GlyCosmos Portal

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
DNA N-glycosylase activity	TAS
MutLbeta complex binding	IDA	11801590
adenine/guanine mispair binding	IBA
4 iron, 4 sulfur cluster binding	IEA
MutSalpha complex binding	IDA	11801590

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

DNA N-glycosylase activity

mismatch base pair DNA N-glycosylase activity [inference]

purine-specific mismatch base pair DNA N-glycosylase activity

oxidized base lesion DNA N-glycosylase activity [inference]

oxidized purine nucleobase lesion DNA N-glycosylase activity [inference]

8-oxo-7,8-dihydroguanine DNA N-glycosylase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

DNA N-glycosylase activity

mismatch base pair DNA N-glycosylase activity [inference]

purine-specific mismatch base pair DNA N-glycosylase activity

oxidized base lesion DNA N-glycosylase activity [inference]

oxidized purine nucleobase lesion DNA N-glycosylase activity [inference]

8-oxo-7,8-dihydroguanine DNA N-glycosylase activity

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

mismatch repair complex binding [inference]

metal cluster binding [inference]

iron-sulfur cluster binding [inference]

4 iron, 4 sulfur cluster binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding [inference]

damaged DNA binding [inference]

oxidized DNA binding [inference]

oxidized purine DNA binding

double-stranded DNA binding [inference]

mismatched DNA binding [inference]

adenine/guanine mispair binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying entries **31 - 40** of **150** in total

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DO ID	Disease Name	Source
DOID:12858	Huntington's disease	DisGeNET
DOID:1289	neurodegenerative disease	DisGeNET
DOID:1324	lung cancer	DisGeNET DisGeNET
DOID:1325	bronchus cancer	DisGeNET
DOID:1380	endometrial cancer	DisGeNET DisGeNET DisGeNET
DOID:14175	von Hippel-Lindau disease	DisGeNET
DOID:1470	major depressive disorder	DisGeNET DisGeNET
DOID:1520	colon carcinoma	DisGeNET
DOID:1595	melancholic depression	DisGeNET
DOID:1596	depressive disorder	DisGeNET DisGeNET DisGeNET

The Human Phenotype Ontology

Displaying entries **1 - 10** of 61 in total

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HPO ID	HPO Term
HP:0000007	Autosomal recessive inheritance
HP:0000505	Visual impairment
HP:0000708	Atypical behavior
HP:0000716	Depression
HP:0000737	Irritability
HP:0000738	Hallucinations
HP:0000739	Anxiety
HP:0001123	Visual field defect
HP:0001250	Seizure
HP:0001252	Hypotonia

Displaying **all 4** entries
Disease ID	Disease Name
OMIM:613659	gastric cancer
ORPHA:440437	familial colorectal cancer type X
ORPHA:247798	familial adenomatous polyposis 2
OMIM:608456	familial adenomatous polyposis 2

PubChem Disease

GHR Health Conditions

Familial adenomatous polyposis

MedGen Diseases

OMIM Phenotypes

KEGG Diseases

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

Ortholog

Displaying entries **41 - 50** of 63 in total

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Species	Gene ID	Orthologous MAtrix
Bos indicus x Bos taurus	113889965	BOBOX07546
Microcebus murinus	105877457	MICMU04257
Otolemur garnettii	100965263	OTOGA02361
Takifugu rubripes	101076441	TAKRU26759
Aotus nancymaae	105705098	AOTNA11581
Phascolarctos cinereus	110209274	PHACI16211
Saimiri boliviensis boliviensis	101028546	SAIBB27576
Seriola dumerili	111232084	SERDU20514
Ictidomys tridecemlineatus	101968388	ICTTR09141
Poecilia formosa	103142549	POEFO09845