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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
acyl-CoA oxidase 1
Summary
- Gene Symbol
-
- ACOX1
- Aliases
-
- PALMCOX
- palmitoyl-CoA oxidase
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acetylation
- Alternative splicing
- Deafness
- Disease variant
- FAD
- Fatty acid metabolism
- Neuropathy
- Oxidoreductase
- Peroxisome
- Phosphoprotein
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| Q15067 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| hydrogen peroxide biosynthetic process | ||
| fatty acid beta-oxidation using acyl-CoA oxidase | ||
| spermatogenesis | ||
| fatty acid catabolic process | ||
| lipid metabolic process |
GO Hierarchy
biological process
metabolic process [inference]
catabolic process [inference]
cellular metabolic process [inference]
primary metabolic process [inference]
small molecule metabolic process [inference]
organic substance metabolic process [inference]
cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytosol |
|
|
| membrane | ||
| peroxisome | ||
| peroxisomal membrane | ||
| peroxisomal matrix |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| flavin adenine dinucleotide binding | ||
| protein homodimerization activity | ||
| fatty acid binding | ||
| acyl-CoA oxidase activity | ||
| PDZ domain binding |
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:8675 | obsolete ymphosarcoma | |
| DOID:906 | peroxisomal disease | |
| DOID:92 | speech disorder | |
| DOID:9256 | colorectal cancer | |
| DOID:9273 | citrullinemia | |
| DOID:9306 | mechanical strabismus | |
| DOID:9452 | steatotic liver disease | |
| DOID:9649 | congenital nystagmus | |
| DOID:9650 | pathologic nystagmus | |
| DOID:9837 | hypertropia |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001508 | Failure to thrive |
| HP:0001522 | Death in infancy |
| HP:0001939 | Abnormality of metabolism/homeostasis |
| HP:0002007 | Frontal bossing |
| HP:0002015 | Dysphagia |
| HP:0002093 | Respiratory insufficiency |
| HP:0002167 | Abnormality of speech or vocalization |
| HP:0002240 | Hepatomegaly |
| HP:0002312 | Clumsiness |
| HP:0002353 | EEG abnormality |
| Disease ID | Disease Name |
|---|---|
| ORPHA:2971 |
|
| OMIM:264470 |
|
| OMIM:618960 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP002411
- Gene Name
- acyl-CoA oxidase 1, palmitoyl
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100172283 | PONAB12116 | ||
| 483322 | CANLF18437 | ||
| 112920813 | VULVU13430 | ||
| 123802961 | URSAM28006 | ||
| 100471606 | AILME12161 | ||
| 101670505 | MUSPF14973 | ||
| 101082279 | FELCA32798 | ||
| 122207307 | PANLE04240 | ||
| 101338715 | TURTR15630 | ||
| 118886954 | BALMU10052 |
