GlyCosmos Portal

GlyCosmos Genes

Integrated list of glycan-related genes extracted KEGG GENES Database, UniProt, GlycoGene Database (GGDB), Plant GARDEN and FlyGlycoDB. Glycan-related genes including glycosyltransferase, hydrolase activity (acting on glycosyl bonds), carbohydrate metabolic process, etc .

Source	Last Updated
FlyGlycoDB	March 25, 2024
GlycoGene Database (GGDB)	January 26, 2018
KEGG GENES Database	September 20, 2023
Plant GARDEN	May 28, 2020
UniProt	October 29, 2024

Selecting the function you want to look up from the categories displays a list narrowed down to glycan-related genes with that function (Gene Ontology).

Catalytic activity

glycosyltransferase activity

hydrolase activity, acting on glycosyl bonds

Binding

carbohydrate binding

Response to carbohydrate

Primary metabolic process

Displaying entries **51 - 75** of **9988** in total

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Gene ID ▲	Gene Name	Gene Symbol	Organism	Taxonomy ID	Disease Ontology	Disease Ontology ID	Gene Ontology	Gene Ontology ID
93	activin A receptor type 2B	ACVR2B	Homo sapiens (human)	9606			ATP binding BMP signaling pathway activin binding activin receptor activity, type II activin receptor activity activin receptor complex activin receptor signaling pathway adenyl nucleotide binding adenyl ribonucleotide binding amide transport anatomical structure development anatomical structure formation involved in morphogenesis anatomical structure morphogenesis animal organ development animal organ morphogenesis anion binding anterior/posterior pattern specification artery development binding biological regulation biological_process blood vessel development blood vessel remodeling carbohydrate derivative binding catalytic activity, acting on a protein catalytic activity catalytic complex cation binding cell differentiation cell surface receptor signaling pathway cellular anatomical entity cellular developmental process cellular localization cellular macromolecule localization cellular metabolic process cellular process cellular response to endogenous stimulus cellular response to growth factor stimulus cellular_component cytoplasm determination of bilateral symmetry determination of left/right symmetry developmental growth developmental process embryonic foregut morphogenesis embryonic morphogenesis endothelial cell differentiation enzyme activator activity enzyme regulator activity enzyme-linked receptor protein signaling pathway epithelial cell differentiation establishment of localization establishment of protein localization to extracellular region establishment of protein localization export from cell gastrulation with mouth forming second gastrulation growth factor binding growth heart development heterocyclic compound binding hormone secretion hormone transport insulin secretion ion binding kidney development kinase activator activity kinase activity kinase regulator activity localization lung development lymphangiogenesis lymphatic endothelial cell differentiation macromolecule localization macromolecule metabolic process macromolecule modification membrane protein complex membrane mesoderm development metabolic process metal ion binding molecular function activator activity molecular function regulator activity molecular transducer activity molecular_function multicellular organismal process negative regulation of DNA-templated transcription negative regulation of RNA biosynthetic process negative regulation of RNA metabolic process negative regulation of biological process negative regulation of biosynthetic process negative regulation of cellular biosynthetic process negative regulation of cellular metabolic process negative regulation of cellular process negative regulation of cold-induced thermogenesis negative regulation of macromolecule biosynthetic process negative regulation of macromolecule metabolic process negative regulation of metabolic process negative regulation of multicellular organismal process negative regulation of nitrogen compound metabolic process negative regulation of nucleobase-containing compound metabolic process negative regulation of transcription by RNA polymerase II nitrogen compound metabolic process nitrogen compound transport nucleoside phosphate binding nucleotide binding odontogenesis of dentin-containing tooth odontogenesis organ growth organic cyclic compound binding organic substance metabolic process organic substance transport organonitrogen compound metabolic process pancreas development pattern specification process peptide hormone secretion peptide secretion peptide transport phosphate-containing compound metabolic process phosphorus metabolic process phosphorylation phosphotransferase activity, alcohol group as acceptor plasma membrane protein complex plasma membrane signaling receptor complex plasma membrane positive regulation of activin receptor signaling pathway positive regulation of biological process positive regulation of biomineral tissue development positive regulation of bone mineralization positive regulation of cell communication positive regulation of cell differentiation positive regulation of cellular process positive regulation of developmental process positive regulation of multicellular organismal process positive regulation of ossification positive regulation of osteoblast differentiation positive regulation of response to stimulus positive regulation of signal transduction positive regulation of signaling positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway post-embryonic development primary metabolic process protein binding protein kinase activity protein kinase complex protein localization to extracellular region protein localization protein metabolic process protein modification process protein phosphorylation protein secretion protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein transport protein-containing complex binding protein-containing complex purine nucleotide binding purine ribonucleoside triphosphate binding purine ribonucleotide binding receptor complex regionalization regulation of DNA-templated transcription regulation of RNA biosynthetic process regulation of RNA metabolic process regulation of activin receptor signaling pathway regulation of biological process regulation of biological quality regulation of biomineral tissue development regulation of biosynthetic process regulation of bone mineralization regulation of cell communication regulation of cell differentiation regulation of cellular biosynthetic process regulation of cellular metabolic process regulation of cellular process regulation of cold-induced thermogenesis regulation of developmental process regulation of gene expression regulation of hormone levels regulation of macromolecule biosynthetic process regulation of macromolecule metabolic process regulation of metabolic process regulation of multicellular organismal development regulation of multicellular organismal process regulation of nitrogen compound metabolic process regulation of nucleobase-containing compound metabolic process regulation of ossification regulation of osteoblast differentiation regulation of primary metabolic process regulation of response to stimulus regulation of signal transduction regulation of signaling regulation of transcription by RNA polymerase II regulation of transmembrane receptor protein serine/threonine kinase signaling pathway response to carbohydrate response to chemical response to endogenous stimulus response to glucose response to growth factor response to hexose response to monosaccharide response to organic substance response to oxygen-containing compound response to stimulus retina vasculature development in camera-type eye ribonucleotide binding roof of mouth development secretion by cell secretion serine/threonine protein kinase complex signal release signal transduction signaling receptor activity skeletal system morphogenesis small molecule binding specification of symmetry system development tissue development tissue remodeling transferase activity, transferring phosphorus-containing groups transferase activity transferase complex, transferring phosphorus-containing groups transferase complex transforming growth factor beta receptor activity transforming growth factor beta receptor superfamily signaling pathway transmembrane receptor protein kinase activity transmembrane receptor protein serine/threonine kinase activity transmembrane receptor protein serine/threonine kinase signaling pathway transmembrane signaling receptor activity transport vasculature development venous blood vessel development	GO:0000122 GO:0000166 GO:0001568 GO:0001702 GO:0001822 GO:0001944 GO:0001946 GO:0001974 GO:0002790 GO:0003002 GO:0003674 GO:0003824 GO:0004672 GO:0004674 GO:0004675 GO:0004712 GO:0004888 GO:0005024 GO:0005488 GO:0005515 GO:0005524 GO:0005575 GO:0005737 GO:0005886 GO:0006355 GO:0006357 GO:0006468 GO:0006793 GO:0006796 GO:0006807 GO:0006810 GO:0007165 GO:0007166 GO:0007167 GO:0007178 GO:0007368 GO:0007369 GO:0007389 GO:0007498 GO:0007507 GO:0008047 GO:0008104 GO:0008150 GO:0008152 GO:0009306 GO:0009653 GO:0009719 GO:0009743 GO:0009746 GO:0009749 GO:0009791 GO:0009799 GO:0009855 GO:0009887 GO:0009888 GO:0009889 GO:0009890 GO:0009892 GO:0009914 GO:0009952 GO:0009966 GO:0009967 GO:0009987 GO:0010033 GO:0010468 GO:0010556 GO:0010558 GO:0010605 GO:0010646 GO:0010647 GO:0010817 GO:0015031 GO:0015833 GO:0016020 GO:0016301 GO:0016310 GO:0016362 GO:0016740 GO:0016772 GO:0016773 GO:0017002 GO:0017076 GO:0019199 GO:0019207 GO:0019209 GO:0019219 GO:0019222 GO:0019538 GO:0019838 GO:0023051 GO:0023056 GO:0023061 GO:0030072 GO:0030073 GO:0030154 GO:0030234 GO:0030278 GO:0030324 GO:0030500 GO:0030501 GO:0030509 GO:0030554 GO:0030855 GO:0031016 GO:0031323 GO:0031324 GO:0031326 GO:0031327 GO:0032501 GO:0032502 GO:0032553 GO:0032555 GO:0032559 GO:0032924 GO:0032925 GO:0032927 GO:0032940 GO:0032991 GO:0033036 GO:0034284 GO:0035265 GO:0035592 GO:0035639 GO:0036094 GO:0036211 GO:0038023 GO:0040007 GO:0042221 GO:0042475 GO:0042476 GO:0042886 GO:0043167 GO:0043168 GO:0043169 GO:0043170 GO:0043235 GO:0043412 GO:0044237 GO:0044238 GO:0044877 GO:0045184 GO:0045446 GO:0045595 GO:0045597 GO:0045667 GO:0045669 GO:0045778 GO:0045892 GO:0045934 GO:0046872 GO:0046879 GO:0046903 GO:0048179 GO:0048185 GO:0048513 GO:0048518 GO:0048519 GO:0048522 GO:0048523 GO:0048583 GO:0048584 GO:0048589 GO:0048598 GO:0048617 GO:0048646 GO:0048705 GO:0048731 GO:0048771 GO:0048856 GO:0048869 GO:0050789 GO:0050793 GO:0050794 GO:0050896 GO:0051094 GO:0051171 GO:0051172 GO:0051179 GO:0051234 GO:0051239 GO:0051240 GO:0051241 GO:0051252 GO:0051253 GO:0051641 GO:0060021 GO:0060089 GO:0060255 GO:0060836 GO:0060840 GO:0060841 GO:0061298 GO:0061695 GO:0065007 GO:0065008 GO:0070167 GO:0070169 GO:0070727 GO:0070848 GO:0071363 GO:0071495 GO:0071692 GO:0071702 GO:0071704 GO:0071705 GO:0080090 GO:0090092 GO:0090100 GO:0097159 GO:0097367 GO:0098772 GO:0098796 GO:0098797 GO:0098802 GO:0110165 GO:0120161 GO:0120163 GO:0140096 GO:0140352 GO:0140677 GO:0141091 GO:1901265 GO:1901363 GO:1901564 GO:1901700 GO:1902494 GO:1902554 GO:1902679 GO:1902911 GO:1990234 GO:2000026 GO:2001141
94	activin A receptor like type 1	ACVRL1	Homo sapiens (human)	9606			ATP binding BMP receptor activity BMP receptor complex BMP signaling pathway SMAD binding activin binding activin receptor activity, type I activin receptor activity activin receptor signaling pathway adenyl nucleotide binding adenyl ribonucleotide binding anatomical structure development anatomical structure formation involved in morphogenesis anatomical structure maturation anatomical structure morphogenesis angiogenesis animal organ development anion binding aorta morphogenesis artery development artery morphogenesis binding biological regulation biological_process blood circulation blood vessel development blood vessel endothelial cell proliferation involved in sprouting angiogenesis blood vessel maturation blood vessel morphogenesis blood vessel remodeling carbohydrate derivative binding cardiac epithelial to mesenchymal transition catalytic activity, acting on a protein catalytic activity cation binding cell body cell differentiation cell migration cell motility cell population proliferation cell projection cell surface receptor signaling pathway cell surface cellular anatomical entity cellular developmental process cellular metabolic process cellular process cellular response to BMP stimulus cellular response to endogenous stimulus cellular response to growth factor stimulus cellular response to transforming growth factor beta stimulus cellular_component chordate embryonic development circulatory system process cytokine binding dendrite developmental maturation developmental process dorsal aorta morphogenesis dorsal/ventral pattern formation embryo development ending in birth or egg hatching embryo development endocardial cushion morphogenesis endocardial cushion to mesenchymal transition endothelial cell differentiation endothelial cell proliferation endothelial tube morphogenesis enzyme binding enzyme-linked receptor protein signaling pathway epithelial cell differentiation epithelial cell proliferation epithelial to mesenchymal transition epithelial tube morphogenesis growth factor binding heart development heterocyclic compound binding in utero embryonic development ion binding kinase activity kinase binding lymphangiogenesis lymphatic endothelial cell differentiation macromolecule metabolic process macromolecule modification membrane protein complex membrane mesenchymal cell differentiation mesenchyme morphogenesis metabolic process metal ion binding molecular transducer activity molecular_function morphogenesis of an endothelium morphogenesis of an epithelium multicellular organism development multicellular organismal process negative regulation of biological process negative regulation of biosynthetic process negative regulation of blood vessel endothelial cell migration negative regulation of cell adhesion negative regulation of cell differentiation negative regulation of cell growth negative regulation of cell junction assembly negative regulation of cell migration negative regulation of cell motility negative regulation of cell population proliferation negative regulation of cell-matrix adhesion negative regulation of cell-substrate adhesion negative regulation of cell-substrate junction organization negative regulation of cellular biosynthetic process negative regulation of cellular component organization negative regulation of cellular metabolic process negative regulation of cellular process negative regulation of developmental process negative regulation of endothelial cell differentiation negative regulation of endothelial cell migration negative regulation of endothelial cell proliferation negative regulation of epithelial cell differentiation negative regulation of epithelial cell migration negative regulation of epithelial cell proliferation negative regulation of focal adhesion assembly negative regulation of gene expression negative regulation of growth negative regulation of locomotion negative regulation of macromolecule biosynthetic process negative regulation of macromolecule metabolic process negative regulation of metabolic process negative regulation of multicellular organismal process neuron projection neuronal cell body nitrogen compound metabolic process nucleoside phosphate binding nucleotide binding organic cyclic compound binding organic substance metabolic process organonitrogen compound metabolic process pattern specification process phosphate-containing compound metabolic process phosphorus metabolic process phosphorylation phosphotransferase activity, alcohol group as acceptor plasma membrane bounded cell projection plasma membrane protein complex plasma membrane signaling receptor complex plasma membrane positive regulation of BMP signaling pathway positive regulation of DNA-templated transcription positive regulation of Notch signaling pathway positive regulation of RNA biosynthetic process positive regulation of RNA metabolic process positive regulation of SMAD protein signal transduction positive regulation of angiogenesis positive regulation of bicellular tight junction assembly positive regulation of biological process positive regulation of biosynthetic process positive regulation of cartilage development positive regulation of cell communication positive regulation of cell differentiation positive regulation of cell junction assembly positive regulation of cell population proliferation positive regulation of cellular biosynthetic process positive regulation of cellular component biogenesis positive regulation of cellular component organization positive regulation of cellular metabolic process positive regulation of cellular process positive regulation of chondrocyte differentiation positive regulation of developmental process positive regulation of endothelial cell differentiation positive regulation of endothelial cell proliferation positive regulation of epithelial cell differentiation positive regulation of epithelial cell proliferation positive regulation of intracellular signal transduction positive regulation of macromolecule biosynthetic process positive regulation of macromolecule metabolic process positive regulation of metabolic process positive regulation of multicellular organismal process positive regulation of nitrogen compound metabolic process positive regulation of nucleobase-containing compound metabolic process positive regulation of response to stimulus positive regulation of signal transduction positive regulation of signaling positive regulation of transcription by RNA polymerase II positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway positive regulation of vasculature development primary metabolic process protein binding protein kinase activity protein kinase binding protein metabolic process protein modification process protein phosphorylation protein serine/threonine kinase activity protein-containing complex binding protein-containing complex purine nucleotide binding purine ribonucleoside triphosphate binding purine ribonucleotide binding receptor complex regionalization regulation of BMP signaling pathway regulation of DNA metabolic process regulation of DNA replication regulation of DNA-templated transcription regulation of Notch signaling pathway regulation of RNA biosynthetic process regulation of RNA metabolic process regulation of SMAD protein signal transduction regulation of anatomical structure morphogenesis regulation of angiogenesis regulation of bicellular tight junction assembly regulation of biological process regulation of biological quality regulation of biosynthetic process regulation of blood pressure regulation of blood vessel endothelial cell migration regulation of cartilage development regulation of cell adhesion regulation of cell communication regulation of cell differentiation regulation of cell growth regulation of cell junction assembly regulation of cell migration regulation of cell motility regulation of cell population proliferation regulation of cell-matrix adhesion regulation of cell-substrate adhesion regulation of cell-substrate junction assembly regulation of cell-substrate junction organization regulation of cellular biosynthetic process regulation of cellular component biogenesis regulation of cellular component organization regulation of cellular metabolic process regulation of cellular process regulation of cellular response to growth factor stimulus regulation of chondrocyte differentiation regulation of developmental process regulation of endothelial cell differentiation regulation of endothelial cell migration regulation of endothelial cell proliferation regulation of epithelial cell differentiation regulation of epithelial cell migration regulation of epithelial cell proliferation regulation of focal adhesion assembly regulation of gene expression regulation of growth regulation of intracellular signal transduction regulation of locomotion regulation of macromolecule biosynthetic process regulation of macromolecule metabolic process regulation of metabolic process regulation of multicellular organismal development regulation of multicellular organismal process regulation of nitrogen compound metabolic process regulation of nucleobase-containing compound metabolic process regulation of primary metabolic process regulation of response to stimulus regulation of signal transduction regulation of signaling regulation of transcription by RNA polymerase II regulation of transmembrane receptor protein serine/threonine kinase signaling pathway regulation of vasculature development response to BMP response to abiotic stimulus response to decreased oxygen levels response to endogenous stimulus response to growth factor response to hypoxia response to oxygen levels response to stimulus response to stress response to transforming growth factor beta retina vasculature development in camera-type eye ribonucleotide binding signal transduction signaling receptor activity small molecule binding system development system process tissue morphogenesis tissue remodeling transferase activity, transferring phosphorus-containing groups transferase activity transforming growth factor beta binding transforming growth factor beta receptor activity, type I transforming growth factor beta receptor activity transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor superfamily signaling pathway transmembrane receptor protein kinase activity transmembrane receptor protein serine/threonine kinase activity transmembrane receptor protein serine/threonine kinase signaling pathway transmembrane signaling receptor activity tube morphogenesis vasculature development venous blood vessel development wound healing, spreading of cells wound healing, spreading of epidermal cells	GO:0000166 GO:0001525 GO:0001558 GO:0001568 GO:0001666 GO:0001701 GO:0001837 GO:0001935 GO:0001936 GO:0001937 GO:0001938 GO:0001944 GO:0001946 GO:0001952 GO:0001953 GO:0001955 GO:0001974 GO:0002009 GO:0002043 GO:0003002 GO:0003008 GO:0003013 GO:0003159 GO:0003203 GO:0003674 GO:0003824 GO:0004672 GO:0004674 GO:0004675 GO:0004888 GO:0005024 GO:0005025 GO:0005488 GO:0005515 GO:0005524 GO:0005575 GO:0005886 GO:0006275 GO:0006355 GO:0006357 GO:0006468 GO:0006793 GO:0006796 GO:0006807 GO:0006950 GO:0007162 GO:0007165 GO:0007166 GO:0007167 GO:0007178 GO:0007179 GO:0007275 GO:0007389 GO:0007507 GO:0008015 GO:0008150 GO:0008152 GO:0008217 GO:0008283 GO:0008284 GO:0008285 GO:0008593 GO:0009628 GO:0009653 GO:0009719 GO:0009790 GO:0009792 GO:0009889 GO:0009890 GO:0009891 GO:0009892 GO:0009893 GO:0009953 GO:0009966 GO:0009967 GO:0009986 GO:0009987 GO:0010468 GO:0010556 GO:0010557 GO:0010558 GO:0010594 GO:0010596 GO:0010604 GO:0010605 GO:0010629 GO:0010632 GO:0010633 GO:0010646 GO:0010647 GO:0010810 GO:0010812 GO:0016020 GO:0016301 GO:0016310 GO:0016361 GO:0016477 GO:0016740 GO:0016772 GO:0016773 GO:0017002 GO:0017076 GO:0019199 GO:0019219 GO:0019222 GO:0019538 GO:0019838 GO:0019899 GO:0019900 GO:0019901 GO:0019955 GO:0021700 GO:0022603 GO:0023051 GO:0023056 GO:0030154 GO:0030155 GO:0030308 GO:0030334 GO:0030336 GO:0030425 GO:0030509 GO:0030510 GO:0030513 GO:0030554 GO:0030855 GO:0030856 GO:0030857 GO:0030858 GO:0031323 GO:0031324 GO:0031325 GO:0031326 GO:0031327 GO:0031328 GO:0032330 GO:0032332 GO:0032501 GO:0032502 GO:0032553 GO:0032555 GO:0032559 GO:0032924 GO:0032991 GO:0035239 GO:0035313 GO:0035639 GO:0035909 GO:0035912 GO:0036094 GO:0036211 GO:0036293 GO:0038023 GO:0040008 GO:0040012 GO:0040013 GO:0042127 GO:0042995 GO:0043005 GO:0043009 GO:0043025 GO:0043167 GO:0043168 GO:0043169 GO:0043170 GO:0043235 GO:0043412 GO:0043535 GO:0043537 GO:0044087 GO:0044089 GO:0044237 GO:0044238 GO:0044297 GO:0044319 GO:0044877 GO:0045446 GO:0045595 GO:0045596 GO:0045597 GO:0045601 GO:0045602 GO:0045603 GO:0045747 GO:0045765 GO:0045766 GO:0045893 GO:0045926 GO:0045935 GO:0045944 GO:0046332 GO:0046872 GO:0048185 GO:0048513 GO:0048514 GO:0048518 GO:0048519 GO:0048522 GO:0048523 GO:0048583 GO:0048584 GO:0048646 GO:0048729 GO:0048731 GO:0048762 GO:0048771 GO:0048844 GO:0048856 GO:0048869 GO:0048870 GO:0050431 GO:0050673 GO:0050678 GO:0050679 GO:0050680 GO:0050789 GO:0050793 GO:0050794 GO:0050896 GO:0051052 GO:0051093 GO:0051094 GO:0051128 GO:0051129 GO:0051130 GO:0051171 GO:0051173 GO:0051239 GO:0051240 GO:0051241 GO:0051252 GO:0051254 GO:0051893 GO:0051895 GO:0060089 GO:0060255 GO:0060317 GO:0060390 GO:0060391 GO:0060562 GO:0060836 GO:0060840 GO:0060841 GO:0061035 GO:0061036 GO:0061154 GO:0061298 GO:0065007 GO:0065008 GO:0070482 GO:0070724 GO:0070848 GO:0071363 GO:0071495 GO:0071559 GO:0071560 GO:0071695 GO:0071704 GO:0071772 GO:0071773 GO:0072132 GO:0080090 GO:0090092 GO:0090100 GO:0090109 GO:0090287 GO:0090500 GO:0097159 GO:0097367 GO:0098796 GO:0098797 GO:0098802 GO:0098821 GO:0110165 GO:0120025 GO:0140096 GO:0141091 GO:0150116 GO:0150118 GO:1901265 GO:1901342 GO:1901363 GO:1901564 GO:1901888 GO:1901889 GO:1901890 GO:1902531 GO:1902533 GO:1902680 GO:1903348 GO:1904018 GO:2000026 GO:2000145 GO:2000146 GO:2000810 GO:2001141
97	acylphosphatase 1	ACYP1	Homo sapiens (human)	9606			acylphosphatase activity biological_process catalytic activity cellular metabolic process cellular process hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity, acting on acid anhydrides hydrolase activity metabolic process molecular_function phosphate-containing compound metabolic process phosphorus metabolic process pyrophosphatase activity	GO:0003674 GO:0003824 GO:0003998 GO:0006793 GO:0006796 GO:0008150 GO:0008152 GO:0009987 GO:0016462 GO:0016787 GO:0016817 GO:0016818 GO:0044237
98	acylphosphatase 2	ACYP2	Homo sapiens (human)	9606	IgA glomerulonephritis bone osteosarcoma breast cancer bronchus cancer bronchus carcinoma cancer central nervous system cancer cerebral infarction cerebrovascular disease chromophobe renal cell carcinoma clear cell renal cell carcinoma collecting duct carcinoma colorectal cancer colorectal carcinoma embryoma gastrointestinal system cancer gliosarcoma hepatocellular carcinoma high grade glioma kidney cancer large intestine cancer laryngeal squamous cell carcinoma liver cancer lung benign neoplasm lung cancer lung carcinoma microphthalmia mixed glioma obsolete Matthew-Wood syndrome osteomyelitis osteosarcoma papillary renal cell carcinoma renal carcinoma renal cell carcinoma sarcomatoid renal cell carcinoma stomach cancer stomach carcinoma	DOID:0050819 DOID:0080199 DOID:1019 DOID:10534 DOID:10629 DOID:1324 DOID:1325 DOID:1612 DOID:162 DOID:263 DOID:2876 DOID:2986 DOID:3070 DOID:3071 DOID:3119 DOID:3347 DOID:3376 DOID:3526 DOID:3571 DOID:3620 DOID:3683 DOID:3904 DOID:3905 DOID:4450 DOID:4451 DOID:4464 DOID:4465 DOID:4467 DOID:4471 DOID:4473 DOID:4766 DOID:5076 DOID:5517 DOID:5672 DOID:6713 DOID:684 DOID:9256	acylphosphatase activity binding biological_process catalytic activity cellular anatomical entity cellular metabolic process cellular process cellular_component hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity, acting on acid anhydrides hydrolase activity identical protein binding intracellular membrane-bounded organelle intracellular organelle membrane-bounded organelle metabolic process mitochondrion molecular_function organelle phosphate-containing compound metabolic process phosphorus metabolic process protein binding pyrophosphatase activity	GO:0003674 GO:0003824 GO:0003998 GO:0005488 GO:0005515 GO:0005575 GO:0005739 GO:0006793 GO:0006796 GO:0008150 GO:0008152 GO:0009987 GO:0016462 GO:0016787 GO:0016817 GO:0016818 GO:0042802 GO:0043226 GO:0043227 GO:0043229 GO:0043231 GO:0044237 GO:0110165
101	ADAM metallopeptidase domain 8	ADAM8	Homo sapiens (human)	9606			alpha9-beta1 integrin-ADAM8 complex anatomical structure formation involved in morphogenesis anatomical structure morphogenesis angiogenesis binding biological regulation biological_process bounding membrane of organelle calcium ion binding canonical NF-kappaB signal transduction catalytic activity, acting on a protein catalytic activity cation binding cell adhesion molecule binding cell adhesion cell chemotaxis cell migration cell morphogenesis cell motility cell surface cell-cell adhesion cellular anatomical entity cellular component disassembly cellular component organization or biogenesis cellular component organization cellular process cellular response to chemical stimulus cellular response to decreased oxygen levels cellular response to hypoxia cellular response to oxygen levels cellular response to stimulus cellular response to stress cellular_component chemotaxis cytokine receptor binding cytoplasm cytoplasmic vesicle membrane cytoplasmic vesicle defense response dense core granule membrane developmental process endocytic vesicle endopeptidase activity establishment of localization export from cell external encapsulating structure organization extracellular matrix disassembly extracellular matrix organization extracellular structure organization ficolin-1-rich granule membrane hydrolase activity immune system process immunoglobulin receptor binding inflammatory response intracellular membrane-bounded organelle intracellular non-membrane-bounded organelle intracellular organelle intracellular signal transduction intracellular vesicle ion binding leukocyte chemotaxis leukocyte migration involved in inflammatory response leukocyte migration localization locomotion lymphocyte chemotaxis lymphocyte migration lysosome lytic vacuole macromolecule metabolic process membrane protein complex membrane-bounded organelle membrane metabolic process metal ion binding metalloendopeptidase activity metallopeptidase activity molecular_function mononuclear cell migration negative regulation of apoptotic process negative regulation of biological process negative regulation of cellular process negative regulation of neuron apoptotic process negative regulation of programmed cell death nitrogen compound metabolic process non-membrane-bounded organelle organelle membrane organelle organic substance metabolic process organonitrogen compound metabolic process peptidase activity phagocytic vesicle phagolysosome plasma membrane protein complex plasma membrane podosome positive regulation of MAPK cascade positive regulation of T cell activation positive regulation of T cell apoptotic process positive regulation of T cell differentiation in thymus positive regulation of T cell differentiation positive regulation of T cell migration positive regulation of acute inflammatory response positive regulation of apoptotic process positive regulation of biological process positive regulation of biosynthetic process positive regulation of bone resorption positive regulation of catabolic process positive regulation of cell activation positive regulation of cell adhesion positive regulation of cell communication positive regulation of cell development positive regulation of cell differentiation positive regulation of cell migration positive regulation of cell motility positive regulation of cell-cell adhesion positive regulation of cellular biosynthetic process positive regulation of cellular catabolic process positive regulation of cellular extravasation positive regulation of cellular metabolic process positive regulation of cellular process positive regulation of cytokine production positive regulation of defense response positive regulation of developmental process positive regulation of eosinophil migration positive regulation of epithelial to mesenchymal transition positive regulation of establishment of protein localization positive regulation of fibronectin-dependent thymocyte migration positive regulation of gene expression positive regulation of hemopoiesis positive regulation of immune response positive regulation of immune system process positive regulation of inflammatory response positive regulation of innate immune response positive regulation of intracellular signal transduction positive regulation of leukocyte activation positive regulation of leukocyte apoptotic process positive regulation of leukocyte cell-cell adhesion positive regulation of leukocyte differentiation positive regulation of leukocyte migration positive regulation of locomotion positive regulation of lymphocyte activation positive regulation of lymphocyte apoptotic process positive regulation of lymphocyte differentiation positive regulation of lymphocyte migration positive regulation of macromolecule biosynthetic process positive regulation of macromolecule metabolic process positive regulation of membrane protein ectodomain proteolysis positive regulation of metabolic process positive regulation of mononuclear cell migration positive regulation of multicellular organismal process positive regulation of neutrophil extravasation positive regulation of neutrophil migration positive regulation of nitrogen compound metabolic process positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of programmed cell death positive regulation of protein catabolic process positive regulation of protein localization positive regulation of protein maturation positive regulation of protein metabolic process positive regulation of protein processing positive regulation of protein secretion positive regulation of protein transport positive regulation of proteolysis positive regulation of response to biotic stimulus positive regulation of response to external stimulus positive regulation of response to stimulus positive regulation of secretion by cell positive regulation of secretion positive regulation of signal transduction positive regulation of signaling positive regulation of thymocyte apoptotic process positive regulation of thymocyte migration positive regulation of transport positive regulation of tumor necrosis factor (ligand) superfamily member 11 production positive regulation of tumor necrosis factor superfamily cytokine production primary metabolic process protein binding protein metabolic process protein-containing complex proteolysis regulation of MAPK cascade regulation of T cell activation regulation of T cell apoptotic process regulation of T cell differentiation in thymus regulation of T cell differentiation regulation of T cell migration regulation of acute inflammatory response regulation of apoptotic process regulation of biological process regulation of biosynthetic process regulation of bone remodeling regulation of bone resorption regulation of catabolic process regulation of cell activation regulation of cell adhesion regulation of cell communication regulation of cell development regulation of cell differentiation regulation of cell migration regulation of cell motility regulation of cell-cell adhesion regulation of cellular biosynthetic process regulation of cellular catabolic process regulation of cellular extravasation regulation of cellular localization regulation of cellular metabolic process regulation of cellular process regulation of cytokine production regulation of defense response regulation of developmental process regulation of eosinophil migration regulation of epithelial to mesenchymal transition regulation of establishment of protein localization regulation of fibronectin-dependent thymocyte migration regulation of gene expression regulation of hemopoiesis regulation of immune response regulation of immune system process regulation of inflammatory response regulation of innate immune response regulation of intracellular signal transduction regulation of leukocyte activation regulation of leukocyte apoptotic process regulation of leukocyte cell-cell adhesion regulation of leukocyte differentiation regulation of leukocyte migration regulation of localization regulation of locomotion regulation of lymphocyte activation regulation of lymphocyte apoptotic process regulation of lymphocyte differentiation regulation of lymphocyte migration regulation of macromolecule biosynthetic process regulation of macromolecule metabolic process regulation of membrane protein ectodomain proteolysis regulation of metabolic process regulation of mononuclear cell migration regulation of multicellular organismal development regulation of multicellular organismal process regulation of neuron apoptotic process regulation of neutrophil extravasation regulation of neutrophil migration regulation of nitrogen compound metabolic process regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction regulation of primary metabolic process regulation of programmed cell death regulation of protein catabolic process regulation of protein localization regulation of protein maturation regulation of protein metabolic process regulation of protein processing regulation of protein secretion regulation of protein transport regulation of proteolysis regulation of response to biotic stimulus regulation of response to external stimulus regulation of response to stimulus regulation of response to stress regulation of secretion by cell regulation of secretion regulation of signal transduction regulation of signaling regulation of thymocyte apoptotic process regulation of thymocyte migration regulation of tissue remodeling regulation of transport regulation of tumor necrosis factor (ligand) superfamily member 11 production regulation of tumor necrosis factor superfamily cytokine production response to abiotic stimulus response to chemical response to decreased oxygen levels response to hypoxia response to oxygen levels response to stimulus response to stress secondary lysosome secretion by cell secretion secretory granule membrane secretory granule secretory vesicle serine hydrolase activity serine-type endopeptidase activity serine-type peptidase activity signal release signal transduction signaling receptor binding specific granule membrane specific granule taxis tertiary granule membrane tertiary granule transition metal ion binding transport tumor necrosis factor receptor superfamily binding vacuole vesicle membrane vesicle zinc ion binding	GO:0000323 GO:0000902 GO:0001525 GO:0001666 GO:0001817 GO:0001819 GO:0002102 GO:0002376 GO:0002523 GO:0002673 GO:0002675 GO:0002682 GO:0002684 GO:0002685 GO:0002687 GO:0002691 GO:0002693 GO:0002694 GO:0002696 GO:0002831 GO:0002833 GO:0003674 GO:0003824 GO:0004175 GO:0004222 GO:0004252 GO:0005102 GO:0005126 GO:0005488 GO:0005509 GO:0005515 GO:0005575 GO:0005737 GO:0005764 GO:0005767 GO:0005773 GO:0005886 GO:0006508 GO:0006807 GO:0006810 GO:0006935 GO:0006950 GO:0006952 GO:0006954 GO:0007155 GO:0007165 GO:0007249 GO:0008150 GO:0008152 GO:0008233 GO:0008236 GO:0008237 GO:0008270 GO:0009628 GO:0009653 GO:0009889 GO:0009891 GO:0009893 GO:0009894 GO:0009896 GO:0009966 GO:0009967 GO:0009986 GO:0009987 GO:0010468 GO:0010556 GO:0010557 GO:0010604 GO:0010628 GO:0010646 GO:0010647 GO:0010717 GO:0010718 GO:0010720 GO:0010954 GO:0012506 GO:0016020 GO:0016043 GO:0016477 GO:0016787 GO:0017171 GO:0019222 GO:0019538 GO:0022407 GO:0022409 GO:0022411 GO:0022617 GO:0023051 GO:0023056 GO:0023061 GO:0030139 GO:0030141 GO:0030155 GO:0030162 GO:0030198 GO:0030334 GO:0030335 GO:0030595 GO:0030659 GO:0030667 GO:0031090 GO:0031323 GO:0031325 GO:0031326 GO:0031328 GO:0031329 GO:0031331 GO:0031347 GO:0031349 GO:0031410 GO:0031982 GO:0032010 GO:0032101 GO:0032103 GO:0032127 GO:0032502 GO:0032813 GO:0032879 GO:0032880 GO:0032940 GO:0032991 GO:0033081 GO:0033089 GO:0033554 GO:0034103 GO:0034987 GO:0035556 GO:0035579 GO:0036293 GO:0036294 GO:0040011 GO:0040012 GO:0040017 GO:0042176 GO:0042221 GO:0042330 GO:0042581 GO:0042981 GO:0043062 GO:0043065 GO:0043066 GO:0043067 GO:0043068 GO:0043069 GO:0043167 GO:0043169 GO:0043170 GO:0043226 GO:0043227 GO:0043228 GO:0043229 GO:0043231 GO:0043232 GO:0043408 GO:0043410 GO:0043523 GO:0043524 GO:0044238 GO:0045088 GO:0045089 GO:0045124 GO:0045229 GO:0045335 GO:0045580 GO:0045582 GO:0045595 GO:0045597 GO:0045619 GO:0045621 GO:0045732 GO:0045780 GO:0045785 GO:0045862 GO:0046850 GO:0046872 GO:0046903 GO:0046914 GO:0048247 GO:0048518 GO:0048519 GO:0048522 GO:0048523 GO:0048583 GO:0048584 GO:0048646 GO:0048870 GO:0050708 GO:0050714 GO:0050727 GO:0050729 GO:0050776 GO:0050778 GO:0050789 GO:0050793 GO:0050794 GO:0050839 GO:0050863 GO:0050865 GO:0050867 GO:0050870 GO:0050896 GO:0050900 GO:0051043 GO:0051044 GO:0051046 GO:0051047 GO:0051049 GO:0051050 GO:0051094 GO:0051171 GO:0051173 GO:0051179 GO:0051222 GO:0051223 GO:0051234 GO:0051239 GO:0051240 GO:0051246 GO:0051247 GO:0051249 GO:0051251 GO:0051716 GO:0051896 GO:0051897 GO:0060255 GO:0060284 GO:0060326 GO:0060341 GO:0065007 GO:0070201 GO:0070228 GO:0070230 GO:0070232 GO:0070234 GO:0070243 GO:0070245 GO:0070482 GO:0070613 GO:0070820 GO:0070821 GO:0070887 GO:0071133 GO:0071453 GO:0071456 GO:0071674 GO:0071675 GO:0071677 GO:0071704 GO:0071840 GO:0072676 GO:0080090 GO:0080134 GO:0097708 GO:0098588 GO:0098609 GO:0098796 GO:0098797 GO:0099503 GO:0101003 GO:0110165 GO:0140096 GO:0140352 GO:1901564 GO:1902105 GO:1902107 GO:1902531 GO:1902533 GO:1902622 GO:1902624 GO:1903037 GO:1903039 GO:1903317 GO:1903319 GO:1903530 GO:1903532 GO:1903555 GO:1903557 GO:1903706 GO:1903708 GO:1903829 GO:1904951 GO:2000026 GO:2000106 GO:2000108 GO:2000145 GO:2000147 GO:2000307 GO:2000309 GO:2000389 GO:2000391 GO:2000401 GO:2000403 GO:2000404 GO:2000406 GO:2000410 GO:2000412 GO:2000413 GO:2000415 GO:2000416 GO:2000418
102	ADAM metallopeptidase domain 10	ADAM10	Homo sapiens (human)	9606			Golgi apparatus Golgi membrane Golgi-associated vesicle Notch signaling pathway SH3 domain binding adherens junction organization adherens junction amide metabolic process amyloid precursor protein catabolic process amyloid precursor protein metabolic process anatomical structure development anchoring junction axon binding biological regulation biological_process bounding membrane of organelle catabolic process catalytic activity, acting on a protein catalytic activity cation binding cell activation cell adhesion molecule binding cell communication cell junction organization cell junction cell projection cell surface receptor signaling pathway cell surface cell-cell junction organization cell-cell junction cell-cell signaling cell-substrate junction cellular anatomical entity cellular component assembly cellular component disassembly cellular component organization or biogenesis cellular component organization cellular metabolic process cellular process cellular_component chordate embryonic development clathrin-coated vesicle coated vesicle cochlea development constitutive protein ectodomain proteolysis cytoplasm cytoplasmic vesicle membrane cytoplasmic vesicle dendrite developmental process dipeptidase activity embryo development ending in birth or egg hatching embryo development endopeptidase activity endoplasmic reticulum lumen enzyme binding epidermal growth factor receptor ligand maturation exopeptidase activity external encapsulating structure organization extracellular exosome extracellular matrix disassembly extracellular matrix organization extracellular membrane-bounded organelle extracellular organelle extracellular structure organization extracellular vesicle focal adhesion glutamatergic synapse hormone metabolic process hydrolase activity identical protein binding immune system process in utero embryonic development integrin binding integrin-mediated signaling pathway intracellular membrane-bounded organelle intracellular organelle lumen intracellular organelle intracellular vesicle ion binding kinase binding leukocyte activation macromolecule catabolic process macromolecule metabolic process macromolecule modification membrane protein complex membrane protein ectodomain proteolysis membrane protein proteolysis membrane-bounded organelle membrane-enclosed lumen membrane metabolic process metal ion binding metallodipeptidase activity metalloendopeptidase activity involved in amyloid precursor protein catabolic process metalloendopeptidase activity metalloexopeptidase activity metallopeptidase activity molecular adaptor activity molecular_function monocyte activation multicellular organism development multicellular organismal process myeloid leukocyte activation negative regulation of biological process negative regulation of biosynthetic process negative regulation of cell adhesion negative regulation of cellular biosynthetic process negative regulation of cellular metabolic process negative regulation of cellular process negative regulation of gene expression negative regulation of macromolecule biosynthetic process negative regulation of macromolecule metabolic process negative regulation of metabolic process neuron projection nitrogen compound metabolic process nucleus organelle lumen organelle membrane organelle organic substance catabolic process organic substance metabolic process organonitrogen compound catabolic process organonitrogen compound metabolic process peptidase activity peptide hormone processing peptide metabolic process perinuclear endoplasmic reticulum phosphate-containing compound metabolic process phosphorus metabolic process phosphorylation plasma membrane bounded cell projection plasma membrane region plasma membrane pore complex assembly pore complex positive regulation of T cell chemotaxis positive regulation of T cell migration positive regulation of biological process positive regulation of cell growth positive regulation of cell migration positive regulation of cell motility positive regulation of cell population proliferation positive regulation of cellular process positive regulation of chemotaxis positive regulation of growth positive regulation of immune system process positive regulation of leukocyte chemotaxis positive regulation of leukocyte migration positive regulation of locomotion positive regulation of lymphocyte chemotaxis positive regulation of lymphocyte migration positive regulation of mononuclear cell migration positive regulation of response to external stimulus positive regulation of response to stimulus postsynapse organization postsynaptic density postsynaptic specialization primary metabolic process protein binding protein catabolic process at postsynapse protein catabolic process at synapse protein catabolic process protein dimerization activity protein domain specific binding protein homodimerization activity protein kinase binding protein maturation protein metabolic process protein modification process protein phosphorylation protein processing protein-containing complex assembly protein-containing complex binding protein-containing complex organization protein-containing complex proteolysis regulation of Notch signaling pathway regulation of T cell chemotaxis regulation of T cell migration regulation of biological process regulation of biological quality regulation of biosynthetic process regulation of cell adhesion regulation of cell communication regulation of cell growth regulation of cell migration regulation of cell motility regulation of cell population proliferation regulation of cellular biosynthetic process regulation of cellular component organization regulation of cellular localization regulation of cellular metabolic process regulation of cellular process regulation of chemotaxis regulation of developmental process regulation of gene expression regulation of growth regulation of hormone levels regulation of immune system process regulation of leukocyte chemotaxis regulation of leukocyte migration regulation of localization regulation of locomotion regulation of lymphocyte chemotaxis regulation of lymphocyte migration regulation of macromolecule biosynthetic process regulation of macromolecule metabolic process regulation of metabolic process regulation of mononuclear cell migration regulation of multicellular organismal development regulation of multicellular organismal process regulation of neurotransmitter receptor localization to postsynaptic specialization membrane regulation of postsynapse organization regulation of protein localization to cell periphery regulation of protein localization to membrane regulation of protein localization to synapse regulation of protein localization regulation of receptor localization to synapse regulation of response to external stimulus regulation of response to stimulus regulation of signal transduction regulation of signaling regulation of synapse organization regulation of vasculature development response to chemical response to cytokine response to organic substance response to stimulus response to tumor necrosis factor secretory granule membrane signal transduction signaling receptor binding signaling receptor ligand precursor processing signaling specific granule membrane synapse synaptic membrane tertiary granule membrane tetraspanin-enriched microdomain vesicle membrane vesicle	GO:0000139 GO:0001558 GO:0001701 GO:0001775 GO:0002274 GO:0002376 GO:0002682 GO:0002684 GO:0002685 GO:0002687 GO:0002688 GO:0002690 GO:0003674 GO:0003824 GO:0004175 GO:0004222 GO:0005102 GO:0005178 GO:0005488 GO:0005515 GO:0005575 GO:0005634 GO:0005737 GO:0005788 GO:0005794 GO:0005798 GO:0005886 GO:0005911 GO:0005912 GO:0005925 GO:0006468 GO:0006508 GO:0006509 GO:0006518 GO:0006793 GO:0006796 GO:0006807 GO:0007154 GO:0007162 GO:0007165 GO:0007166 GO:0007219 GO:0007229 GO:0007267 GO:0007275 GO:0008150 GO:0008152 GO:0008233 GO:0008235 GO:0008237 GO:0008238 GO:0008284 GO:0008593 GO:0009056 GO:0009057 GO:0009790 GO:0009792 GO:0009889 GO:0009890 GO:0009892 GO:0009966 GO:0009986 GO:0009987 GO:0010033 GO:0010468 GO:0010556 GO:0010558 GO:0010605 GO:0010629 GO:0010646 GO:0010817 GO:0010819 GO:0010820 GO:0012506 GO:0014069 GO:0016020 GO:0016043 GO:0016310 GO:0016485 GO:0016486 GO:0016787 GO:0016805 GO:0017124 GO:0019222 GO:0019538 GO:0019899 GO:0019900 GO:0019901 GO:0019904 GO:0022411 GO:0022607 GO:0022617 GO:0023051 GO:0023052 GO:0030054 GO:0030055 GO:0030135 GO:0030136 GO:0030155 GO:0030163 GO:0030198 GO:0030307 GO:0030334 GO:0030335 GO:0030424 GO:0030425 GO:0030659 GO:0030667 GO:0031090 GO:0031323 GO:0031324 GO:0031326 GO:0031327 GO:0031410 GO:0031974 GO:0031982 GO:0032101 GO:0032103 GO:0032501 GO:0032502 GO:0032879 GO:0032880 GO:0032991 GO:0033619 GO:0034097 GO:0034330 GO:0034332 GO:0034612 GO:0035579 GO:0036211 GO:0038004 GO:0040008 GO:0040012 GO:0040017 GO:0042117 GO:0042127 GO:0042221 GO:0042445 GO:0042802 GO:0042803 GO:0042982 GO:0042987 GO:0042995 GO:0043005 GO:0043009 GO:0043062 GO:0043167 GO:0043169 GO:0043170 GO:0043226 GO:0043227 GO:0043229 GO:0043230 GO:0043231 GO:0043233 GO:0043412 GO:0043603 GO:0043933 GO:0044237 GO:0044238 GO:0044877 GO:0045202 GO:0045216 GO:0045229 GO:0045321 GO:0045927 GO:0046872 GO:0046930 GO:0046931 GO:0046983 GO:0048518 GO:0048519 GO:0048522 GO:0048523 GO:0048583 GO:0048584 GO:0048856 GO:0050789 GO:0050793 GO:0050794 GO:0050807 GO:0050839 GO:0050896 GO:0050920 GO:0050921 GO:0051089 GO:0051128 GO:0051239 GO:0051604 GO:0060090 GO:0060255 GO:0060341 GO:0065003 GO:0065007 GO:0065008 GO:0065010 GO:0070013 GO:0070062 GO:0070161 GO:0070573 GO:0070821 GO:0071675 GO:0071677 GO:0071704 GO:0071840 GO:0090102 GO:0097038 GO:0097060 GO:0097197 GO:0097708 GO:0098588 GO:0098590 GO:0098696 GO:0098796 GO:0098978 GO:0099173 GO:0099175 GO:0099572 GO:0110165 GO:0120025 GO:0140096 GO:0140131 GO:0140246 GO:0140249 GO:0140448 GO:1901342 GO:1901564 GO:1901565 GO:1901575 GO:1901623 GO:1902473 GO:1902683 GO:1902945 GO:1903561 GO:1904375 GO:1905475 GO:2000026 GO:2000145 GO:2000147 GO:2000401 GO:2000403 GO:2000404 GO:2000406
103	adenosine deaminase RNA specific	ADAR Aliases: ADAR1 DRADA Double-stranded RNA-specific adenosine deaminase	Homo sapiens (human)	9606			DNA binding RISC complex assembly RNA binding RNA metabolic process RNA modification RNA processing adenosine deaminase activity adenosine to inosine editing anatomical structure development apoptotic process base conversion or substitution editing binding biological process involved in interspecies interaction between organisms biological regulation biological_process catalytic activity cation binding cell death cell development cell differentiation cellular anatomical entity cellular aromatic compound metabolic process cellular component assembly cellular component organization or biogenesis cellular component organization cellular developmental process cellular localization cellular macromolecule localization cellular metabolic process cellular nitrogen compound metabolic process cellular process cellular response to virus cellular_component cytoplasm cytosol deaminase activity defense response to other organism defense response to symbiont defense response to virus defense response definitive hemopoiesis developmental process double-stranded RNA adenosine deaminase activity double-stranded RNA binding epithelial cell apoptotic process erythrocyte differentiation establishment of localization in cell establishment of localization establishment of protein localization to organelle establishment of protein localization hematopoietic progenitor cell differentiation hematopoietic stem cell homeostasis hemopoiesis hepatocyte apoptotic process heterocycle metabolic process homeostasis of number of cells homeostatic process hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds hydrolase activity immune response immune system process import into nucleus innate immune response intracellular membrane-bounded organelle intracellular non-membrane-bounded organelle intracellular organelle intracellular protein transport intracellular transport ion binding localization mRNA metabolic process mRNA processing macromolecule localization macromolecule metabolic process macromolecule modification membrane-bounded organelle membrane metabolic process metal ion binding miRNA processing mitochondrion molecular_function multicellular organismal process multicellular organismal-level homeostasis myeloid cell differentiation ncRNA metabolic process ncRNA processing negative regulation of apoptotic process negative regulation of biological process negative regulation of catalytic activity negative regulation of cell communication negative regulation of cellular metabolic process negative regulation of cellular process negative regulation of cytokine-mediated signaling pathway negative regulation of defense response negative regulation of epithelial cell apoptotic process negative regulation of gene silencing by regulatory ncRNA negative regulation of hepatocyte apoptotic process negative regulation of immune response negative regulation of immune system process negative regulation of innate immune response negative regulation of kinase activity negative regulation of macromolecule metabolic process negative regulation of metabolic process negative regulation of molecular function negative regulation of nitrogen compound metabolic process negative regulation of phosphate metabolic process negative regulation of phosphorus metabolic process negative regulation of phosphorylation negative regulation of post-transcriptional gene silencing by regulatory ncRNA negative regulation of post-transcriptional gene silencing negative regulation of programmed cell death negative regulation of protein kinase activity by regulation of protein phosphorylation negative regulation of protein kinase activity negative regulation of protein metabolic process negative regulation of protein modification process negative regulation of protein phosphorylation negative regulation of response to biotic stimulus negative regulation of response to cytokine stimulus negative regulation of response to external stimulus negative regulation of response to stimulus negative regulation of signal transduction negative regulation of signaling negative regulation of transferase activity negative regulation of type I interferon-mediated signaling pathway nitrogen compound metabolic process nitrogen compound transport non-membrane-bounded organelle nuclear export nuclear protein-containing complex nuclear transport nucleic acid binding nucleic acid metabolic process nucleobase-containing compound metabolic process nucleocytoplasmic transport nucleolus nucleoplasm nucleus organelle organic cyclic compound binding organic cyclic compound metabolic process organic substance metabolic process organic substance transport osteoblast differentiation positive regulation of biological process positive regulation of biosynthetic process positive regulation of cellular biosynthetic process positive regulation of cellular metabolic process positive regulation of cellular process positive regulation of gene expression positive regulation of macromolecule biosynthetic process positive regulation of macromolecule metabolic process positive regulation of metabolic process positive regulation of viral genome replication positive regulation of viral process pre-miRNA processing primary metabolic process programmed cell death protein binding protein export from nucleus protein import into nucleus protein localization to nucleus protein localization to organelle protein localization protein transport protein-RNA complex assembly protein-RNA complex organization protein-containing complex assembly protein-containing complex organization protein-containing complex regulation of apoptotic process regulation of biological process regulation of biosynthetic process regulation of catalytic activity regulation of cell communication regulation of cellular biosynthetic process regulation of cellular metabolic process regulation of cellular process regulation of cytokine-mediated signaling pathway regulation of defense response regulation of epithelial cell apoptotic process regulation of gene expression regulation of gene silencing by regulatory ncRNA regulation of hepatocyte apoptotic process regulation of immune response regulation of immune system process regulation of innate immune response regulation of kinase activity regulation of macromolecule biosynthetic process regulation of macromolecule metabolic process regulation of metabolic process regulation of molecular function regulation of nitrogen compound metabolic process regulation of phosphate metabolic process regulation of phosphorus metabolic process regulation of phosphorylation regulation of post-transcriptional gene silencing by regulatory ncRNA regulation of post-transcriptional gene silencing regulation of primary metabolic process regulation of programmed cell death regulation of protein kinase activity regulation of protein metabolic process regulation of protein modification process regulation of protein phosphorylation regulation of response to biotic stimulus regulation of response to cytokine stimulus regulation of response to external stimulus regulation of response to stimulus regulation of response to stress regulation of signal transduction regulation of signaling regulation of transferase activity regulation of type I interferon-mediated signaling pathway regulation of viral genome replication regulation of viral life cycle regulation of viral process regulatory ncRNA processing response to biotic stimulus response to chemical response to cytokine response to external biotic stimulus response to external stimulus response to interferon-alpha response to organic substance response to other organism response to stimulus response to stress response to virus ribonucleoprotein complex somatic diversification of immune receptors via somatic mutation somatic diversification of immune receptors spliceosomal complex supraspliceosomal complex tRNA-specific adenosine deaminase activity transport	GO:0001649 GO:0001932 GO:0001933 GO:0001959 GO:0001960 GO:0002200 GO:0002244 GO:0002376 GO:0002566 GO:0002682 GO:0002683 GO:0002831 GO:0002832 GO:0003674 GO:0003676 GO:0003677 GO:0003723 GO:0003725 GO:0003726 GO:0003824 GO:0004000 GO:0005488 GO:0005515 GO:0005575 GO:0005634 GO:0005654 GO:0005681 GO:0005730 GO:0005737 GO:0005739 GO:0005829 GO:0006139 GO:0006382 GO:0006396 GO:0006397 GO:0006469 GO:0006606 GO:0006611 GO:0006725 GO:0006807 GO:0006810 GO:0006886 GO:0006913 GO:0006915 GO:0006950 GO:0006952 GO:0006955 GO:0008104 GO:0008150 GO:0008152 GO:0008219 GO:0008251 GO:0009451 GO:0009605 GO:0009607 GO:0009615 GO:0009889 GO:0009891 GO:0009892 GO:0009893 GO:0009966 GO:0009968 GO:0009987 GO:0010033 GO:0010468 GO:0010556 GO:0010557 GO:0010563 GO:0010604 GO:0010605 GO:0010628 GO:0010646 GO:0010648 GO:0012501 GO:0015031 GO:0016020 GO:0016043 GO:0016070 GO:0016071 GO:0016553 GO:0016787 GO:0016810 GO:0016814 GO:0019220 GO:0019222 GO:0019239 GO:0022607 GO:0022618 GO:0023051 GO:0023057 GO:0030097 GO:0030099 GO:0030154 GO:0030218 GO:0031054 GO:0031323 GO:0031324 GO:0031325 GO:0031326 GO:0031328 GO:0031347 GO:0031348 GO:0031399 GO:0031400 GO:0032101 GO:0032102 GO:0032501 GO:0032502 GO:0032991 GO:0033036 GO:0033365 GO:0033673 GO:0034097 GO:0034470 GO:0034504 GO:0034641 GO:0034660 GO:0035196 GO:0035455 GO:0042221 GO:0042325 GO:0042326 GO:0042592 GO:0042981 GO:0043066 GO:0043067 GO:0043069 GO:0043086 GO:0043167 GO:0043169 GO:0043170 GO:0043207 GO:0043226 GO:0043227 GO:0043228 GO:0043229 GO:0043231 GO:0043232 GO:0043412 GO:0043549 GO:0043933 GO:0044092 GO:0044237 GO:0044238 GO:0044387 GO:0044419 GO:0044530 GO:0045069 GO:0045070 GO:0045087 GO:0045088 GO:0045184 GO:0045824 GO:0045859 GO:0045936 GO:0046483 GO:0046872 GO:0046907 GO:0048468 GO:0048518 GO:0048519 GO:0048522 GO:0048523 GO:0048524 GO:0048583 GO:0048585 GO:0048856 GO:0048869 GO:0048871 GO:0048872 GO:0050776 GO:0050777 GO:0050789 GO:0050790 GO:0050792 GO:0050794 GO:0050896 GO:0051168 GO:0051169 GO:0051170 GO:0051171 GO:0051172 GO:0051174 GO:0051179 GO:0051234 GO:0051246 GO:0051248 GO:0051338 GO:0051348 GO:0051607 GO:0051641 GO:0051649 GO:0051707 GO:0060147 GO:0060149 GO:0060216 GO:0060255 GO:0060338 GO:0060339 GO:0060759 GO:0060761 GO:0060966 GO:0060967 GO:0061484 GO:0065003 GO:0065007 GO:0065009 GO:0070727 GO:0070918 GO:0070922 GO:0071702 GO:0071704 GO:0071705 GO:0071826 GO:0071840 GO:0072594 GO:0080090 GO:0080134 GO:0090304 GO:0097159 GO:0097284 GO:0098542 GO:0098586 GO:0110165 GO:0140513 GO:0140546 GO:1900368 GO:1900369 GO:1901360 GO:1903900 GO:1903943 GO:1903944 GO:1904019 GO:1904035 GO:1904036 GO:1990904
107	adenylate cyclase 1	ADCY1	Homo sapiens (human)	9606			ATP binding G protein-coupled receptor signaling pathway Schaffer collateral - CA1 synapse adenyl nucleotide binding adenyl ribonucleotide binding adenylate cyclase activity adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway anatomical structure morphogenesis anion binding aromatic compound biosynthetic process axonogenesis behavior binding biological regulation biological_process biosynthetic process cAMP biosynthetic process cAMP metabolic process cAMP-mediated signaling calcium- and calmodulin-responsive adenylate cyclase activity calmodulin binding carbohydrate derivative binding carbohydrate derivative biosynthetic process carbohydrate derivative metabolic process catalytic activity cation binding cell junction cell projection morphogenesis cell projection organization cellular anatomical entity morphogenesis cellular anatomical entity cellular aromatic compound metabolic process cellular biosynthetic process cellular component organization or biogenesis cellular component organization cellular metabolic process cellular nitrogen compound biosynthetic process cellular nitrogen compound metabolic process cellular process cellular response to alcohol cellular response to calcium ion cellular response to chemical stimulus cellular response to forskolin cellular response to inorganic substance cellular response to ketone cellular response to lipid cellular response to metal ion cellular response to organic cyclic compound cellular response to organic substance cellular response to oxygen-containing compound cellular response to salt cellular response to stimulus cellular_component circadian rhythm cognition cyclase activity cyclic nucleotide biosynthetic process cyclic nucleotide metabolic process cyclic purine nucleotide metabolic process cyclic-nucleotide-mediated signaling cytoplasm defense response developmental process extracellular exosome extracellular membrane-bounded organelle extracellular organelle extracellular vesicle glutamatergic synapse heterocycle biosynthetic process heterocycle metabolic process heterocyclic compound binding hippocampal mossy fiber to CA3 synapse inflammatory response intracellular signal transduction ion binding learning or memory long-term memory lyase activity membrane microdomain membrane raft membrane-bounded organelle membrane memory metabolic process metal ion binding modulation of chemical synaptic transmission molecular_function multicellular organismal process nervous system process neuroinflammatory response neuron projection morphogenesis neuron to neuron synapse nitrogen compound metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoside phosphate binding nucleoside phosphate biosynthetic process nucleoside phosphate metabolic process nucleotide binding nucleotide biosynthetic process nucleotide metabolic process organelle organic cyclic compound binding organic cyclic compound biosynthetic process organic cyclic compound metabolic process organic substance biosynthetic process organic substance metabolic process organonitrogen compound biosynthetic process organonitrogen compound metabolic process organophosphate biosynthetic process organophosphate metabolic process phosphate-containing compound metabolic process phosphorus metabolic process phosphorus-oxygen lyase activity plasma membrane bounded cell projection morphogenesis plasma membrane region plasma membrane positive regulation of CREB transcription factor activity positive regulation of DNA-binding transcription factor activity positive regulation of biological process positive regulation of cell communication positive regulation of cellular process positive regulation of long-term synaptic potentiation positive regulation of molecular function positive regulation of signaling positive regulation of synaptic transmission postsynaptic density membrane postsynaptic specialization membrane presynapse presynaptic modulation of chemical synaptic transmission primary metabolic process protein binding purine nucleotide binding purine nucleotide biosynthetic process purine nucleotide metabolic process purine ribonucleoside triphosphate binding purine ribonucleotide binding purine ribonucleotide biosynthetic process purine ribonucleotide metabolic process purine-containing compound biosynthetic process purine-containing compound metabolic process regulation of DNA-binding transcription factor activity regulation of DNA-templated transcription regulation of RNA biosynthetic process regulation of RNA metabolic process regulation of biological process regulation of biological quality regulation of biosynthetic process regulation of cell communication regulation of cellular biosynthetic process regulation of cellular metabolic process regulation of cellular process regulation of circadian rhythm regulation of gene expression regulation of long-term synaptic potentiation regulation of macromolecule biosynthetic process regulation of macromolecule metabolic process regulation of metabolic process regulation of molecular function regulation of nitrogen compound metabolic process regulation of nucleobase-containing compound metabolic process regulation of primary metabolic process regulation of signaling regulation of synaptic plasticity regulation of trans-synaptic signaling response to alcohol response to calcium ion response to chemical response to forskolin response to inorganic substance response to ketone response to lipid response to metal ion response to organic cyclic compound response to organic substance response to oxygen-containing compound response to salt response to stimulus response to stress response to xenobiotic stimulus rhythmic process ribonucleotide binding ribonucleotide biosynthetic process ribonucleotide metabolic process ribose phosphate biosynthetic process ribose phosphate metabolic process second-messenger-mediated signaling signal transduction small molecule binding small molecule metabolic process synapse synaptic membrane system process vesicle	GO:0000166 GO:0003008 GO:0003674 GO:0003824 GO:0004016 GO:0005488 GO:0005515 GO:0005516 GO:0005524 GO:0005575 GO:0005737 GO:0005886 GO:0006139 GO:0006163 GO:0006164 GO:0006171 GO:0006355 GO:0006725 GO:0006753 GO:0006793 GO:0006796 GO:0006807 GO:0006950 GO:0006952 GO:0006954 GO:0007165 GO:0007186 GO:0007188 GO:0007189 GO:0007409 GO:0007610 GO:0007611 GO:0007613 GO:0007616 GO:0007623 GO:0008150 GO:0008152 GO:0008294 GO:0009058 GO:0009117 GO:0009150 GO:0009152 GO:0009165 GO:0009187 GO:0009190 GO:0009259 GO:0009260 GO:0009410 GO:0009653 GO:0009889 GO:0009975 GO:0009987 GO:0010033 GO:0010035 GO:0010038 GO:0010468 GO:0010556 GO:0010646 GO:0010647 GO:0014070 GO:0016020 GO:0016043 GO:0016829 GO:0016849 GO:0017076 GO:0018130 GO:0019219 GO:0019222 GO:0019438 GO:0019637 GO:0019693 GO:0019932 GO:0019933 GO:0019935 GO:0023051 GO:0023056 GO:0030030 GO:0030054 GO:0030554 GO:0031323 GO:0031326 GO:0031982 GO:0032501 GO:0032502 GO:0032553 GO:0032555 GO:0032559 GO:0032793 GO:0032989 GO:0033993 GO:0034641 GO:0034654 GO:0035556 GO:0035639 GO:0036094 GO:0042221 GO:0042752 GO:0043167 GO:0043168 GO:0043169 GO:0043226 GO:0043227 GO:0043230 GO:0044093 GO:0044237 GO:0044238 GO:0044249 GO:0044271 GO:0044281 GO:0045121 GO:0045202 GO:0046058 GO:0046390 GO:0046483 GO:0046872 GO:0048167 GO:0048511 GO:0048518 GO:0048522 GO:0048812 GO:0048858 GO:0050789 GO:0050794 GO:0050804 GO:0050806 GO:0050877 GO:0050890 GO:0050896 GO:0051090 GO:0051091 GO:0051171 GO:0051252 GO:0051592 GO:0051716 GO:0052652 GO:0055086 GO:0060255 GO:0065007 GO:0065008 GO:0065009 GO:0065010 GO:0070062 GO:0070887 GO:0071241 GO:0071248 GO:0071277 GO:0071310 GO:0071396 GO:0071407 GO:0071704 GO:0071840 GO:0072521 GO:0072522 GO:0080090 GO:0090407 GO:0097060 GO:0097159 GO:0097305 GO:0097306 GO:0097367 GO:0098590 GO:0098685 GO:0098686 GO:0098793 GO:0098839 GO:0098857 GO:0098978 GO:0098984 GO:0099171 GO:0099177 GO:0099634 GO:0110165 GO:0120039 GO:0150076 GO:1900271 GO:1900273 GO:1901135 GO:1901137 GO:1901265 GO:1901293 GO:1901360 GO:1901362 GO:1901363 GO:1901564 GO:1901566 GO:1901576 GO:1901654 GO:1901655 GO:1901700 GO:1901701 GO:1902074 GO:1902075 GO:1903561 GO:1904321 GO:1904322 GO:2001141
108	adenylate cyclase 2	ADCY2	Homo sapiens (human)	9606			ATP binding G protein-coupled receptor signaling pathway adenyl nucleotide binding adenyl ribonucleotide binding adenylate cyclase activity adenylate cyclase binding adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway anion binding aromatic compound biosynthetic process binding biological regulation biological_process biosynthetic process cAMP biosynthetic process cAMP metabolic process cAMP-mediated signaling carbohydrate derivative binding carbohydrate derivative biosynthetic process carbohydrate derivative metabolic process catalytic activity cation binding cell projection cellular anatomical entity cellular aromatic compound metabolic process cellular biosynthetic process cellular metabolic process cellular nitrogen compound biosynthetic process cellular nitrogen compound metabolic process cellular process cellular response to alcohol cellular response to chemical stimulus cellular response to forskolin cellular response to ketone cellular response to lipid cellular response to organic cyclic compound cellular response to organic substance cellular response to oxygen-containing compound cellular response to stimulus cellular_component cyclase activity cyclic nucleotide biosynthetic process cyclic nucleotide metabolic process cyclic purine nucleotide metabolic process cyclic-nucleotide-mediated signaling cytoplasm dendrite enzyme binding heterocycle biosynthetic process heterocycle metabolic process heterocyclic compound binding intracellular signal transduction ion binding lyase activity magnesium ion binding manganese ion binding membrane microdomain membrane raft membrane metabolic process metal ion binding molecular_function neuron projection nitrogen compound metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoside phosphate binding nucleoside phosphate biosynthetic process nucleoside phosphate metabolic process nucleotide binding nucleotide biosynthetic process nucleotide metabolic process organic cyclic compound binding organic cyclic compound biosynthetic process organic cyclic compound metabolic process organic substance biosynthetic process organic substance metabolic process organonitrogen compound biosynthetic process organonitrogen compound metabolic process organophosphate biosynthetic process organophosphate metabolic process phosphate-containing compound metabolic process phosphorus metabolic process phosphorus-oxygen lyase activity plasma membrane bounded cell projection plasma membrane primary metabolic process protein binding purine nucleotide binding purine nucleotide biosynthetic process purine nucleotide metabolic process purine ribonucleoside triphosphate binding purine ribonucleotide binding purine ribonucleotide biosynthetic process purine ribonucleotide metabolic process purine-containing compound biosynthetic process purine-containing compound metabolic process regulation of biological process regulation of cellular process response to alcohol response to chemical response to forskolin response to ketone response to lipid response to organic cyclic compound response to organic substance response to oxygen-containing compound response to stimulus ribonucleotide binding ribonucleotide biosynthetic process ribonucleotide metabolic process ribose phosphate biosynthetic process ribose phosphate metabolic process second-messenger-mediated signaling signal transduction small molecule binding small molecule metabolic process transition metal ion binding	GO:0000166 GO:0000287 GO:0003674 GO:0003824 GO:0004016 GO:0005488 GO:0005515 GO:0005524 GO:0005575 GO:0005737 GO:0005886 GO:0006139 GO:0006163 GO:0006164 GO:0006171 GO:0006725 GO:0006753 GO:0006793 GO:0006796 GO:0006807 GO:0007165 GO:0007186 GO:0007188 GO:0007189 GO:0007193 GO:0008150 GO:0008152 GO:0008179 GO:0009058 GO:0009117 GO:0009150 GO:0009152 GO:0009165 GO:0009187 GO:0009190 GO:0009259 GO:0009260 GO:0009975 GO:0009987 GO:0010033 GO:0014070 GO:0016020 GO:0016829 GO:0016849 GO:0017076 GO:0018130 GO:0019438 GO:0019637 GO:0019693 GO:0019899 GO:0019932 GO:0019933 GO:0019935 GO:0030145 GO:0030425 GO:0030554 GO:0032553 GO:0032555 GO:0032559 GO:0033993 GO:0034641 GO:0034654 GO:0035556 GO:0035639 GO:0036094 GO:0042221 GO:0042995 GO:0043005 GO:0043167 GO:0043168 GO:0043169 GO:0044237 GO:0044238 GO:0044249 GO:0044271 GO:0044281 GO:0045121 GO:0046058 GO:0046390 GO:0046483 GO:0046872 GO:0046914 GO:0050789 GO:0050794 GO:0050896 GO:0051716 GO:0052652 GO:0055086 GO:0065007 GO:0070887 GO:0071310 GO:0071396 GO:0071407 GO:0071704 GO:0072521 GO:0072522 GO:0090407 GO:0097159 GO:0097305 GO:0097306 GO:0097367 GO:0098857 GO:0110165 GO:0120025 GO:1901135 GO:1901137 GO:1901265 GO:1901293 GO:1901360 GO:1901362 GO:1901363 GO:1901564 GO:1901566 GO:1901576 GO:1901654 GO:1901655 GO:1901700 GO:1901701 GO:1904321 GO:1904322
109	adenylate cyclase 3	ADCY3	Homo sapiens (human)	9606			ATP binding G protein-coupled receptor signaling pathway Golgi apparatus acrosome reaction adenyl nucleotide binding adenyl ribonucleotide binding adenylate cyclase activity adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway anion binding aromatic compound biosynthetic process associative learning behavior binding biological regulation biological_process biosynthetic process bounding membrane of organelle cAMP biosynthetic process cAMP metabolic process calmodulin binding carbohydrate derivative binding carbohydrate derivative biosynthetic process carbohydrate derivative metabolic process catalytic activity cation binding cell motility cell projection membrane cell projection cellular anatomical entity cellular aromatic compound metabolic process cellular biosynthetic process cellular metabolic process cellular nitrogen compound biosynthetic process cellular nitrogen compound metabolic process cellular process cellular response to alcohol cellular response to chemical stimulus cellular response to forskolin cellular response to ketone cellular response to lipid cellular response to organic cyclic compound cellular response to organic substance cellular response to oxygen-containing compound cellular response to stimulus cellular_component chemosensory behavior ciliary membrane cilium movement involved in cell motility cilium movement cilium or flagellum-dependent cell motility cilium-dependent cell motility cilium cognition cyclase activity cyclic nucleotide biosynthetic process cyclic nucleotide metabolic process cyclic purine nucleotide metabolic process cytoplasm fertilization flagellated sperm motility heterocycle biosynthetic process heterocycle metabolic process heterocyclic compound binding intracellular membrane-bounded organelle intracellular organelle intracellular signal transduction ion binding learning or memory learning lyase activity membrane-bounded organelle membrane metabolic process metal ion binding microtubule-based movement microtubule-based process molecular_function multicellular organismal process nervous system process nitrogen compound metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoside phosphate binding nucleoside phosphate biosynthetic process nucleoside phosphate metabolic process nucleotide binding nucleotide biosynthetic process nucleotide metabolic process olfactory behavior olfactory learning organelle membrane organelle organic cyclic compound binding organic cyclic compound biosynthetic process organic cyclic compound metabolic process organic substance biosynthetic process organic substance metabolic process organonitrogen compound biosynthetic process organonitrogen compound metabolic process organophosphate biosynthetic process organophosphate metabolic process phosphate-containing compound metabolic process phosphorus metabolic process phosphorus-oxygen lyase activity plasma membrane bounded cell projection plasma membrane region plasma membrane primary metabolic process protein binding purine nucleotide binding purine nucleotide biosynthetic process purine nucleotide metabolic process purine ribonucleoside triphosphate binding purine ribonucleotide binding purine ribonucleotide biosynthetic process purine ribonucleotide metabolic process purine-containing compound biosynthetic process purine-containing compound metabolic process regulation of biological process regulation of cellular process reproductive process response to alcohol response to chemical response to forskolin response to ketone response to lipid response to organic cyclic compound response to organic substance response to oxygen-containing compound response to stimulus ribonucleotide binding ribonucleotide biosynthetic process ribonucleotide metabolic process ribose phosphate biosynthetic process ribose phosphate metabolic process sensory perception of chemical stimulus sensory perception of smell sensory perception signal transduction single fertilization small molecule binding small molecule metabolic process sperm motility system process	GO:0000166 GO:0001539 GO:0003008 GO:0003341 GO:0003674 GO:0003824 GO:0004016 GO:0005488 GO:0005515 GO:0005516 GO:0005524 GO:0005575 GO:0005737 GO:0005794 GO:0005886 GO:0005929 GO:0006139 GO:0006163 GO:0006164 GO:0006171 GO:0006725 GO:0006753 GO:0006793 GO:0006796 GO:0006807 GO:0007017 GO:0007018 GO:0007165 GO:0007186 GO:0007188 GO:0007189 GO:0007338 GO:0007340 GO:0007600 GO:0007606 GO:0007608 GO:0007610 GO:0007611 GO:0007612 GO:0007635 GO:0008150 GO:0008152 GO:0008306 GO:0008355 GO:0009058 GO:0009117 GO:0009150 GO:0009152 GO:0009165 GO:0009187 GO:0009190 GO:0009259 GO:0009260 GO:0009566 GO:0009975 GO:0009987 GO:0010033 GO:0014070 GO:0016020 GO:0016829 GO:0016849 GO:0017076 GO:0018130 GO:0019438 GO:0019637 GO:0019693 GO:0022414 GO:0030317 GO:0030554 GO:0031090 GO:0031253 GO:0032501 GO:0032553 GO:0032555 GO:0032559 GO:0033993 GO:0034641 GO:0034654 GO:0035556 GO:0035639 GO:0036094 GO:0042048 GO:0042221 GO:0042995 GO:0043167 GO:0043168 GO:0043169 GO:0043226 GO:0043227 GO:0043229 GO:0043231 GO:0044237 GO:0044238 GO:0044249 GO:0044271 GO:0044281 GO:0046058 GO:0046390 GO:0046483 GO:0046872 GO:0048870 GO:0050789 GO:0050794 GO:0050877 GO:0050890 GO:0050896 GO:0051716 GO:0052652 GO:0055086 GO:0060170 GO:0060285 GO:0060294 GO:0065007 GO:0070887 GO:0071310 GO:0071396 GO:0071407 GO:0071704 GO:0072521 GO:0072522 GO:0090407 GO:0097159 GO:0097305 GO:0097306 GO:0097367 GO:0097722 GO:0098588 GO:0098590 GO:0110165 GO:0120025 GO:1901135 GO:1901137 GO:1901265 GO:1901293 GO:1901360 GO:1901362 GO:1901363 GO:1901564 GO:1901566 GO:1901576 GO:1901654 GO:1901655 GO:1901700 GO:1901701 GO:1904321 GO:1904322
111	adenylate cyclase 5	ADCY5	Homo sapiens (human)	9606			ATP binding G protein-coupled adenosine receptor signaling pathway G protein-coupled purinergic receptor signaling pathway G protein-coupled receptor signaling pathway adenyl nucleotide binding adenyl ribonucleotide binding adenylate cyclase activity adenylate cyclase binding adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating dopamine receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting dopamine receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway anion binding aromatic compound biosynthetic process behavior binding biological regulation biological_process biosynthetic process cAMP biosynthetic process cAMP metabolic process carbohydrate derivative binding carbohydrate derivative biosynthetic process carbohydrate derivative metabolic process catalytic activity cation binding cell projection cell surface receptor signaling pathway cellular anatomical entity cellular aromatic compound metabolic process cellular biosynthetic process cellular metabolic process cellular nitrogen compound biosynthetic process cellular nitrogen compound metabolic process cellular process cellular response to alcohol cellular response to chemical stimulus cellular response to forskolin cellular response to ketone cellular response to lipid cellular response to organic cyclic compound cellular response to organic substance cellular response to oxygen-containing compound cellular response to stimulus cellular_component cilium cyclase activity cyclic nucleotide biosynthetic process cyclic nucleotide metabolic process cyclic purine nucleotide metabolic process dopamine receptor signaling pathway enzyme binding heterocycle biosynthetic process heterocycle metabolic process heterocyclic compound binding intracellular signal transduction ion binding locomotory behavior lyase activity membrane-bounded organelle membrane metabolic process metal ion binding molecular_function multicellular organismal process nervous system process neuromuscular process controlling balance neuromuscular process nitrogen compound metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoside phosphate binding nucleoside phosphate biosynthetic process nucleoside phosphate metabolic process nucleotide binding nucleotide biosynthetic process nucleotide metabolic process organelle organic cyclic compound binding organic cyclic compound biosynthetic process organic cyclic compound metabolic process organic substance biosynthetic process organic substance metabolic process organonitrogen compound biosynthetic process organonitrogen compound metabolic process organophosphate biosynthetic process organophosphate metabolic process phosphate-containing compound metabolic process phosphorus metabolic process phosphorus-oxygen lyase activity plasma membrane bounded cell projection plasma membrane positive regulation of cytosolic calcium ion concentration primary metabolic process protein binding purine nucleotide binding purine nucleotide biosynthetic process purine nucleotide metabolic process purine ribonucleoside triphosphate binding purine ribonucleotide binding purine ribonucleotide biosynthetic process purine ribonucleotide metabolic process purine-containing compound biosynthetic process purine-containing compound metabolic process purinergic nucleotide receptor signaling pathway regulation of biological process regulation of biological quality regulation of cell communication regulation of cellular localization regulation of cellular process regulation of establishment of protein localization regulation of hormone levels regulation of hormone secretion regulation of insulin secretion involved in cellular response to glucose stimulus regulation of insulin secretion regulation of localization regulation of peptide hormone secretion regulation of peptide secretion regulation of peptide transport regulation of protein localization regulation of protein secretion regulation of protein transport regulation of secretion by cell regulation of secretion regulation of signaling regulation of transport response to alcohol response to chemical response to forskolin response to ketone response to lipid response to organic cyclic compound response to organic substance response to oxygen-containing compound response to stimulus ribonucleotide binding ribonucleotide biosynthetic process ribonucleotide metabolic process ribose phosphate biosynthetic process ribose phosphate metabolic process scaffold protein binding signal transduction small molecule binding small molecule metabolic process system process	GO:0000166 GO:0001973 GO:0002791 GO:0003008 GO:0003674 GO:0003824 GO:0004016 GO:0005488 GO:0005515 GO:0005524 GO:0005575 GO:0005886 GO:0005929 GO:0006139 GO:0006163 GO:0006164 GO:0006171 GO:0006725 GO:0006753 GO:0006793 GO:0006796 GO:0006807 GO:0007165 GO:0007166 GO:0007186 GO:0007188 GO:0007189 GO:0007191 GO:0007193 GO:0007195 GO:0007204 GO:0007212 GO:0007610 GO:0007626 GO:0008150 GO:0008152 GO:0008179 GO:0009058 GO:0009117 GO:0009150 GO:0009152 GO:0009165 GO:0009187 GO:0009190 GO:0009259 GO:0009260 GO:0009975 GO:0009987 GO:0010033 GO:0010646 GO:0010817 GO:0014070 GO:0016020 GO:0016829 GO:0016849 GO:0017076 GO:0018130 GO:0019438 GO:0019637 GO:0019693 GO:0019899 GO:0023051 GO:0030554 GO:0032501 GO:0032553 GO:0032555 GO:0032559 GO:0032879 GO:0032880 GO:0033993 GO:0034641 GO:0034654 GO:0035556 GO:0035588 GO:0035590 GO:0035639 GO:0036094 GO:0042221 GO:0042995 GO:0043167 GO:0043168 GO:0043169 GO:0043226 GO:0043227 GO:0044237 GO:0044238 GO:0044249 GO:0044271 GO:0044281 GO:0046058 GO:0046390 GO:0046483 GO:0046872 GO:0046883 GO:0050708 GO:0050789 GO:0050794 GO:0050796 GO:0050877 GO:0050885 GO:0050896 GO:0050905 GO:0051046 GO:0051049 GO:0051223 GO:0051716 GO:0052652 GO:0055086 GO:0060341 GO:0061178 GO:0065007 GO:0065008 GO:0070201 GO:0070887 GO:0071310 GO:0071396 GO:0071407 GO:0071704 GO:0072521 GO:0072522 GO:0090087 GO:0090276 GO:0090407 GO:0097110 GO:0097159 GO:0097305 GO:0097306 GO:0097367 GO:0110165 GO:0120025 GO:1901135 GO:1901137 GO:1901265 GO:1901293 GO:1901360 GO:1901362 GO:1901363 GO:1901564 GO:1901566 GO:1901576 GO:1901654 GO:1901655 GO:1901700 GO:1901701 GO:1903530 GO:1904321 GO:1904322
112	adenylate cyclase 6	ADCY6	Homo sapiens (human)	9606			ATP binding G protein-coupled receptor signaling pathway actin-based cell projection adenyl nucleotide binding adenyl ribonucleotide binding adenylate cyclase activity adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating dopamine receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway anion binding aromatic compound biosynthetic process binding biological regulation biological_process biosynthetic process blood vessel diameter maintenance cAMP biosynthetic process cAMP metabolic process carbohydrate derivative binding carbohydrate derivative biosynthetic process carbohydrate derivative metabolic process catalytic activity cation binding cell projection cellular anatomical entity cellular aromatic compound metabolic process cellular biosynthetic process cellular metabolic process cellular nitrogen compound biosynthetic process cellular nitrogen compound metabolic process cellular process cellular response to alcohol cellular response to catecholamine stimulus cellular response to chemical stimulus cellular response to endogenous stimulus cellular response to forskolin cellular response to hormone stimulus cellular response to ketone cellular response to lipid cellular response to monoamine stimulus cellular response to nitrogen compound cellular response to organic cyclic compound cellular response to organic substance cellular response to organonitrogen compound cellular response to oxygen-containing compound cellular response to peptide hormone stimulus cellular response to peptide cellular response to prostaglandin E stimulus cellular response to prostaglandin stimulus cellular response to stimulus cellular response to vasopressin cellular_component chemical homeostasis cilium circulatory system process cyclase activity cyclic nucleotide biosynthetic process cyclic nucleotide metabolic process cyclic purine nucleotide metabolic process dopamine receptor signaling pathway enzyme binding heterocycle biosynthetic process heterocycle metabolic process heterocyclic compound binding homeostatic process intracellular signal transduction ion binding kinase binding lyase activity membrane-bounded organelle membrane metabolic process metal ion binding molecular_function multicellular organismal process multicellular organismal-level chemical homeostasis multicellular organismal-level homeostasis multicellular organismal-level water homeostasis negative regulation of biological process negative regulation of cell projection organization negative regulation of cellular component organization negative regulation of cellular process negative regulation of neuron projection development negative regulation of urine volume neuron projection nitrogen compound metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoside phosphate binding nucleoside phosphate biosynthetic process nucleoside phosphate metabolic process nucleotide binding nucleotide biosynthetic process nucleotide metabolic process organelle organic cyclic compound binding organic cyclic compound biosynthetic process organic cyclic compound metabolic process organic substance biosynthetic process organic substance metabolic process organonitrogen compound biosynthetic process organonitrogen compound metabolic process organophosphate biosynthetic process organophosphate metabolic process phosphate-containing compound metabolic process phosphorus metabolic process phosphorus-oxygen lyase activity plasma membrane bounded cell projection plasma membrane primary metabolic process protein binding protein kinase C binding protein kinase binding purine nucleotide binding purine nucleotide biosynthetic process purine nucleotide metabolic process purine ribonucleoside triphosphate binding purine ribonucleotide binding purine ribonucleotide biosynthetic process purine ribonucleotide metabolic process purine-containing compound biosynthetic process purine-containing compound metabolic process regulation of anatomical structure size regulation of biological process regulation of biological quality regulation of body fluid levels regulation of cell projection organization regulation of cellular component organization regulation of cellular process regulation of neuron projection development regulation of plasma membrane bounded cell projection organization regulation of tube diameter regulation of tube size regulation of urine volume renal system process renal water homeostasis response to alcohol response to catecholamine response to chemical response to endogenous stimulus response to forskolin response to hormone response to ketone response to lipid response to monoamine response to nitrogen compound response to organic cyclic compound response to organic substance response to organonitrogen compound response to oxygen-containing compound response to peptide hormone response to peptide response to prostaglandin E response to prostaglandin response to stimulus response to vasopressin ribonucleotide binding ribonucleotide biosynthetic process ribonucleotide metabolic process ribose phosphate biosynthetic process ribose phosphate metabolic process signal transduction small molecule binding small molecule metabolic process stereocilium system process vascular process in circulatory system	GO:0000166 GO:0003008 GO:0003013 GO:0003014 GO:0003018 GO:0003091 GO:0003674 GO:0003824 GO:0004016 GO:0005080 GO:0005488 GO:0005515 GO:0005524 GO:0005575 GO:0005886 GO:0005929 GO:0006139 GO:0006163 GO:0006164 GO:0006171 GO:0006725 GO:0006753 GO:0006793 GO:0006796 GO:0006807 GO:0007165 GO:0007186 GO:0007188 GO:0007189 GO:0007191 GO:0007193 GO:0007212 GO:0008150 GO:0008152 GO:0009058 GO:0009117 GO:0009150 GO:0009152 GO:0009165 GO:0009187 GO:0009190 GO:0009259 GO:0009260 GO:0009719 GO:0009725 GO:0009975 GO:0009987 GO:0010033 GO:0010243 GO:0010975 GO:0010977 GO:0014070 GO:0016020 GO:0016829 GO:0016849 GO:0017076 GO:0018130 GO:0019438 GO:0019637 GO:0019693 GO:0019899 GO:0019900 GO:0019901 GO:0030554 GO:0031344 GO:0031345 GO:0032420 GO:0032501 GO:0032553 GO:0032555 GO:0032559 GO:0032870 GO:0033993 GO:0034641 GO:0034654 GO:0034694 GO:0034695 GO:0035150 GO:0035296 GO:0035556 GO:0035639 GO:0035809 GO:0035811 GO:0036094 GO:0042221 GO:0042592 GO:0042995 GO:0043005 GO:0043167 GO:0043168 GO:0043169 GO:0043226 GO:0043227 GO:0043434 GO:0044237 GO:0044238 GO:0044249 GO:0044271 GO:0044281 GO:0046058 GO:0046390 GO:0046483 GO:0046872 GO:0048519 GO:0048523 GO:0048871 GO:0048878 GO:0050789 GO:0050794 GO:0050878 GO:0050891 GO:0050896 GO:0051128 GO:0051129 GO:0051716 GO:0052652 GO:0055086 GO:0065007 GO:0065008 GO:0070887 GO:0071310 GO:0071375 GO:0071379 GO:0071380 GO:0071396 GO:0071407 GO:0071417 GO:0071495 GO:0071704 GO:0071867 GO:0071868 GO:0071869 GO:0071870 GO:0072521 GO:0072522 GO:0090066 GO:0090407 GO:0097159 GO:0097305 GO:0097306 GO:0097367 GO:0097746 GO:0098858 GO:0110165 GO:0120025 GO:0120035 GO:0140962 GO:1901135 GO:1901137 GO:1901265 GO:1901293 GO:1901360 GO:1901362 GO:1901363 GO:1901564 GO:1901566 GO:1901576 GO:1901652 GO:1901653 GO:1901654 GO:1901655 GO:1901698 GO:1901699 GO:1901700 GO:1901701 GO:1904116 GO:1904117 GO:1904321 GO:1904322
113	adenylate cyclase 7	ADCY7	Homo sapiens (human)	9606			ATP binding G protein-coupled receptor signaling pathway adenyl nucleotide binding adenyl ribonucleotide binding adenylate cyclase activity adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway anion binding aromatic compound biosynthetic process binding biological regulation biological_process biosynthetic process cAMP biosynthetic process cAMP metabolic process carbohydrate derivative binding carbohydrate derivative biosynthetic process carbohydrate derivative metabolic process catalytic activity cation binding cellular anatomical entity cellular aromatic compound metabolic process cellular biosynthetic process cellular metabolic process cellular nitrogen compound biosynthetic process cellular nitrogen compound metabolic process cellular process cellular response to alcohol cellular response to chemical stimulus cellular response to ethanol cellular response to inorganic substance cellular response to lithium ion cellular response to metal ion cellular response to organic substance cellular response to oxygen-containing compound cellular response to salt cellular response to stimulus cellular_component cyclase activity cyclic nucleotide biosynthetic process cyclic nucleotide metabolic process cyclic purine nucleotide metabolic process heterocycle biosynthetic process heterocycle metabolic process heterocyclic compound binding intracellular signal transduction ion binding lyase activity maternal process involved in female pregnancy membrane metabolic process metal ion binding molecular_function multicellular organismal reproductive process negative regulation of biological process negative regulation of biosynthetic process negative regulation of cellular biosynthetic process negative regulation of cellular metabolic process negative regulation of cellular process negative regulation of cytokine production involved in inflammatory response negative regulation of cytokine production negative regulation of gene expression negative regulation of macromolecule biosynthetic process negative regulation of macromolecule metabolic process negative regulation of metabolic process negative regulation of multicellular organismal process nitrogen compound metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoside phosphate binding nucleoside phosphate biosynthetic process nucleoside phosphate metabolic process nucleotide binding nucleotide biosynthetic process nucleotide metabolic process organic cyclic compound binding organic cyclic compound biosynthetic process organic cyclic compound metabolic process organic substance biosynthetic process organic substance metabolic process organonitrogen compound biosynthetic process organonitrogen compound metabolic process organophosphate biosynthetic process organophosphate metabolic process phosphate-containing compound metabolic process phosphorus metabolic process phosphorus-oxygen lyase activity plasma membrane primary metabolic process purine nucleotide binding purine nucleotide biosynthetic process purine nucleotide metabolic process purine ribonucleoside triphosphate binding purine ribonucleotide binding purine ribonucleotide biosynthetic process purine ribonucleotide metabolic process purine-containing compound biosynthetic process purine-containing compound metabolic process regulation of adaptive immune response regulation of biological process regulation of biosynthetic process regulation of cellular biosynthetic process regulation of cellular metabolic process regulation of cellular process regulation of cytokine production involved in inflammatory response regulation of cytokine production regulation of gene expression regulation of immune response regulation of immune system process regulation of macromolecule biosynthetic process regulation of macromolecule metabolic process regulation of metabolic process regulation of multicellular organismal process regulation of response to stimulus reproductive process response to alcohol response to chemical response to ethanol response to inorganic substance response to lithium ion response to metal ion response to organic substance response to oxygen-containing compound response to salt response to stimulus ribonucleotide binding ribonucleotide biosynthetic process ribonucleotide metabolic process ribose phosphate biosynthetic process ribose phosphate metabolic process signal transduction small molecule binding small molecule metabolic process	GO:0000166 GO:0001817 GO:0001818 GO:0002682 GO:0002819 GO:0003674 GO:0003824 GO:0004016 GO:0005488 GO:0005524 GO:0005575 GO:0005886 GO:0006139 GO:0006163 GO:0006164 GO:0006171 GO:0006725 GO:0006753 GO:0006793 GO:0006796 GO:0006807 GO:0007165 GO:0007186 GO:0007188 GO:0007189 GO:0007193 GO:0008150 GO:0008152 GO:0009058 GO:0009117 GO:0009150 GO:0009152 GO:0009165 GO:0009187 GO:0009190 GO:0009259 GO:0009260 GO:0009889 GO:0009890 GO:0009892 GO:0009975 GO:0009987 GO:0010033 GO:0010035 GO:0010038 GO:0010226 GO:0010468 GO:0010556 GO:0010558 GO:0010605 GO:0010629 GO:0016020 GO:0016829 GO:0016849 GO:0017076 GO:0018130 GO:0019222 GO:0019438 GO:0019637 GO:0019693 GO:0022414 GO:0030554 GO:0031323 GO:0031324 GO:0031326 GO:0031327 GO:0032553 GO:0032555 GO:0032559 GO:0034641 GO:0034654 GO:0035556 GO:0035639 GO:0036094 GO:0042221 GO:0043167 GO:0043168 GO:0043169 GO:0044237 GO:0044238 GO:0044249 GO:0044271 GO:0044281 GO:0045471 GO:0046058 GO:0046390 GO:0046483 GO:0046872 GO:0048519 GO:0048523 GO:0048583 GO:0048609 GO:0050776 GO:0050789 GO:0050794 GO:0050896 GO:0051239 GO:0051241 GO:0051716 GO:0052652 GO:0055086 GO:0060135 GO:0060255 GO:0065007 GO:0070887 GO:0071241 GO:0071248 GO:0071285 GO:0071310 GO:0071361 GO:0071704 GO:0072521 GO:0072522 GO:0090407 GO:0097159 GO:0097305 GO:0097306 GO:0097367 GO:0110165 GO:1900015 GO:1900016 GO:1901135 GO:1901137 GO:1901265 GO:1901293 GO:1901360 GO:1901362 GO:1901363 GO:1901564 GO:1901566 GO:1901576 GO:1901700 GO:1901701 GO:1902074 GO:1902075
114	adenylate cyclase 8	ADCY8	Homo sapiens (human)	9606			ATP binding G protein-coupled opioid receptor signaling pathway G protein-coupled receptor signaling pathway Schaffer collateral - CA1 synapse actin binding actin cytoskeleton activation of protein kinase A activity activation of protein kinase activity adenyl nucleotide binding adenyl ribonucleotide binding adenylate cyclase activity adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway anion binding apical plasma membrane aromatic compound biosynthetic process axon basolateral plasma membrane behavior binding biological regulation biological_process biosynthetic process bounding membrane of organelle cAMP biosynthetic process cAMP metabolic process calcium ion homeostasis calcium- and calmodulin-responsive adenylate cyclase activity calmodulin binding carbohydrate derivative binding carbohydrate derivative biosynthetic process carbohydrate derivative metabolic process carbohydrate homeostasis carbohydrate mediated signaling catalytic activity cation binding caveola cell body membrane cell junction cell projection cellular anatomical entity cellular aromatic compound metabolic process cellular biosynthetic process cellular component assembly cellular component organization or biogenesis cellular component organization cellular homeostasis cellular metabolic process cellular nitrogen compound biosynthetic process cellular nitrogen compound metabolic process cellular process cellular response to alcohol cellular response to alkaloid cellular response to calcium ion cellular response to carbohydrate stimulus cellular response to chemical stimulus cellular response to endogenous stimulus cellular response to forskolin cellular response to glucagon stimulus cellular response to glucose stimulus cellular response to hexose stimulus cellular response to hormone stimulus cellular response to inorganic substance cellular response to isoquinoline alkaloid cellular response to ketone cellular response to lipid cellular response to metal ion cellular response to monosaccharide stimulus cellular response to morphine cellular response to nitrogen compound cellular response to organic cyclic compound cellular response to organic substance cellular response to organonitrogen compound cellular response to oxygen-containing compound cellular response to peptide hormone stimulus cellular response to peptide cellular response to salt cellular response to stimulus cellular_component chemical homeostasis clathrin-coated pit clathrin-coated vesicle membrane coated vesicle membrane cognition cyclase activity cyclic nucleotide biosynthetic process cyclic nucleotide metabolic process cyclic purine nucleotide metabolic process cytoplasmic vesicle membrane cytoskeletal protein binding cytoskeleton defense response dendrite enzyme binding excitatory synapse glucose homeostasis glucose mediated signaling pathway glutamatergic synapse heterocycle biosynthetic process heterocycle metabolic process heterocyclic compound binding hexose mediated signaling hippocampal mossy fiber to CA3 synapse homeostatic process identical protein binding inflammatory response inorganic ion homeostasis intracellular calcium ion homeostasis intracellular chemical homeostasis intracellular glucose homeostasis intracellular monoatomic cation homeostasis intracellular monoatomic ion homeostasis intracellular non-membrane-bounded organelle intracellular organelle intracellular signal transduction ion binding learning or memory locomotory behavior long-term memory lyase activity membrane microdomain membrane raft membrane memory metabolic process metal ion binding modulation of chemical synaptic transmission molecular_function monoatomic cation homeostasis monoatomic ion homeostasis multicellular organismal process nervous system process neuroinflammatory response neuron projection neuron to neuron synapse neuronal cell body membrane nitrogen compound metabolic process non-membrane-bounded organelle nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoside phosphate binding nucleoside phosphate biosynthetic process nucleoside phosphate metabolic process nucleotide binding nucleotide biosynthetic process nucleotide metabolic process organelle membrane organelle organic cyclic compound binding organic cyclic compound biosynthetic process organic cyclic compound metabolic process organic substance biosynthetic process organic substance metabolic process organonitrogen compound biosynthetic process organonitrogen compound metabolic process organophosphate biosynthetic process organophosphate metabolic process phosphatase binding phosphate-containing compound metabolic process phosphorus metabolic process phosphorus-oxygen lyase activity plasma membrane bounded cell projection plasma membrane raft plasma membrane region plasma membrane positive regulation of CREB transcription factor activity positive regulation of DNA-binding transcription factor activity positive regulation of biological process positive regulation of catalytic activity positive regulation of cell communication positive regulation of cellular metabolic process positive regulation of cellular process positive regulation of cytosolic calcium ion concentration positive regulation of establishment of protein localization positive regulation of hormone secretion positive regulation of insulin secretion involved in cellular response to glucose stimulus positive regulation of insulin secretion positive regulation of kinase activity positive regulation of long-term synaptic depression positive regulation of long-term synaptic potentiation positive regulation of macromolecule metabolic process positive regulation of metabolic process positive regulation of molecular function positive regulation of nitrogen compound metabolic process positive regulation of peptide hormone secretion positive regulation of peptide secretion positive regulation of phosphate metabolic process positive regulation of phosphorus metabolic process positive regulation of phosphorylation positive regulation of protein kinase activity positive regulation of protein localization positive regulation of protein metabolic process positive regulation of protein modification process positive regulation of protein phosphorylation positive regulation of protein secretion positive regulation of protein transport positive regulation of secretion by cell positive regulation of secretion positive regulation of signaling positive regulation of synaptic plasticity positive regulation of synaptic transmission positive regulation of transferase activity positive regulation of transport postsynaptic density postsynaptic specialization presynaptic active zone presynaptic membrane primary metabolic process protein binding protein complex oligomerization protein dimerization activity protein heterodimerization activity protein homodimerization activity protein homooligomerization protein phosphatase 2A binding protein phosphatase binding protein-containing complex assembly protein-containing complex organization purine nucleotide binding purine nucleotide biosynthetic process purine nucleotide metabolic process purine ribonucleoside triphosphate binding purine ribonucleotide binding purine ribonucleotide biosynthetic process purine ribonucleotide metabolic process purine-containing compound biosynthetic process purine-containing compound metabolic process regulation of DNA-binding transcription factor activity regulation of DNA-templated transcription regulation of RNA biosynthetic process regulation of RNA metabolic process regulation of biological process regulation of biological quality regulation of biosynthetic process regulation of catalytic activity regulation of cell communication regulation of cellular biosynthetic process regulation of cellular localization regulation of cellular metabolic process regulation of cellular process regulation of cellular response to stress regulation of cytosolic calcium ion concentration regulation of establishment of protein localization regulation of gene expression regulation of hormone levels regulation of hormone secretion regulation of insulin secretion involved in cellular response to glucose stimulus regulation of insulin secretion regulation of kinase activity regulation of localization regulation of long-term synaptic depression regulation of long-term synaptic potentiation regulation of macromolecule biosynthetic process regulation of macromolecule metabolic process regulation of metabolic process regulation of molecular function regulation of nitrogen compound metabolic process regulation of nucleobase-containing compound metabolic process regulation of peptide hormone secretion regulation of peptide secretion regulation of peptide transport regulation of phosphate metabolic process regulation of phosphorus metabolic process regulation of phosphorylation regulation of primary metabolic process regulation of protein kinase activity regulation of protein localization regulation of protein metabolic process regulation of protein modification process regulation of protein phosphorylation regulation of protein secretion regulation of protein transport regulation of response to stimulus regulation of response to stress regulation of secretion by cell regulation of secretion regulation of signaling regulation of synaptic plasticity regulation of trans-synaptic signaling regulation of transferase activity regulation of transport response to alcohol response to alkaloid response to calcium ion response to carbohydrate response to chemical response to endogenous stimulus response to forskolin response to glucagon response to glucose response to hexose response to hormone response to inorganic substance response to isoquinoline alkaloid response to ketone response to lipid response to metal ion response to monosaccharide response to morphine response to nitrogen compound response to organic cyclic compound response to organic substance response to organonitrogen compound response to oxygen-containing compound response to peptide hormone response to peptide response to salt response to stimulus response to stress ribonucleotide binding ribonucleotide biosynthetic process ribonucleotide metabolic process ribose phosphate biosynthetic process ribose phosphate metabolic process signal transduction small molecule binding small molecule metabolic process sugar mediated signaling pathway synapse synaptic membrane system process vesicle membrane	GO:0000166 GO:0001678 GO:0001932 GO:0001934 GO:0002791 GO:0002793 GO:0003008 GO:0003674 GO:0003779 GO:0003824 GO:0004016 GO:0005488 GO:0005515 GO:0005516 GO:0005524 GO:0005575 GO:0005856 GO:0005886 GO:0005901 GO:0005905 GO:0006139 GO:0006163 GO:0006164 GO:0006171 GO:0006355 GO:0006725 GO:0006753 GO:0006793 GO:0006796 GO:0006807 GO:0006873 GO:0006874 GO:0006950 GO:0006952 GO:0006954 GO:0007165 GO:0007186 GO:0007188 GO:0007189 GO:0007204 GO:0007610 GO:0007611 GO:0007613 GO:0007616 GO:0007626 GO:0008092 GO:0008150 GO:0008152 GO:0008294 GO:0009058 GO:0009117 GO:0009150 GO:0009152 GO:0009165 GO:0009187 GO:0009190 GO:0009259 GO:0009260 GO:0009719 GO:0009725 GO:0009743 GO:0009746 GO:0009749 GO:0009756 GO:0009757 GO:0009889 GO:0009893 GO:0009975 GO:0009987 GO:0010033 GO:0010035 GO:0010038 GO:0010182 GO:0010243 GO:0010255 GO:0010468 GO:0010556 GO:0010562 GO:0010604 GO:0010646 GO:0010647 GO:0010817 GO:0012506 GO:0014069 GO:0014070 GO:0014072 GO:0015629 GO:0016020 GO:0016043 GO:0016323 GO:0016324 GO:0016829 GO:0016849 GO:0017076 GO:0018130 GO:0019219 GO:0019220 GO:0019222 GO:0019438 GO:0019637 GO:0019693 GO:0019725 GO:0019899 GO:0019902 GO:0019903 GO:0022607 GO:0023051 GO:0023056 GO:0030003 GO:0030054 GO:0030424 GO:0030425 GO:0030554 GO:0030659 GO:0030662 GO:0030665 GO:0031090 GO:0031323 GO:0031325 GO:0031326 GO:0031399 GO:0031401 GO:0031915 GO:0032024 GO:0032147 GO:0032501 GO:0032553 GO:0032555 GO:0032559 GO:0032793 GO:0032809 GO:0032870 GO:0032879 GO:0032880 GO:0033500 GO:0033674 GO:0033762 GO:0033993 GO:0034199 GO:0034284 GO:0034641 GO:0034654 GO:0035556 GO:0035639 GO:0035774 GO:0036094 GO:0038003 GO:0042221 GO:0042325 GO:0042327 GO:0042592 GO:0042593 GO:0042734 GO:0042802 GO:0042803 GO:0042995 GO:0043005 GO:0043085 GO:0043167 GO:0043168 GO:0043169 GO:0043226 GO:0043228 GO:0043229 GO:0043232 GO:0043278 GO:0043279 GO:0043434 GO:0043549 GO:0043933 GO:0044093 GO:0044237 GO:0044238 GO:0044249 GO:0044271 GO:0044281 GO:0044298 GO:0044853 GO:0045121 GO:0045202 GO:0045859 GO:0045860 GO:0045937 GO:0046058 GO:0046390 GO:0046483 GO:0046872 GO:0046883 GO:0046887 GO:0046982 GO:0046983 GO:0048167 GO:0048518 GO:0048522 GO:0048583 GO:0048786 GO:0048878 GO:0050708 GO:0050714 GO:0050789 GO:0050790 GO:0050794 GO:0050796 GO:0050801 GO:0050804 GO:0050806 GO:0050877 GO:0050890 GO:0050896 GO:0051046 GO:0051047 GO:0051049 GO:0051050 GO:0051090 GO:0051091 GO:0051171 GO:0051173 GO:0051174 GO:0051222 GO:0051223 GO:0051246 GO:0051247 GO:0051252 GO:0051259 GO:0051260 GO:0051338 GO:0051347 GO:0051480 GO:0051592 GO:0051716 GO:0051721 GO:0052652 GO:0055074 GO:0055080 GO:0055082 GO:0055086 GO:0060076 GO:0060255 GO:0060341 GO:0061178 GO:0065003 GO:0065007 GO:0065008 GO:0065009 GO:0070201 GO:0070887 GO:0071241 GO:0071248 GO:0071277 GO:0071310 GO:0071312 GO:0071315 GO:0071317 GO:0071322 GO:0071326 GO:0071331 GO:0071333 GO:0071375 GO:0071377 GO:0071396 GO:0071407 GO:0071417 GO:0071495 GO:0071704 GO:0071840 GO:0072521 GO:0072522 GO:0080090 GO:0080134 GO:0080135 GO:0090087 GO:0090276 GO:0090277 GO:0090407 GO:0097060 GO:0097159 GO:0097305 GO:0097306 GO:0097367 GO:0098588 GO:0098590 GO:0098685 GO:0098686 GO:0098771 GO:0098857 GO:0098978 GO:0098984 GO:0099177 GO:0099572 GO:0110165 GO:0120025 GO:0150076 GO:1900271 GO:1900273 GO:1900452 GO:1900454 GO:1901135 GO:1901137 GO:1901265 GO:1901293 GO:1901360 GO:1901362 GO:1901363 GO:1901564 GO:1901566 GO:1901576 GO:1901652 GO:1901653 GO:1901654 GO:1901655 GO:1901698 GO:1901699 GO:1901700 GO:1901701 GO:1902074 GO:1902075 GO:1903530 GO:1903532 GO:1903829 GO:1904321 GO:1904322 GO:1904951 GO:2001141
115	adenylate cyclase 9	ADCY9	Homo sapiens (human)	9606			ATP binding G protein-coupled receptor signaling pathway adenyl nucleotide binding adenyl ribonucleotide binding adenylate cyclase activity

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