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zinc finger DHHC-type palmitoyltransferase 7

Summary

Gene Symbol

ZDHHC7

Organism

Homo sapiens (human)

External Links

NCBI Gene

55625

PubChem

55625

Alliance of Genome Resources

HGNC:18459

Annotation

Keyword

Acyltransferase
Alternative splicing
Golgi apparatus
Palmitate
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9NXF8	Acyltransferase ZDHHC7 Zinc finger DHHC domain-containing protein 7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 14 in total

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GO Term	Evidence Code	PMID
glucose import in response to insulin stimulus	ISS
regulation of Fas signaling pathway	IMP	25301068
polarized epithelial cell differentiation	IMP	27380321
protein palmitoylation	IDA IMP	19001095 23034182
protein localization to plasma membrane	IBA IDA IMP	22031296

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein lipidation [inference]

protein palmitoylation

peptidyl-L-cysteine S-palmitoylation

peptidyl-amino acid modification [inference]

peptidyl-cysteine modification [inference]

peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine [inference]

peptidyl-L-cysteine S-palmitoylation

protein acylation [inference]

protein palmitoylation

peptidyl-L-cysteine S-palmitoylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein lipidation [inference]

protein palmitoylation

peptidyl-L-cysteine S-palmitoylation

peptidyl-amino acid modification [inference]

peptidyl-cysteine modification [inference]

peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine [inference]

peptidyl-L-cysteine S-palmitoylation

protein acylation [inference]

protein palmitoylation

peptidyl-L-cysteine S-palmitoylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein lipidation [inference]

protein palmitoylation

peptidyl-L-cysteine S-palmitoylation

peptidyl-amino acid modification [inference]

peptidyl-cysteine modification [inference]

peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine [inference]

peptidyl-L-cysteine S-palmitoylation

protein acylation [inference]

protein palmitoylation

peptidyl-L-cysteine S-palmitoylation

macromolecule modification [inference]

protein modification process [inference]

protein lipidation [inference]

protein palmitoylation

peptidyl-L-cysteine S-palmitoylation

peptidyl-amino acid modification [inference]

peptidyl-cysteine modification [inference]

peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine [inference]

peptidyl-L-cysteine S-palmitoylation

protein acylation [inference]

protein palmitoylation

peptidyl-L-cysteine S-palmitoylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein lipidation [inference]

protein palmitoylation

peptidyl-L-cysteine S-palmitoylation

peptidyl-amino acid modification [inference]

peptidyl-cysteine modification [inference]

peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine [inference]

peptidyl-L-cysteine S-palmitoylation

protein acylation [inference]

protein palmitoylation

peptidyl-L-cysteine S-palmitoylation

cellular process [inference]

signal transduction [inference]

hormone-mediated signaling pathway [inference]

steroid hormone mediated signaling pathway

intracellular steroid hormone receptor signaling pathway [inference]

intracellular receptor signaling pathway [inference]

intracellular steroid hormone receptor signaling pathway [inference]

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

polarized epithelial cell differentiation

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

establishment of protein localization to membrane [inference]

protein targeting to membrane

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to membrane

establishment of protein localization to membrane [inference]

protein targeting to membrane

protein localization to membrane [inference]

protein localization to plasma membrane

establishment of protein localization to membrane [inference]

protein targeting to membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

glucose transmembrane transport [inference]

glucose import [inference]

glucose import in response to insulin stimulus

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation [inference]

polarized epithelial cell differentiation

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to membrane

establishment of protein localization to membrane [inference]

protein targeting to membrane

protein localization to membrane [inference]

protein localization to plasma membrane

establishment of protein localization to membrane [inference]

protein targeting to membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

establishment of localization [inference]

transport [inference]

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

glucose transmembrane transport [inference]

glucose import [inference]

glucose import in response to insulin stimulus

organic substance transport [inference]

carbohydrate transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

glucose transmembrane transport [inference]

glucose import [inference]

glucose import in response to insulin stimulus

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to membrane

establishment of protein localization to membrane [inference]

protein targeting to membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

establishment of protein localization to membrane [inference]

protein targeting to membrane

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to membrane

establishment of protein localization to membrane [inference]

protein targeting to membrane

protein localization to membrane [inference]

protein localization to plasma membrane

establishment of protein localization to membrane [inference]

protein targeting to membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process

regulation of catabolic process [inference]

negative regulation of catabolic process

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of localization [inference]

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to cell-cell junction

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of cellular process [inference]

signal transduction [inference]

hormone-mediated signaling pathway [inference]

steroid hormone mediated signaling pathway

intracellular steroid hormone receptor signaling pathway [inference]

intracellular receptor signaling pathway [inference]

intracellular steroid hormone receptor signaling pathway [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to cell-cell junction

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
Golgi apparatus	IBA IDA	16647879 22031296
nucleoplasm	IDA
Golgi membrane	TAS
endoplasmic reticulum	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

nucleoplasm

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	32296183
protein-cysteine S-stearoyltransferase activity	IEA
palmitoyltransferase activity	IDA	23034182 28057756
protein-cysteine S-palmitoyltransferase activity	IBA IDA IMP TAS	22031296 25301068 27380321 28196865
protein-cysteine S-myristoyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

palmitoyltransferase activity

protein-cysteine S-palmitoyltransferase activity

S-acyltransferase activity [inference]

protein-cysteine S-acyltransferase activity [inference]

myristoyltransferase activity [inference]

protein-cysteine S-myristoyltransferase activity

catalytic activity, acting on a protein [inference]

protein-cysteine S-acyltransferase activity [inference]

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Palmitoyltransferase

Functional Category

I: Lipid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
palmitoyltransferase activity
protein-cysteine S-palmitoyltransferase activity
transferase activity

Displaying 1 entry
InterPro
Palmitoyltransferase, DHHC domain

Ortholog

Displaying entries **1 - 10** of 98 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	36757		FB:FBgn0034057
Mus musculus	102193		MGI:2142662	MOUSE58778
Rattus norvegicus	170906		RGD:620205	RATNO14870
Caenorhabditis elegans	172257		WB:WBGene00018009
Danio rerio	436875		ZFIN:ZDB-GENE-040718-346	DANRE14662
Pan troglodytes	454390	9598_0:00424f		PANTR12996
Canis lupus familiaris	489676			CANLF15891
Macaca mulatta	718634			MACMU26649
Equus caballus	100070274			HORSE30015
Ornithorhynchus anatinus	100075834			ORNAN02384