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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
beta-secretase 2 S homeolog
Summary
- Gene Symbol
-
- bace2.S
- Organism
- Xenopus laevis (African clawed frog)
Annotation
- Keyword
-
- Aspartyl protease
- Disulfide bond
- Glycoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A974DH44 |
|
| Q6PB20 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| membrane protein ectodomain proteolysis | ||
| amyloid-beta metabolic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| plasma membrane | ||
| endosome | ||
| trans-Golgi network |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| aspartic-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- aspartic
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| aspartic-type endopeptidase activity |
| proteolysis |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10652 | Alzheimer's disease | |
| DOID:9255 | frontotemporal dementia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 25825 | 9606_0:001a2a | HGNC:934 | ||
| 418526 | 9031_0:00070f | |||
| 478418 | 9615_0:00495e | |||
| 534774 | 9913_0:0001df | |||
| 715330 | 9544_0:000e5f | |||
| 100016587 | 13616_0:00344b | |||
| 100058700 | 9796_0:00491c | |||
| 100080196 | 9258_0:0034aa | |||
| 100216145 | 8364_0:001138 | Xenbase:XB-GENE-1014090 | ||
| 100224177 | 59729_0:000047 |
