U.S. flag

An official website of the United States government

itga3a integrin, alpha 3a [ Danio rerio (zebrafish) ]

Gene ID: 407685, updated on 9-Dec-2024

Summary

Official Symbol
itga3aprovided by ZNC
Official Full Name
integrin, alpha 3aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-090805-3
See related
Ensembl:ENSDARG00000037917 AllianceGenome:ZFIN:ZDB-GENE-090805-3
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable integrin binding activity. Predicted to be involved in several processes, including cell adhesion mediated by integrin; cell-matrix adhesion; and integrin-mediated signaling pathway. Predicted to act upstream of or within cell adhesion. Predicted to be located in membrane. Predicted to be part of integrin complex. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa. Orthologous to human ITGA3 (integrin subunit alpha 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See itga3a in Genome Data Viewer
Location:
chromosome: 3
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (34846190..34919628)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (34716670..34787736)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene proteasome 26S subunit, non-ATPase 11a Neighboring gene cyclin dependent kinase 5, regulatory subunit 1a (p35) Neighboring gene carbonic anhydrase Xb Neighboring gene fatty acid-binding protein, heart-like Neighboring gene SWI/SNF related BAF chromatin remodeling complex subunit E1

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
part_of integrin complex  
located_in membrane  

General protein information

Preferred Names
Integrin alpha-3; integrin alpha-3
Names
integrin alpha 3

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    34846190..34919628
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_691769.10XP_696861.6  integrin alpha-3 isoform X2

    See identical proteins and their annotated locations for XP_696861.6

    UniProtKB/TrEMBL
    A0A8M9QA60, F1R108
    Related
    ENSDARP00000055262.5, ENSDART00000055263.6
    Conserved Domains (2) summary
    smart00191
    Location:304360
    Int_alpha; Integrin alpha (beta-propellor repeats)
    pfam08441
    Location:461919
    Integrin_alpha2; Integrin alpha
  2. XM_017354802.3XP_017210291.1  integrin alpha-3 isoform X1

    UniProtKB/TrEMBL
    A0A8M6YWS7
  3. XM_021474550.2XP_021330225.1  integrin alpha-3 isoform X2

    UniProtKB/TrEMBL
    A0A8M9QA60, F1R108
    Conserved Domains (2) summary
    smart00191
    Location:304360
    Int_alpha; Integrin alpha (beta-propellor repeats)
    pfam08441
    Location:461919
    Integrin_alpha2; Integrin alpha
  4. XM_005164095.5XP_005164152.1  integrin alpha-3 isoform X2

    See identical proteins and their annotated locations for XP_005164152.1

    UniProtKB/TrEMBL
    A0A8M9QA60, F1R108
    Conserved Domains (2) summary
    smart00191
    Location:304360
    Int_alpha; Integrin alpha (beta-propellor repeats)
    pfam08441
    Location:461919
    Integrin_alpha2; Integrin alpha
External link. Please review our privacy policy.