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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
acetylcholinesterase
Summary
- Gene Symbol
-
- Ache
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Disulfide bond
- GPI-anchor
- Neurotransmitter degradation
- Reference proteome
- Secreted
- Serine esterase
- Signal
- Synapse
- Proteins
| UniProt | Protein Name |
|---|---|
| P37136 |
|
| A0A9K3Y822 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| acetylcholine receptor signaling pathway | ||
| synapse assembly | ||
| acetylcholine catabolic process in synaptic cleft |
|
|
| receptor internalization | ||
| acetylcholine catabolic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| membrane | ||
| postsynaptic membrane | ||
| Golgi apparatus | ||
| terminal bouton |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| hydrolase activity | ||
| choline binding | ||
| cholinesterase activity | ||
| identical protein binding | ||
| serine hydrolase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- acetylcholinesterase
- Functional Category
-
- E: Amino acid transport and metabolism
- P: Inorganic ion transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| acetylcholine catabolic process |
| acetylcholinesterase activity |
| choline metabolic process |
| cholinesterase activity |
| hydrolase activity |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10487 | Hirschsprung's disease | |
| DOID:10652 | Alzheimer's disease | |
| DOID:12858 | Huntington's disease | |
| DOID:14330 | Parkinson's disease | |
| DOID:1826 | epilepsy | |
| DOID:1849 | cannabis dependence | |
| DOID:2297 | leptospirosis | |
| DOID:2377 | multiple sclerosis | |
| DOID:437 | myasthenia gravis | |
| DOID:6088 | acute stress disorder |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 43 | HGNC:108 | HUMAN90422 | ||
| 11423 | 10090_1:0016c6 | MGI:87876 | MOUSE47297 | |
| 41625 | FB:FBgn0000024 | |||
| 114549 | ZFIN:ZDB-GENE-010906-1 | DANRE41472 | ||
| 175074 | WB:WBGene00000038 | |||
| 181706 | WB:WBGene00000035 | |||
| 489828 | CANLF16192 | |||
| 493674 | FELCA35129 | |||
| 540446 | BOVIN20838 | |||
| 713370 | MACMU31141 |
