name
Doublecortin domain-containing protein
Primary source
WormBase:WBGene00017858
Locus tag
CELE_F27C1.11
See related
AllianceGenome:WB:WBGene00017858
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in intracellular signal transduction. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy; autosomal recessive nonsyndromic deafness 77; and orofacial cleft. Orthologous to human LOXHD1 (lipoxygenase homology PLAT domains 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See F27C1.11 in Genome Data Viewer
Location:
chromosome: I
Exon count:
28
Sequence:
Chromosome: I; NC_003279.8 (5433905..5443026, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Cuticle collagen dpy-5 Neighboring gene Ovule protein Neighboring gene Doublecortin domain-containing protein Neighboring gene ncRNA

General gene information

Gene Ontology Provided by WormBase

General protein information

Preferred Names
Doublecortin domain-containing protein
NP_001362169.1
  • Confirmed by transcript evidence
NP_001362170.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    5433905..5443026 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001374895.3NP_001362170.1  Doublecortin domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5K1IAB7
    Conserved Domains (4) summary
    cd00113
    Location:713823
    PLAT; PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and ...
    cd01617
    Location:2694
    DCX; Dublecortin-like domain structurally similar to a beta-grasp ubiquitin-like fold
    pfam11179
    Location:89407
    DUF2967; Protein of unknown function (DUF2967)
    cl00011
    Location:564684
    PLAT; PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and ...
  2. NM_001374894.3NP_001362169.1  Doublecortin domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5K1IBA0
    Conserved Domains (4) summary
    cd00113
    Location:713823
    PLAT; PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and ...
    PTZ00112
    Location:95410
    PTZ00112; origin recognition complex 1 protein; Provisional
    cd01617
    Location:2694
    DCX; Dublecortin-like domain structurally similar to a beta-grasp ubiquitin-like fold
    cl00011
    Location:564684
    PLAT; PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and ...
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