Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
diacylglycerol O-acyltransferase 1
Summary
- Gene Symbol
-
- DGAT1
- Aliases
-
- ARGP1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acyltransferase
- Disease variant
- Endoplasmic reticulum
- Lipid metabolism
- Phosphoprotein
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| O75907 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| long-chain fatty-acyl-CoA metabolic process | ||
| diacylglycerol metabolic process | ||
| lipid storage | ||
| retinol metabolic process |
GO Hierarchy
biological process
metabolic process [inference]
nitrogen compound metabolic process [inference]
cellular metabolic process [inference]
primary metabolic process [inference]
small molecule metabolic process [inference]
organic substance metabolic process [inference]
cellular process [inference]
cellular metabolic process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum membrane | ||
| plasma membrane |
|
|
| membrane | ||
| specific granule membrane |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| diacylglycerol O-acyltransferase activity | ||
| 2-acylglycerol O-acyltransferase activity | ||
| acyltransferase activity |
|
|
| protein binding | ||
| retinol O-fatty-acyltransferase activity |
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0014667 | disease of metabolism | |
| DOID:0050700 | cardiomyopathy | |
| DOID:0050729 | Chanarin-Dorfman syndrome | |
| DOID:0060357 | chylomicron retention disease | |
| DOID:0060656 | autosomal recessive congenital ichthyosis 1 | |
| DOID:0060775 | microvillus inclusion disease | |
| DOID:0060776 | congenital diarrhea 5 with tufting enteropathy | |
| DOID:0060777 | congenital secretory sodium diarrhea 8 | |
| DOID:0060778 | congenital diarrhea 7 with exudative enteropathy | |
| DOID:0060779 | congenital malabsorptive diarrhea 4 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0001508 | Failure to thrive |
| HP:0002013 | Vomiting |
| HP:0002014 | Diarrhea |
| HP:0002243 | Protein-losing enteropathy |
| HP:0003073 | Hypoalbuminemia |
| HP:0003077 | Hyperlipidemia |
| HP:0003124 | Hypercholesterolemia |
| HP:0003623 | Neonatal onset |
| HP:0011473 | Villous atrophy |
| Disease ID | Disease Name |
|---|---|
| OMIM:615863 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP006743
- Gene Name
- diacylglycerol O-acyltransferase 1
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 397118 | PIGXX22688 | ||
| 282609 | BOVIN05540 | ||
| 100861225 | CAPHI05036 | ||
| 13350 | MGI:1333825 | MOUSE16433 | |
| 84497 | RGD:628673 | ||
| 100733854 | CAVPO21578 | ||
| 101575480 | OCTDE17528 | ||
| 100018271 | MONDO19133 | ||
| 114039859 | VOMUR26604 | ||
| 100961287 | OTOGA01368 |
