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zinc activated ion channel

Summary

Gene Symbol

ZACN

Organism

Canis lupus familiaris (dog)

External Links

NCBI Gene: 483326
PubChem: 483326

Annotation

Keyword

Cell membrane
Disulfide bond
Glycoprotein
Ligand-gated ion channel
Receptor
Reference proteome
Signal
Transmembrane helix
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
Q866Y9	Zinc-activated channel

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
ion transmembrane transport	IEA	30032202
nervous system process	IEA	30032202
monoatomic ion transmembrane transport	IEA	30032202
regulation of membrane potential	IEA	30032202
signal transduction	IEA	30032202

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

signal transduction

transmembrane transport [inference]

monoatomic ion transmembrane transport

multicellular organismal process [inference]

system process [inference]

nervous system process

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

regulation of cellular process [inference]

signal transduction

regulation of biological quality [inference]

regulation of membrane potential

Displaying **all 5** entries
GO Term	Evidence Code	PMID
membrane	IEA	22301074 30032202
plasma membrane
neuron projection	IEA	30032202
transmembrane transporter complex
synapse	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex

transporter complex [inference]

transmembrane transporter complex

cellular anatomical entity [inference]

membrane

plasma membrane

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

Displaying **all 4** entries
GO Term	Evidence Code	PMID
ligand-gated monoatomic cation channel activity
neurotransmitter receptor activity	IEA	30032202
extracellular ligand-gated monoatomic ion channel activity	IEA	22301074
transmembrane signaling receptor activity	IEA	30032202

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity

ligand-gated monoatomic ion channel activity [inference]

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

ligand-gated monoatomic cation channel activity

ligand-gated monoatomic ion channel activity [inference]

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

molecular transducer activity [inference]

signaling receptor activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Neuronal acetylcholine receptor

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
extracellular ligand-gated monoatomic ion channel activity
monoatomic ion channel activity
monoatomic ion transport

Displaying **all 3** entries
InterPro
Neurotransmitter-gated ion-channel ligand-binding domain superfamily
Neurotransmitter-gated ion-channel ligand-binding domain
Neurotransmitter-gated ion-channel

Ortholog

Displaying entries **1 - 10** of 74 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Homo sapiens	353174		HUMAN36404
Pan troglodytes	468333		PANTR15480
Macaca mulatta	705940		MACMU14638
Bos taurus	789168		BOVIN13949
Monodelphis domestica	100026931		MONDO10771
Oryctolagus cuniculus	100358831		RABIT16968
Callithrix jacchus	100393050		CALJA36223
Pongo abelii	100460952		PONAB12188
Ailuropoda melanoleuca	100481347	9646_0:0035ba	AILME12168
Nomascus leucogenys	100580902		NOMLE09270