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tumor protein p53 binding protein 1

Summary

Gene Symbol

TP53BP1

Organism

Homo sapiens (human)

External Links

NCBI Gene

7158

PubChem

7158

Alliance of Genome Resources

HGNC:11999

Annotation

Keyword

3D-structure
Activator
Alternative splicing
Centromere
Chromosomal rearrangement
Chromosome
DNA repair
DNA-binding
Host-virus interaction
Isopeptide bond
Kinetochore
Methylation
Nucleus
Phosphoprotein
Reference proteome
Repeat
Transcription regulation
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q12888

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
positive regulation of DNA-binding transcription factor activity	IC	17805299
DNA damage checkpoint signaling	IBA
double-strand break repair via classical nonhomologous end joining	IDA	27153538
cellular response to X-ray	IEA
chromatin organization	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

double-strand break repair via classical nonhomologous end joining

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

double-strand break repair via classical nonhomologous end joining

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

double-strand break repair via classical nonhomologous end joining

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

double-strand break repair via classical nonhomologous end joining

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

double-strand break repair via classical nonhomologous end joining

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

double-strand break repair via classical nonhomologous end joining

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

double-strand break repair via classical nonhomologous end joining

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

double-strand break repair via classical nonhomologous end joining

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

double-strand break repair via classical nonhomologous end joining

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

double-strand break repair via classical nonhomologous end joining

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to site of double-strand break

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

double-strand break repair via classical nonhomologous end joining

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to ionizing radiation [inference]

cellular response to X-ray

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

protein-DNA complex organization [inference]

chromatin organization

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

double-strand break repair via classical nonhomologous end joining

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

response to abiotic stimulus [inference]

response to radiation [inference]

response to ionizing radiation [inference]

response to X-ray [inference]

cellular response to X-ray

cellular response to ionizing radiation [inference]

cellular response to X-ray

cellular response to radiation [inference]

cellular response to ionizing radiation [inference]

cellular response to X-ray

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to ionizing radiation [inference]

cellular response to X-ray

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

DNA repair [inference]

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining

double-strand break repair via classical nonhomologous end joining

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to ionizing radiation [inference]

cellular response to X-ray

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to site of double-strand break

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to site of double-strand break

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

regulation of lymphocyte activation [inference]

regulation of B cell activation [inference]

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of B cell activation [inference]

positive regulation of isotype switching

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of lymphocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of B cell mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of immunoglobulin mediated immune response [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of isotype switching [inference]

positive regulation of isotype switching

regulation of immune response [inference]

regulation of adaptive immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of B cell mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of immunoglobulin mediated immune response [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of isotype switching [inference]

positive regulation of isotype switching

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of DNA repair [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of isotype switching [inference]

positive regulation of isotype switching

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of DNA repair [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of isotype switching [inference]

positive regulation of isotype switching

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of DNA repair [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of isotype switching [inference]

positive regulation of isotype switching

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of DNA repair [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

positive regulation of developmental process [inference]

positive regulation of isotype switching

positive regulation of multicellular organismal process [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

negative regulation of response to stimulus [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

negative regulation of response to stimulus [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of immune response [inference]

regulation of adaptive immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of B cell mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of immunoglobulin mediated immune response [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of DNA repair [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of developmental process [inference]

positive regulation of developmental process [inference]

positive regulation of isotype switching

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of isotype switching [inference]

positive regulation of isotype switching

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of DNA repair [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of transcription by RNA polymerase II

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of DNA recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

regulation of lymphocyte activation [inference]

regulation of B cell activation [inference]

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of B cell activation [inference]

positive regulation of isotype switching

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

regulation of cell cycle phase transition [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

regulation of cellular response to stress [inference]

regulation of DNA repair [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination [inference]

negative regulation of double-strand break repair via homologous recombination

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via homologous recombination

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

regulation of lymphocyte activation [inference]

regulation of B cell activation [inference]

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of B cell activation [inference]

positive regulation of isotype switching

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

positive regulation of multicellular organismal process [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of DNA-binding transcription factor activity

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
site of double-strand break	IDA	22492721 23333306 23760478 27153538 28241136 31135337 32209463 37696958
chromosome, telomeric region	IDA	15149599
nucleoplasm	IDA TAS
nuclear body	IDA
DNA repair complex	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

DNA repair complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

kinetochore

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

kinetochore

site of DNA damage [inference]

site of double-strand break

chromosomal region [inference]

chromosome, telomeric region

supramolecular complex [inference]

kinetochore

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	11877378 12607005 14985081 15456759 16415788 16901786 17024177 17380123 17500065 17525332 17805299 17925232 18001824 18001825 19124460 19433796 20016603 20075863 20126263 20347427 21317870 22373579 22621922 22653443 22884692 23333306 23377543 23760478 25416956 25579814 25651062 25837623 27153538 27462807 28241136 29656893 29789392 32296183 32707033 32814053 34591642
histone reader activity	IDA	23760478 27153538
RNA polymerase II-specific DNA-binding transcription factor binding	IPI	17805299
histone binding	IBA
transcription coregulator activity	IMP	17805299

GO Hierarchy

molecular function

binding [inference]

protein binding

p53 binding

transcription factor binding [inference]

DNA-binding transcription factor binding [inference]

RNA polymerase II-specific DNA-binding transcription factor binding

histone binding

modification-dependent protein binding [inference]

methylation-dependent protein binding [inference]

methylated histone binding

ubiquitination-like modification-dependent protein binding [inference]

ubiquitin-dependent protein binding [inference]

ubiquitin modification-dependent histone binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding [inference]

damaged DNA binding

sequence-specific DNA binding [inference]

telomeric DNA binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

chromatin-protein adaptor activity [inference]

histone reader activity

transcription regulator activity [inference]

transcription coregulator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

uncharacterized protein

Functional Category

K: Transcription
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
histone binding

Displaying **all 4** entries
InterPro
BRCT domain superfamily
BRCT domain
TP53-binding protein 1-like, first BRCT domain
TP53-binding protein 1-like

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:6432	pulmonary hypertension	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 72 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	27223		MGI:1351320	MOUSE32418
Rattus norvegicus	296099		RGD:1308039	RATNO28330
Xenopus laevis	398208		Xenbase:XB-GENE-1010618
Pan troglodytes	467668	9598_0:003ee0		PANTR10140
Canis lupus familiaris	478274			CANLF12452
Bos taurus	509111			BOVIN16844
Danio rerio	557086		ZFIN:ZDB-GENE-030131-3695	DANRE41626
Macaca mulatta	710237			MACMU42132
Saccharomyces cerevisiae S288C	851803		SGD:S000002625
Caenorhabditis elegans	3565010		WB:WBGene00002027

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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Annotation

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Acknowledgements