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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2
Summary
- Gene Symbol
-
- PREX2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Guanine-nucleotide releasing factor
- Reference proteome
- Repeat
- Proteins
| UniProt | Protein Name |
|---|---|
| Q70Z35 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of small GTPase mediated signal transduction | ||
| phosphatidylinositol 3-kinase/protein kinase B signal transduction | ||
| dendrite morphogenesis | ||
| regulation of signaling | ||
| adult locomotory behavior |
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| cytosol |
| GO Term | Evidence Code | PMID |
|---|---|---|
| GTPase activator activity | ||
| guanyl-nucleotide exchange factor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Leucine rich repeat
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
Disease
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 109294 | MGI:1923385 | MOUSE27539 | ||
| 312912 | RGD:1307865 | RATNO32897 | ||
| 464222 | 9598_0:002672 | PANTR42717 | ||
| 486984 | CANLF11704 | |||
| 557288 | ZFIN:ZDB-GENE-091113-37 | DANRE26410 | ||
| 705243 | MACMU44317 | |||
| 100028912 | MONDO19399 | |||
| 100063148 | HORSE42945 | |||
| 100080403 | ORNAN25330 | |||
| 100225928 | TAEGU18835 |
