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ackr3b atypical chemokine receptor 3b [ Danio rerio (zebrafish) ]

Gene ID: 561050, updated on 9-Dec-2024

Summary

Official Symbol
ackr3bprovided by ZNC
Official Full Name
atypical chemokine receptor 3bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-031116-61
See related
Ensembl:ENSDARG00000058179 AllianceGenome:ZFIN:ZDB-GENE-031116-61
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cxcr7b; sb:cb900; si:dkey-96h14.2
Summary
Enables chemokine binding activity. Acts upstream of or within several processes, including blood vessel morphogenesis; nervous system development; and posterior lateral line neuromast primordium migration. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including anterior neural keel; hindbrain neural keel; immature eye; nervous system; and neural rod. Orthologous to human ACKR3 (atypical chemokine receptor 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See ackr3b in Genome Data Viewer
Location:
chromosome: 6
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (15751977..15757846, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (15625037..15630906, complement)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene tripartite motif containing 63a Neighboring gene uncharacterized LOC137495935 Neighboring gene IQ motif containing with AAA domain 1 Neighboring gene uncharacterized LOC137490186 Neighboring gene Pim proto-oncogene, serine/threonine kinase, related 197

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables C-C chemokine binding  
enables C-C chemokine receptor activity  
enables G protein-coupled receptor activity  
enables chemokine binding  
enables chemokine binding PubMed 
enables coreceptor activity  
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway  
acts_upstream_of_or_within angiogenesis  
acts_upstream_of_or_within angiogenesis PubMed 
involved_in calcium-mediated signaling  
involved_in cell chemotaxis  
acts_upstream_of_or_within chemotaxis  
acts_upstream_of_or_within chemotaxis PubMed 
acts_upstream_of_or_within chemotaxis PubMed 
acts_upstream_of_or_within germ cell migration PubMed 
involved_in immune response  
acts_upstream_of_or_within neuron migration PubMed 
involved_in positive regulation of cytosolic calcium ion concentration  
acts_upstream_of_or_within posterior lateral line neuromast primordium migration PubMed 
acts_upstream_of_or_within posterior lateral line neuromast primordium migration PubMed 
acts_upstream_of_or_within signal transduction  
acts_upstream_of_or_within trigeminal sensory nucleus development PubMed 
acts_upstream_of_or_within trigeminal sensory nucleus development PubMed 
acts_upstream_of_or_within vasculogenesis  
acts_upstream_of_or_within vasculogenesis PubMed 
Component Evidence Code Pubs
is_active_in external side of plasma membrane  
located_in membrane  
located_in plasma membrane  

General protein information

Preferred Names
atypical chemokine receptor 3b
Names
CXCR7
chemokine (C-X-C motif) receptor 7b
chemokine orphan receptor 1
drRDC1b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083832.1NP_001077301.1  atypical chemokine receptor 3b

    See identical proteins and their annotated locations for NP_001077301.1

    Status: PROVISIONAL

    Source sequence(s)
    BC134932
    UniProtKB/TrEMBL
    A0A8M1NDX9, A4IG54
    Related
    ENSDARP00000063664.6, ENSDART00000063665.7
    Conserved Domains (1) summary
    pfam00001
    Location:61314
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    15751977..15757846 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394629.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    196387..201853 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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