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ethanolamine kinase 1

Summary

Gene Symbol

ETNK1

Aliases

EKI
EKI1

Organism

Homo sapiens (human)

External Links

NCBI Gene

55500

HGNC

24649

KEGG Gene ID

hsa:55500

PubChem

55500

Alliance of Genome Resources

HGNC:24649

Annotation

Keyword

ATP-binding
Alternative splicing
Cytoplasm
Kinase
Phospholipid biosynthesis
Proteomics identification
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9HBU6
Q86U68

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
phosphatidylethanolamine biosynthetic process	IBA IDA IEA	11044454
phosphorylation	IEA

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

phosphorylation

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

phosphorylation

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine biosynthetic process

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylethanolamine biosynthetic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane	HDA	19946888
cytosol	TAS
cytoplasm	IBA IDA	11044454

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	25416956 32296183
ATP binding	IEA
ethanolamine kinase activity	IBA IDA	11044454

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

ethanolamine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

ethanolamine kinase activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Ethanolamine kinase

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
ethanolamine kinase activity
phosphatidylethanolamine biosynthetic process

Displaying 1 entry
InterPro
Protein kinase-like domain superfamily

KEGG BRITE Database

Orthology

K00894

Name

ethanolamine kinase [EC:2.7.1.82]

References

15161093

Rhea

ATP + ethanolamine

H⁺ + ADP + phosphoethanolamine

Enzyme

2.7.1.82

PMID

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:10273	heart conduction disease	Alliance of Genome Resources
DOID:10907	microcephaly	Alliance of Genome Resources
DOID:1826	epilepsy	Alliance of Genome Resources

PubChem Disease

KEGG Diseases

Atypical chronic myeloid leukemia

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP002722
Gene Name: ethanolamine kinase 1

Ortholog

Displaying entries **21 - 30** of 69 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Jaculus jaculus	101604492			JACJA15889
Mustela putorius furo	101671509			MUSPF03353
Ficedula albicollis	101805965			FICAL11262
Melopsittacus undulatus	101880371			MELUD11339
Chinchilla lanigera	102024781			CHILA04431
Haplochromis burtoni	102301483			HAPBU03069
Latimeria chalumnae	102350527			LATCH16188
Pelodiscus sinensis	102456037			PELSI13145
Neolamprologus brichardi	102787194			NEOBR00784
Poecilia formosa	103155771			POEFO02012

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Last updated: December 9, 2024