GlyCosmos Portal

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
DNA binding	IBA
DNA N-glycosylase activity	TAS
satellite DNA binding	TAS	9774669
pyrimidine-specific mismatch base pair DNA N-glycosylase activity	IDA	14614141
DNA endonuclease activity	TAS	10097147

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

nuclease activity [inference]

endonuclease activity [inference]

DNA endonuclease activity

DNA nuclease activity [inference]

DNA endonuclease activity

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

DNA N-glycosylase activity

mismatch base pair DNA N-glycosylase activity [inference]

pyrimidine-specific mismatch base pair DNA N-glycosylase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

DNA nuclease activity [inference]

DNA endonuclease activity

DNA N-glycosylase activity

mismatch base pair DNA N-glycosylase activity [inference]

pyrimidine-specific mismatch base pair DNA N-glycosylase activity

binding [inference]

protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding

double-stranded DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

satellite DNA binding

sequence-specific DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

satellite DNA binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000129071

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

Disease

Disease Ontology

Displaying entries **11 - 20** of 71 in total

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DO ID	Disease Name	Source
DOID:1325	bronchus cancer	DisGeNET
DOID:13375	temporal arteritis	DisGeNET
DOID:13399	color blindness	DisGeNET
DOID:13608	biliary atresia	DisGeNET DisGeNET
DOID:1380	endometrial cancer	DisGeNET DisGeNET
DOID:13909	red-green color blindness	DisGeNET
DOID:13910	red color blindness	DisGeNET
DOID:13911	achromatopsia	DisGeNET
DOID:13912	acquired color blindness	DisGeNET
DOID:1520	colon carcinoma	DisGeNET

The Human Phenotype Ontology

Displaying entries **1 - 10** of 11 in total

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HPO ID	HPO Term
HP:0000006	Autosomal dominant inheritance
HP:0002858	Meningioma
HP:0003003	Colon cancer
HP:0003581	Adult onset
HP:0003596	Middle age onset
HP:0003621	Juvenile onset
HP:0004808	Acute myeloid leukemia
HP:0005227	Adenomatous colonic polyposis
HP:0007716	Uveal melanoma
HP:0011462	Young adult onset

Displaying **all 2** entries
Disease ID	Disease Name
OMIM:619975	tumor predisposition syndrome 2
OMIM:606660	melanoma, uveal, susceptibility to, 1

PubChem Disease

MedGen Diseases

OMIM Phenotypes

KEGG Diseases

Tumor predisposition syndrome

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

Ortholog

Displaying entries **31 - 40** of 44 in total

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Species	Gene ID	Orthologous MAtrix
Bos indicus x Bos taurus	113880637	BOBOX09267
Microcebus murinus	105882683	MICMU08817
Otolemur garnettii	100966492	OTOGA06606
Chinchilla lanigera	102012986	CHILA08684
Saimiri boliviensis boliviensis	101047975	SAIBB10472
Ictidomys tridecemlineatus	101971631	ICTTR08633
Myotis lucifugus	102432161	MYOLU01825
Rhinolophus ferrumequinum	117036549	RHIFE16732
Chlorocebus sabaeus	103228069	CHLSB10610
Rhinopithecus bieti	108537514	RHIBE03833

ChIP-Atlas

Target Genes: Predicted target genes bound by given transcription factors. Target Genes
Potential target genes for MBD4
Distance from TSS: ± 10 kb

Displaying entries **91 - 100** of **148** in total

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Gene Symbol	Description	Cellline (score)
B3GNT2	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Hep_G2(208)
ALG9	ALG9 alpha-1,2-mannosyltransferase	Hep_G2(98)
SACM1L	SAC1 like phosphatidylinositide phosphatase	Hep_G2(204)
MOGS	mannosyl-oligosaccharide glucosidase	Hep_G2(425)
MGAT5	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Hep_G2(104)
HIBCH	3-hydroxyisobutyryl-CoA hydrolase	Hep_G2(235)
DCTD	dCMP deaminase	Hep_G2(258)
NANP	N-acetylneuraminic acid phosphatase	Hep_G2(115)
PIGZ	phosphatidylinositol glycan anchor biosynthesis class Z	Hep_G2(197)
PFKFB4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	Hep_G2(132)

Colocalization: Predicted partner proteins colocalizing with given transcription factors. Colocalization
Colocalization analysis for MBD4

Displaying 1 entry
Gene Symbol	Description	Cellline (score)
MBD4	methyl-CpG binding domain 4, DNA glycosylase	Hep_G2(10)

An integrative, comprehensive database to explore public Epigenetic dataset, including ChIP-Seq, DNase-Seq, ATAC-Seq, and Bisulfite-Seq data: ChIP-Atlas covers almost all public data archived in Sequence Read Archive of NCBI, EBI, and DDBJ with over 224,000 experiments.

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

PubChem Disease

International Collaboration

Acknowledgements