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fst follistatin [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 493419, updated on 9-Dec-2024

Summary

Official Symbol
fstprovided by Xenbase
Official Full Name
follistatinprovided by Xenbase
Primary source
Xenbase:XB-GENE-486296
See related
Ensembl:ENSXETG00000023385 AllianceGenome:Xenbase:XB-GENE-486296
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
FS; xfs; foll
Summary
Is expressed in mesoderm. Human ortholog(s) of this gene implicated in polycystic ovary syndrome. Orthologous to human FST (follistatin). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See fst in Genome Data Viewer
Location:
chromosome: 1
Exon count:
5
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 1 NC_030677.2 (192424484..192431493, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 1 NC_030677.1 (179537008..179543877, complement)

Chromosome 1 - NC_030677.2Genomic Context describing neighboring genes Neighboring gene ARF like GTPase 15 Neighboring gene protein kinase C theta type-like Neighboring gene NADH:ubiquinone oxidoreductase subunit S4 Neighboring gene molybdopterin synthase catalytic subunit Neighboring gene molybdenum cofactor synthesis 2 Neighboring gene integrin subunit alpha 2

Genomic regions, transcripts, and products

General gene information

Clone Names

  • MGC79635

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables activin binding  
Process Evidence Code Pubs
involved_in cell differentiation  
involved_in negative regulation of activin receptor signaling pathway  
involved_in regulation of BMP signaling pathway  
Component Evidence Code Pubs
is_active_in extracellular region  
is_active_in extracellular space  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008056.1NP_001008057.1  follistatin

    See identical proteins and their annotated locations for NP_001008057.1

    Status: PROVISIONAL

    Source sequence(s)
    BC080943
    UniProtKB/TrEMBL
    A0A6I8QBS6, Q66JE7
    Related
    ENSXETP00000057786.2, ENSXETT00000057786.4
    Conserved Domains (1) summary
    smart00280
    Location:192239
    KAZAL; Kazal type serine protease inhibitors

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030677.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    192424484..192431493 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012960359.3XP_012815813.1  follistatin isoform X1

    UniProtKB/TrEMBL
    A0A8J0SH85, F6VV27
    Related
    ENSXETP00000050531.4, ENSXETT00000050531.4
    Conserved Domains (2) summary
    smart00274
    Location:167190
    FOLN; Follistatin-N-terminal domain-like
    smart00280
    Location:192239
    KAZAL; Kazal type serine protease inhibitors
  2. XM_031898689.1XP_031754549.1  follistatin isoform X2

    UniProtKB/TrEMBL
    A0A6I8QBS6, A0A8J1J9K9
    Conserved Domains (1) summary
    smart00280
    Location:192239
    KAZAL; Kazal type serine protease inhibitors
  3. XM_012960363.3XP_012815817.1  follistatin isoform X3

    UniProtKB/TrEMBL
    A0A6I8QBS6, A0A8J0SK32
    Related
    ENSXETP00000064386.2, ENSXETT00000076202.2
    Conserved Domains (1) summary
    smart00280
    Location:192239
    KAZAL; Kazal type serine protease inhibitors
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