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MIRAGE

dolichyldiphosphatase 1

Summary

Gene Symbol

DOLPP1

Aliases

LSFR2
linked to Surfeit genes in Fugu rubripes 2

Organism

Homo sapiens (human)

External Links

NCBI Gene

57171

HGNC

29565

KEGG Gene ID

hsa:57171

PubChem

57171

Alliance of Genome Resources

HGNC:29565

Annotation

Keyword

Alternative splicing
Endoplasmic reticulum
Hydrolase
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q86YN1	Dolichyl pyrophosphate phosphatase 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein N-linked glycosylation	ISS
protein N-linked glycosylation	IBA
dolichyl diphosphate biosynthetic process	TAS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate biosynthetic process

dolichyl diphosphate metabolic process [inference]

dolichyl diphosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate biosynthetic process

dolichyl diphosphate metabolic process [inference]

dolichyl diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate biosynthetic process

dolichyl diphosphate metabolic process [inference]

dolichyl diphosphate biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate biosynthetic process

dolichyl diphosphate metabolic process [inference]

dolichyl diphosphate biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate biosynthetic process

dolichyl diphosphate metabolic process [inference]

dolichyl diphosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate biosynthetic process

dolichyl diphosphate metabolic process [inference]

dolichyl diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate biosynthetic process

dolichyl diphosphate metabolic process [inference]

dolichyl diphosphate biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate biosynthetic process

dolichyl diphosphate metabolic process [inference]

dolichyl diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

dolichyl diphosphate biosynthetic process

dolichyl diphosphate metabolic process [inference]

dolichyl diphosphate biosynthetic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	ISS
endoplasmic reticulum membrane	TAS
endoplasmic reticulum membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
dolichyldiphosphatase activity	ISS
dolichyldiphosphatase activity	TAS
dolichyldiphosphatase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

dolichyldiphosphatase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

phosphatase

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
cellular biosynthetic process
dolichyldiphosphatase activity
hydrolase activity
lipid biosynthetic process
organic substance biosynthetic process
protein N-linked glycosylation

Displaying **all 3** entries
InterPro
Dolichyldiphosphatase, PAP2 domain
Phosphatidic acid phosphatase type 2/haloperoxidase superfamily
Phosphatidic acid phosphatase type 2/haloperoxidase

KEGG BRITE Database

Orthology

K07252

Name

dolichyldiphosphatase [EC:3.6.1.43]

References

Rhea

H₂O

H⁺ + phosphate

Enzyme

3.6.1.43

PMID

Ortholog

Displaying entries **11 - 20** of 79 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Taeniopygia guttata	100218585		TAEGU06496
Pongo abelii	100459417		PONAB36404
Ailuropoda melanoleuca	100464305		AILME16876
Sus scrofa	100516660		PIGXX16313
Meleagris gallopavo	100549946		MELGA05225
Nomascus leucogenys	100601265		NOMLE35849
Loxodonta africana	100658098		LOXAF17020
Oreochromis niloticus	100701662		ORENI65691
Cavia porcellus	100719877		CAVPO12510
Cricetulus griseus	100761712		CRIGR26228

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025