GlyCosmos Portal

Displaying **all 3** entries
GO Term	Evidence Code	PMID
lactosylceramide alpha-2,3-sialyltransferase activity	IBA IDA	9822625
beta-galactoside (CMP) alpha-2,3-sialyltransferase activity	TAS
sialyltransferase activity	TAS	10092602

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

sialyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000115525

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlycoGene Database (GGDB)

GGDB ID

gg052

Gene Symbol

ST3GAL5

Reactions

Displaying 1 entry
Donor	Acceptor	Product	Reference
CMP-Neu5Ac	G84224TW	G91237TK	9822625

Displaying 1 entry
Donor	Acceptor	Product	Reference
CMP-Neu5Ac	G84224TW	G91237TK	9822625

Orthologous Gene

Displaying **all 2** entries
Species	Protein	mRNA
Rattus norvegicus	NP_112627	NM_031337
Mus musculus	NP_035505	NM_011375

KEGG BRITE Database

Orthology

K03370

Name

lactosylceramide alpha-2,3-sialyltransferase (sialyltransferase 9) [EC:2.4.3.9]

References

9875239

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05937	2.4.3.9	G84224TW	G91237TK

Rhea

RHEA:18417

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + CMP-N-acetyl-β-neuraminate

H⁺ + a ganglioside GM3 (d18:1(4E)) + CMP

Enzyme

2.4.3.9

PMID

Disease

Disease Ontology

Displaying entries **51 - 60** of **105** in total

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DO ID	Disease Name	Source
DOID:0110805	hereditary spastic paraplegia 53	DisGeNET
DOID:0110806	hereditary spastic paraplegia 54	DisGeNET
DOID:0110807	hereditary spastic paraplegia 55	DisGeNET
DOID:0110808	hereditary spastic paraplegia 56	DisGeNET
DOID:0110809	hereditary spastic paraplegia 57	DisGeNET
DOID:0110810	hereditary spastic paraplegia 5A	DisGeNET
DOID:0110811	hereditary spastic paraplegia 6	DisGeNET
DOID:0110812	hereditary spastic paraplegia 61	DisGeNET
DOID:0110813	hereditary spastic paraplegia 62	DisGeNET
DOID:0110814	hereditary spastic paraplegia 63	DisGeNET

The Human Phenotype Ontology

Displaying entries **1 - 10** of 26 in total

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HPO ID	HPO Term
HP:0000007	Autosomal recessive inheritance
HP:0000252	Microcephaly
HP:0000365	Hearing impairment
HP:0000572	Visual loss
HP:0000648	Optic atrophy
HP:0000737	Irritability
HP:0001034	Hypermelanotic macule
HP:0001252	Hypotonia
HP:0001263	Global developmental delay
HP:0001266	Choreoathetosis

Displaying 1 entry
Disease ID	Disease Name
OMIM:609056	GM3 synthase deficiency

PubChem Disease

GHR Health Conditions

GM3 synthase deficiency

MedGen Diseases

GM3 synthase deficiency

OMIM Phenotypes

SALT AND PEPPER DEVELOPMENTAL REGRESSION SYNDROME; SPDRS

KEGG Diseases

Amish infantile epilepsy syndrome

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP000401
Gene Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 5

Ortholog

Displaying entries **51 - 60** of 81 in total

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Species	Gene ID	Orthologous MAtrix
Pelodiscus sinensis	102453544	PELSI11095
Anolis carolinensis	100561853	ANOCA14281
Ursus maritimus	103671460	URSMA00494
Vombatus ursinus	114041817	VOMUR29761
Bos indicus x Bos taurus	113901305	BOBOX20203
Otolemur garnettii	100951715	OTOGA04099
Takifugu rubripes	777948	TAKRU09708
Chinchilla lanigera	102024023	CHILA07609
Aotus nancymaae	105731265	AOTNA35009
Saimiri boliviensis boliviensis	101033571	SAIBB36697

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

GlycoGene Database (GGDB)

KEGG BRITE Database

PubChem Disease

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements