GlyCosmos Portal

Displaying **all 3** entries
GO Term	Evidence Code	PMID
lactosylceramide alpha-2,3-sialyltransferase activity	IBA IDA	9822625
beta-galactoside (CMP) alpha-2,3-sialyltransferase activity	TAS
sialyltransferase activity	TAS	10092602

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

sialyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000115525

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlycoGene Database (GGDB)

GGDB ID

gg052

Gene Symbol

ST3GAL5

Reactions

Displaying 1 entry
Donor	Acceptor	Product	Reference
CMP-Neu5Ac	G84224TW	G91237TK	9822625

Displaying 1 entry
Donor	Acceptor	Product	Reference
CMP-Neu5Ac	G84224TW	G91237TK	9822625

Orthologous Gene

Displaying **all 2** entries
Species	Protein	mRNA
Rattus norvegicus	NP_112627	NM_031337
Mus musculus	NP_035505	NM_011375

KEGG BRITE Database

Orthology

K03370

Name

lactosylceramide alpha-2,3-sialyltransferase (sialyltransferase 9) [EC:2.4.3.9]

References

9875239

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05937	2.4.3.9	G84224TW	G91237TK

Rhea

RHEA:18417

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + CMP-N-acetyl-β-neuraminate

H⁺ + a ganglioside GM3 (d18:1(4E)) + CMP

Enzyme

2.4.3.9

PMID

Disease

Disease Ontology

Displaying entries **51 - 60** of **105** in total

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DO ID	Disease Name	Source
DOID:0110805	hereditary spastic paraplegia 53	DisGeNET
DOID:0110806	hereditary spastic paraplegia 54	DisGeNET
DOID:0110807	hereditary spastic paraplegia 55	DisGeNET
DOID:0110808	hereditary spastic paraplegia 56	DisGeNET
DOID:0110809	hereditary spastic paraplegia 57	DisGeNET
DOID:0110810	hereditary spastic paraplegia 5A	DisGeNET
DOID:0110811	hereditary spastic paraplegia 6	DisGeNET
DOID:0110812	hereditary spastic paraplegia 61	DisGeNET
DOID:0110813	hereditary spastic paraplegia 62	DisGeNET
DOID:0110814	hereditary spastic paraplegia 63	DisGeNET

The Human Phenotype Ontology

Displaying entries **21 - 26** of 26 in total

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HPO ID	HPO Term
HP:0003623	Neonatal onset
HP:0006834	Developmental stagnation at onset of seizures
HP:0008872	Feeding difficulties in infancy
HP:0010841	Multifocal epileptiform discharges
HP:0012391	Hyporeflexia of upper limbs
HP:0100704	Cerebral visual impairment

Displaying 1 entry
Disease ID	Disease Name
OMIM:609056	GM3 synthase deficiency

PubChem Disease

GHR Health Conditions

GM3 synthase deficiency

MedGen Diseases

GM3 synthase deficiency

OMIM Phenotypes

SALT AND PEPPER DEVELOPMENTAL REGRESSION SYNDROME; SPDRS

KEGG Diseases

Amish infantile epilepsy syndrome

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP000401
Gene Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 5

Ortholog

Displaying entries **1 - 10** of 81 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Latimeria chalumnae	102352419		LATCH08468
Danio rerio	394230	ZFIN:ZDB-GENE-060322-1	DANRE06942
Ictalurus punctatus	108269097		ICTPU33590
Electrophorus electricus	113584806		ELEEL34418
Salmo trutta	115205504		SALTR111690
Gadus morhua	115552722		GADMO02518
Oryzias latipes	101156587		ORYLA01383
Xenopus laevis	108697625	Xenbase:XB-GENE-17345694
Xenopus laevis	108706512	Xenbase:XB-GENE-17345695
Xenopus tropicalis	100329191	Xenbase:XB-GENE-955106

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

GlycoGene Database (GGDB)

KEGG BRITE Database

PubChem Disease

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements