GlyCosmos Portal

GlyCosmos Genes

Integrated list of glycan-related genes extracted KEGG GENES Database, UniProt, GlycoGene Database (GGDB), Plant GARDEN and FlyGlycoDB. Glycan-related genes including glycosyltransferase, hydrolase activity (acting on glycosyl bonds), carbohydrate metabolic process, etc .

Source	Last Updated
FlyGlycoDB	March 25, 2024
GlycoGene Database (GGDB)	January 26, 2018
KEGG GENES Database	September 20, 2023
Plant GARDEN	May 28, 2020
UniProt	October 29, 2024

Selecting the function you want to look up from the categories displays a list narrowed down to glycan-related genes with that function (Gene Ontology).

Catalytic activity

glycosyltransferase activity

hydrolase activity, acting on glycosyl bonds

Binding

carbohydrate binding

Response to carbohydrate

Primary metabolic process

Displaying entries **1 - 25** of **9988** in total

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Gene ID	Gene Name	Gene Symbol	Organism	Taxonomy ID	Disease Ontology	Disease Ontology ID	Gene Ontology ▲	Gene Ontology ID
5471	phosphoribosyl pyrophosphate amidotransferase	PPAT Aliases: GPAT PRAT	Homo sapiens (human)	9606	alcohol dependence alcohol use disorder breast cancer chromophobe renal cell carcinoma clear cell renal cell carcinoma collecting duct carcinoma hepatoblastoma hepatocellular carcinoma liver cancer ovarian cancer ovarian carcinoma papillary renal cell carcinoma renal carcinoma renal cell carcinoma sarcomatoid renal cell carcinoma stomach cancer stomach carcinoma	DOID:0050741 DOID:10534 DOID:1574 DOID:1612 DOID:2394 DOID:3571 DOID:4001 DOID:4450 DOID:4451 DOID:4464 DOID:4465 DOID:4467 DOID:4471 DOID:4473 DOID:5517 DOID:684 DOID:687	'de novo' AMP biosynthetic process 'de novo' IMP biosynthetic process 'de novo' XMP biosynthetic process 4 iron, 4 sulfur cluster binding AMP biosynthetic process AMP metabolic process GMP biosynthetic process GMP metabolic process IMP biosynthetic process IMP metabolic process XMP biosynthetic process XMP metabolic process alpha-amino acid metabolic process amidophosphoribosyltransferase activity amino acid metabolic process aromatic compound biosynthetic process binding biological_process biosynthetic process carbohydrate derivative biosynthetic process carbohydrate derivative metabolic process carboxylic acid metabolic process catalytic activity cation binding cellular anatomical entity cellular aromatic compound metabolic process cellular biosynthetic process cellular metabolic process cellular nitrogen compound biosynthetic process cellular nitrogen compound metabolic process cellular process cellular_component cytosol glutamine family amino acid metabolic process glutamine metabolic process glycosyltransferase activity heterocycle biosynthetic process heterocycle metabolic process ion binding iron-sulfur cluster binding metabolic process metal cluster binding metal ion binding molecular_function nitrogen compound metabolic process nucleobase biosynthetic process nucleobase metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoside monophosphate biosynthetic process nucleoside monophosphate metabolic process nucleoside phosphate biosynthetic process nucleoside phosphate metabolic process nucleotide biosynthetic process nucleotide metabolic process organic acid metabolic process organic cyclic compound biosynthetic process organic cyclic compound metabolic process organic substance biosynthetic process organic substance metabolic process organonitrogen compound biosynthetic process organonitrogen compound metabolic process organophosphate biosynthetic process organophosphate metabolic process oxoacid metabolic process pentosyltransferase activity phosphate-containing compound metabolic process phosphorus metabolic process primary metabolic process protein binding purine nucleobase biosynthetic process purine nucleobase metabolic process purine nucleoside monophosphate biosynthetic process purine nucleoside monophosphate metabolic process purine nucleotide biosynthetic process purine nucleotide metabolic process purine ribonucleoside monophosphate biosynthetic process purine ribonucleoside monophosphate metabolic process purine ribonucleotide biosynthetic process purine ribonucleotide metabolic process purine-containing compound biosynthetic process purine-containing compound metabolic process ribonucleoside monophosphate biosynthetic process ribonucleoside monophosphate metabolic process ribonucleotide biosynthetic process ribonucleotide metabolic process ribose phosphate biosynthetic process ribose phosphate metabolic process small molecule metabolic process transferase activity	GO:0003674 GO:0003824 GO:0004044 GO:0005488 GO:0005515 GO:0005575 GO:0005829 GO:0006082 GO:0006139 GO:0006144 GO:0006163 GO:0006164 GO:0006167 GO:0006177 GO:0006188 GO:0006189 GO:0006520 GO:0006541 GO:0006725 GO:0006753 GO:0006793 GO:0006796 GO:0006807 GO:0008150 GO:0008152 GO:0009058 GO:0009064 GO:0009112 GO:0009113 GO:0009117 GO:0009123 GO:0009124 GO:0009126 GO:0009127 GO:0009150 GO:0009152 GO:0009156 GO:0009161 GO:0009165 GO:0009167 GO:0009168 GO:0009259 GO:0009260 GO:0009987 GO:0016740 GO:0016757 GO:0016763 GO:0018130 GO:0019438 GO:0019637 GO:0019693 GO:0019752 GO:0034641 GO:0034654 GO:0043167 GO:0043169 GO:0043436 GO:0044208 GO:0044237 GO:0044238 GO:0044249 GO:0044271 GO:0044281 GO:0046033 GO:0046037 GO:0046040 GO:0046112 GO:0046390 GO:0046483 GO:0046872 GO:0051536 GO:0051539 GO:0051540 GO:0055086 GO:0071704 GO:0072521 GO:0072522 GO:0090407 GO:0097292 GO:0097293 GO:0097294 GO:0110165 GO:1901135 GO:1901137 GO:1901293 GO:1901360 GO:1901362 GO:1901564 GO:1901566 GO:1901576 GO:1901605
5198	phosphoribosylformylglycinamidine synthase	PFAS	Homo sapiens (human)	9606			'de novo' AMP biosynthetic process 'de novo' IMP biosynthetic process 'de novo' XMP biosynthetic process AMP biosynthetic process AMP metabolic process ATP binding GMP biosynthetic process GMP metabolic process IMP biosynthetic process IMP metabolic process XMP biosynthetic process XMP metabolic process adenyl nucleotide binding adenyl ribonucleotide binding alpha-amino acid metabolic process amino acid metabolic process anatomical structure development anion binding anterior head development aromatic compound biosynthetic process binding biological_process biosynthetic process carbohydrate derivative binding carbohydrate derivative biosynthetic process carbohydrate derivative metabolic process carbon-nitrogen ligase activity, with glutamine as amido-N-donor carboxylic acid metabolic process catalytic activity cation binding cellular anatomical entity cellular aromatic compound metabolic process cellular biosynthetic process cellular metabolic process cellular nitrogen compound biosynthetic process cellular nitrogen compound metabolic process cellular process cellular_component cytoplasm cytosol developmental process extracellular exosome extracellular membrane-bounded organelle extracellular organelle extracellular vesicle glutamine family amino acid metabolic process glutamine metabolic process head development heterocycle biosynthetic process heterocycle metabolic process heterocyclic compound binding ion binding ligase activity, forming carbon-nitrogen bonds ligase activity membrane-bounded organelle metabolic process metal ion binding molecular_function nitrogen compound metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoside monophosphate biosynthetic process nucleoside monophosphate metabolic process nucleoside phosphate binding nucleoside phosphate biosynthetic process nucleoside phosphate metabolic process nucleotide binding nucleotide biosynthetic process nucleotide metabolic process organelle organic acid metabolic process organic cyclic compound binding organic cyclic compound biosynthetic process organic cyclic compound metabolic process organic substance biosynthetic process organic substance metabolic process organonitrogen compound biosynthetic process organonitrogen compound metabolic process organophosphate biosynthetic process organophosphate metabolic process oxoacid metabolic process phosphate-containing compound metabolic process phosphoribosylformylglycinamidine synthase activity phosphorus metabolic process primary metabolic process purine nucleoside monophosphate biosynthetic process purine nucleoside monophosphate metabolic process purine nucleotide binding purine nucleotide biosynthetic process purine nucleotide metabolic process purine ribonucleoside monophosphate biosynthetic process purine ribonucleoside monophosphate metabolic process purine ribonucleoside triphosphate binding purine ribonucleotide binding purine ribonucleotide biosynthetic process purine ribonucleotide metabolic process purine-containing compound biosynthetic process purine-containing compound metabolic process response to chemical response to stimulus response to xenobiotic stimulus ribonucleoside monophosphate biosynthetic process ribonucleoside monophosphate metabolic process ribonucleotide binding ribonucleotide biosynthetic process ribonucleotide metabolic process ribose phosphate biosynthetic process ribose phosphate metabolic process small molecule binding small molecule metabolic process vesicle	GO:0000166 GO:0003674 GO:0003824 GO:0004642 GO:0005488 GO:0005524 GO:0005575 GO:0005737 GO:0005829 GO:0006082 GO:0006139 GO:0006163 GO:0006164 GO:0006167 GO:0006177 GO:0006188 GO:0006189 GO:0006520 GO:0006541 GO:0006725 GO:0006753 GO:0006793 GO:0006796 GO:0006807 GO:0008150 GO:0008152 GO:0009058 GO:0009064 GO:0009117 GO:0009123 GO:0009124 GO:0009126 GO:0009127 GO:0009150 GO:0009152 GO:0009156 GO:0009161 GO:0009165 GO:0009167 GO:0009168 GO:0009259 GO:0009260 GO:0009410 GO:0009987 GO:0016874 GO:0016879 GO:0016884 GO:0017076 GO:0018130 GO:0019438 GO:0019637 GO:0019693 GO:0019752 GO:0030554 GO:0031982 GO:0032502 GO:0032553 GO:0032555 GO:0032559 GO:0034641 GO:0034654 GO:0035639 GO:0036094 GO:0042221 GO:0043167 GO:0043168 GO:0043169 GO:0043226 GO:0043227 GO:0043230 GO:0043436 GO:0044208 GO:0044237 GO:0044238 GO:0044249 GO:0044271 GO:0044281 GO:0046033 GO:0046037 GO:0046040 GO:0046390 GO:0046483 GO:0046872 GO:0048856 GO:0050896 GO:0055086 GO:0060322 GO:0065010 GO:0070062 GO:0071704 GO:0072521 GO:0072522 GO:0090407 GO:0097065 GO:0097159 GO:0097292 GO:0097293 GO:0097294 GO:0097367 GO:0110165 GO:1901135 GO:1901137 GO:1901265 GO:1901293 GO:1901360 GO:1901362 GO:1901363 GO:1901564 GO:1901566 GO:1901576 GO:1901605 GO:1903561
471	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	ATIC Aliases: AICARFT IMPCHASE PURH phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Homo sapiens (human)	9606			'de novo' AMP biosynthetic process 'de novo' IMP biosynthetic process 'de novo' XMP biosynthetic process AMP biosynthetic process AMP metabolic process GMP biosynthetic process GMP metabolic process IMP biosynthetic process IMP cyclohydrolase activity IMP metabolic process XMP biosynthetic process XMP metabolic process anatomical structure development animal organ development animal organ regeneration aromatic compound biosynthetic process binding biological_process biosynthetic process brainstem development cadherin binding carbohydrate derivative biosynthetic process carbohydrate derivative metabolic process carboxylic acid metabolic process catalytic activity cell adhesion molecule binding cellular anatomical entity cellular aromatic compound metabolic process cellular biosynthetic process cellular metabolic process cellular modified amino acid biosynthetic process cellular modified amino acid metabolic process cellular nitrogen compound biosynthetic process cellular nitrogen compound metabolic process cellular process cellular response to chemical stimulus cellular response to cytokine stimulus cellular response to interleukin-7 cellular response to organic substance cellular response to stimulus cellular_component cerebellum development cerebral cortex development cyclohydrolase activity cytosol developmental process dicarboxylic acid metabolic process dihydrofolate metabolic process extracellular exosome extracellular membrane-bounded organelle extracellular organelle extracellular vesicle folic acid-containing compound biosynthetic process folic acid-containing compound metabolic process heterocycle biosynthetic process heterocycle metabolic process hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds hydrolase activity hydroxymethyl-, formyl- and related transferase activity identical protein binding membrane-bounded organelle membrane metabolic process molecular_function nitrogen compound metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoside monophosphate biosynthetic process nucleoside monophosphate metabolic process nucleoside phosphate biosynthetic process nucleoside phosphate metabolic process nucleotide biosynthetic process nucleotide metabolic process organelle organic acid metabolic process organic cyclic compound biosynthetic process organic cyclic compound metabolic process organic substance biosynthetic process organic substance metabolic process organonitrogen compound biosynthetic process organonitrogen compound metabolic process organophosphate biosynthetic process organophosphate metabolic process oxoacid metabolic process phosphate-containing compound metabolic process phosphoribosylaminoimidazolecarboxamide formyltransferase activity phosphorus metabolic process plasma membrane primary metabolic process protein binding protein dimerization activity protein homodimerization activity pteridine-containing compound biosynthetic process pteridine-containing compound metabolic process purine nucleoside monophosphate biosynthetic process purine nucleoside monophosphate metabolic process purine nucleotide biosynthetic process purine nucleotide metabolic process purine ribonucleoside monophosphate biosynthetic process purine ribonucleoside monophosphate metabolic process purine ribonucleotide biosynthetic process purine ribonucleotide metabolic process purine-containing compound biosynthetic process purine-containing compound metabolic process regeneration response to chemical response to cytokine response to interleukin-7 response to organic substance response to stimulus ribonucleoside monophosphate biosynthetic process ribonucleoside monophosphate metabolic process ribonucleotide biosynthetic process ribonucleotide metabolic process ribose phosphate biosynthetic process ribose phosphate metabolic process small molecule metabolic process tetrahydrofolate biosynthetic process tetrahydrofolate metabolic process transferase activity, transferring one-carbon groups transferase activity vesicle	GO:0003360 GO:0003674 GO:0003824 GO:0003937 GO:0004643 GO:0005488 GO:0005515 GO:0005575 GO:0005829 GO:0005886 GO:0006082 GO:0006139 GO:0006163 GO:0006164 GO:0006167 GO:0006177 GO:0006188 GO:0006189 GO:0006575 GO:0006725 GO:0006753 GO:0006760 GO:0006793 GO:0006796 GO:0006807 GO:0008150 GO:0008152 GO:0009058 GO:0009117 GO:0009123 GO:0009124 GO:0009126 GO:0009127 GO:0009150 GO:0009152 GO:0009156 GO:0009161 GO:0009165 GO:0009167 GO:0009168 GO:0009259 GO:0009260 GO:0009396 GO:0009987 GO:0010033 GO:0016020 GO:0016740 GO:0016741 GO:0016742 GO:0016787 GO:0016810 GO:0016814 GO:0018130 GO:0019238 GO:0019438 GO:0019637 GO:0019693 GO:0019752 GO:0021549 GO:0021987 GO:0031099 GO:0031100 GO:0031982 GO:0032502 GO:0034097 GO:0034641 GO:0034654 GO:0042221 GO:0042398 GO:0042558 GO:0042559 GO:0042802 GO:0042803 GO:0043226 GO:0043227 GO:0043230 GO:0043436 GO:0043648 GO:0044208 GO:0044237 GO:0044238 GO:0044249 GO:0044271 GO:0044281 GO:0045296 GO:0046033 GO:0046037 GO:0046040 GO:0046390 GO:0046452 GO:0046483 GO:0046653 GO:0046654 GO:0046983 GO:0048513 GO:0048856 GO:0050839 GO:0050896 GO:0051716 GO:0055086 GO:0065010 GO:0070062 GO:0070887 GO:0071310 GO:0071345 GO:0071704 GO:0072521 GO:0072522 GO:0090407 GO:0097292 GO:0097293 GO:0097294 GO:0098760 GO:0098761 GO:0110165 GO:1901135 GO:1901137 GO:1901293 GO:1901360 GO:1901362 GO:1901564 GO:1901566 GO:1901576 GO:1903561
159	adenylosuccinate synthase 2	ADSS2	Homo sapiens (human)	9606			'de novo' AMP biosynthetic process AMP biosynthetic process AMP metabolic process GTP binding IMP metabolic process adenylosuccinate synthase activity alpha-amino acid metabolic process amino acid metabolic process anion binding aromatic compound biosynthetic process aspartate family amino acid metabolic process aspartate metabolic process binding biological_process biosynthetic process carbohydrate derivative binding carbohydrate derivative biosynthetic process carbohydrate derivative metabolic process carboxylic acid metabolic process catalytic activity cation binding cellular anatomical entity cellular aromatic compound metabolic process cellular biosynthetic process cellular metabolic process cellular nitrogen compound biosynthetic process cellular nitrogen compound metabolic process cellular process cellular response to abiotic stimulus cellular response to electrical stimulus cellular response to environmental stimulus cellular response to stimulus cellular_component cytoplasm cytosol dicarboxylic acid metabolic process extracellular exosome extracellular membrane-bounded organelle extracellular organelle extracellular vesicle guanyl nucleotide binding guanyl ribonucleotide binding heterocycle biosynthetic process heterocycle metabolic process heterocyclic compound binding immune system process intracellular membrane-bounded organelle intracellular organelle ion binding ligase activity, forming carbon-nitrogen bonds ligase activity magnesium ion binding membrane-bounded organelle metabolic process metal ion binding mitochondrion molecular_function nitrogen compound metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoside monophosphate biosynthetic process nucleoside monophosphate metabolic process nucleoside phosphate binding nucleoside phosphate biosynthetic process nucleoside phosphate metabolic process nucleotide binding nucleotide biosynthetic process nucleotide metabolic process organelle organic acid metabolic process organic cyclic compound binding organic cyclic compound biosynthetic process organic cyclic compound metabolic process organic substance biosynthetic process organic substance metabolic process organonitrogen compound biosynthetic process organonitrogen compound metabolic process organophosphate biosynthetic process organophosphate metabolic process oxoacid metabolic process phosphate ion binding phosphate-containing compound metabolic process phosphorus metabolic process primary metabolic process protein binding purine nucleoside monophosphate biosynthetic process purine nucleoside monophosphate metabolic process purine nucleotide binding purine nucleotide biosynthetic process purine nucleotide metabolic process purine ribonucleoside monophosphate biosynthetic process purine ribonucleoside monophosphate metabolic process purine ribonucleoside triphosphate binding purine ribonucleotide binding purine ribonucleotide biosynthetic process purine ribonucleotide metabolic process purine-containing compound biosynthetic process purine-containing compound metabolic process response to abiotic stimulus response to ammonium ion response to chemical response to electrical stimulus response to inorganic substance response to nitrogen compound response to organic cyclic compound response to organic substance response to organonitrogen compound response to purine-containing compound response to stimulus ribonucleoside monophosphate biosynthetic process ribonucleoside monophosphate metabolic process ribonucleotide binding ribonucleotide biosynthetic process ribonucleotide metabolic process ribose phosphate biosynthetic process ribose phosphate metabolic process small molecule binding small molecule metabolic process vesicle	GO:0000166 GO:0000287 GO:0002376 GO:0003674 GO:0003824 GO:0004019 GO:0005488 GO:0005515 GO:0005525 GO:0005575 GO:0005737 GO:0005739 GO:0005829 GO:0006082 GO:0006139 GO:0006163 GO:0006164 GO:0006167 GO:0006520 GO:0006531 GO:0006725 GO:0006753 GO:0006793 GO:0006796 GO:0006807 GO:0008150 GO:0008152 GO:0009058 GO:0009066 GO:0009117 GO:0009123 GO:0009124 GO:0009126 GO:0009127 GO:0009150 GO:0009152 GO:0009156 GO:0009161 GO:0009165 GO:0009167 GO:0009168 GO:0009259 GO:0009260 GO:0009628 GO:0009987 GO:0010033 GO:0010035 GO:0010243 GO:0014070 GO:0014074 GO:0016874 GO:0016879 GO:0017076 GO:0018130 GO:0019001 GO:0019438 GO:0019637 GO:0019693 GO:0019752 GO:0031982 GO:0032553 GO:0032555 GO:0032561 GO:0034641 GO:0034654 GO:0035639 GO:0036094 GO:0042221 GO:0042301 GO:0043167 GO:0043168 GO:0043169 GO:0043226 GO:0043227 GO:0043229 GO:0043230 GO:0043231 GO:0043436 GO:0043648 GO:0044208 GO:0044237 GO:0044238 GO:0044249 GO:0044271 GO:0044281 GO:0046033 GO:0046040 GO:0046390 GO:0046483 GO:0046872 GO:0050896 GO:0051602 GO:0051716 GO:0055086 GO:0060359 GO:0065010 GO:0070062 GO:0071214 GO:0071257 GO:0071704 GO:0072521 GO:0072522 GO:0090407 GO:0097159 GO:0097367 GO:0104004 GO:0110165 GO:1901135 GO:1901137 GO:1901265 GO:1901293 GO:1901360 GO:1901362 GO:1901363 GO:1901564 GO:1901566 GO:1901576 GO:1901605 GO:1901698 GO:1903561
1503	CTP synthase 1	CTPS1	Homo sapiens (human)	9606			'de novo' CTP biosynthetic process ATP binding B cell activation B cell proliferation CTP biosynthetic process CTP metabolic process CTP synthase activity T cell activation T cell proliferation adenyl nucleotide binding adenyl ribonucleotide binding alpha-amino acid metabolic process amino acid metabolic process anion binding aromatic compound biosynthetic process binding biological_process biosynthetic process carbohydrate derivative binding carbohydrate derivative biosynthetic process carbohydrate derivative metabolic process carboxylic acid metabolic process catalytic activity cell activation cell population proliferation cellular anatomical entity cellular aromatic compound metabolic process cellular biosynthetic process cellular metabolic process cellular nitrogen compound biosynthetic process cellular nitrogen compound metabolic process cellular process cellular_component cytoophidium cytoplasm cytosol glutamine family amino acid metabolic process glutamine metabolic process heterocycle biosynthetic process heterocycle metabolic process heterocyclic compound binding identical protein binding immune system process ion binding leukocyte activation leukocyte proliferation ligase activity, forming carbon-nitrogen bonds ligase activity lymphocyte activation lymphocyte proliferation membrane metabolic process molecular_function mononuclear cell proliferation multicellular organismal process nitrogen compound metabolic process nucleobase biosynthetic process nucleobase metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoside phosphate binding nucleoside phosphate biosynthetic process nucleoside phosphate metabolic process nucleoside triphosphate biosynthetic process nucleoside triphosphate metabolic process nucleotide binding nucleotide biosynthetic process nucleotide metabolic process organic acid metabolic process organic cyclic compound binding organic cyclic compound biosynthetic process organic cyclic compound metabolic process organic substance biosynthetic process organic substance metabolic process organonitrogen compound biosynthetic process organonitrogen compound metabolic process organophosphate biosynthetic process organophosphate metabolic process oxoacid metabolic process phosphate-containing compound metabolic process phosphorus metabolic process primary metabolic process protein binding purine nucleotide binding purine ribonucleoside triphosphate binding purine ribonucleotide binding pyrimidine nucleobase biosynthetic process pyrimidine nucleobase metabolic process pyrimidine nucleoside triphosphate biosynthetic process pyrimidine nucleoside triphosphate metabolic process pyrimidine nucleotide biosynthetic process pyrimidine nucleotide metabolic process pyrimidine ribonucleoside triphosphate biosynthetic process pyrimidine ribonucleoside triphosphate metabolic process pyrimidine ribonucleotide biosynthetic process pyrimidine ribonucleotide metabolic process pyrimidine-containing compound biosynthetic process pyrimidine-containing compound metabolic process response to chemical response to stimulus response to xenobiotic stimulus ribonucleoside triphosphate biosynthetic process ribonucleoside triphosphate metabolic process ribonucleotide binding ribonucleotide biosynthetic process ribonucleotide metabolic process ribose phosphate biosynthetic process ribose phosphate metabolic process small molecule binding small molecule metabolic process supramolecular complex supramolecular fiber supramolecular polymer	GO:0000166 GO:0001775 GO:0002376 GO:0003674 GO:0003824 GO:0003883 GO:0005488 GO:0005515 GO:0005524 GO:0005575 GO:0005737 GO:0005829 GO:0006082 GO:0006139 GO:0006206 GO:0006220 GO:0006221 GO:0006241 GO:0006520 GO:0006541 GO:0006725 GO:0006753 GO:0006793 GO:0006796 GO:0006807 GO:0008150 GO:0008152 GO:0008283 GO:0009058 GO:0009064 GO:0009112 GO:0009117 GO:0009141 GO:0009142 GO:0009147 GO:0009148 GO:0009165 GO:0009199 GO:0009201 GO:0009208 GO:0009209 GO:0009218 GO:0009220 GO:0009259 GO:0009260 GO:0009410 GO:0009987 GO:0016020 GO:0016874 GO:0016879 GO:0017076 GO:0018130 GO:0019438 GO:0019637 GO:0019693 GO:0019752 GO:0019856 GO:0030554 GO:0032501 GO:0032553 GO:0032555 GO:0032559 GO:0032943 GO:0034641 GO:0034654 GO:0035639 GO:0036094 GO:0042098 GO:0042100 GO:0042110 GO:0042113 GO:0042221 GO:0042802 GO:0043167 GO:0043168 GO:0043436 GO:0044210 GO:0044237 GO:0044238 GO:0044249 GO:0044271 GO:0044281 GO:0045321 GO:0046036 GO:0046112 GO:0046390 GO:0046483 GO:0046649 GO:0046651 GO:0050896 GO:0055086 GO:0070661 GO:0071704 GO:0072527 GO:0072528 GO:0090407 GO:0097159 GO:0097268 GO:0097367 GO:0099080 GO:0099081 GO:0099512 GO:0110165 GO:1901135 GO:1901137 GO:1901265 GO:1901293 GO:1901360 GO:1901362 GO:1901363 GO:1901564 GO:1901566 GO:1901576 GO:1901605
2762	GDP-mannose 4,6-dehydratase	GMDS Aliases: GMD SDR3E1 short chain dehydrogenase/reductase family 3E, member 1	Homo sapiens (human)	9606	agnosia arthritis arthropathy autistic disorder cancer cerebral palsy colon cancer colon carcinoma colonic benign neoplasm colorectal cancer colorectal carcinoma congenital disorder of glycosylation type IIc embryoma hemiplegia hepatocellular carcinoma large intestine cancer liver cancer lung adenocarcinoma lung cancer open-angle glaucoma osteoarthritis primary open angle glaucoma spastic diplegia spastic monoplegia spastic quadriplegic cerebral palsy	DOID:0070255 DOID:0080199 DOID:1067 DOID:1070 DOID:10965 DOID:10968 DOID:10969 DOID:10970 DOID:12849 DOID:1324 DOID:1520 DOID:162 DOID:1969 DOID:219 DOID:235 DOID:3571 DOID:381 DOID:3910 DOID:4090 DOID:4766 DOID:5672 DOID:684 DOID:8398 DOID:848 DOID:9256	'de novo' GDP-L-fucose biosynthetic process GDP-L-fucose biosynthetic process GDP-L-fucose metabolic process GDP-mannose 4,6-dehydratase activity GDP-mannose metabolic process NADP binding NADP+ binding Notch signaling pathway adenyl nucleotide binding anion binding aromatic compound biosynthetic process binding biological regulation biological_process biosynthetic process carbohydrate derivative biosynthetic process carbohydrate derivative metabolic process carbon-oxygen lyase activity catalytic activity cell surface receptor signaling pathway cellular anatomical entity cellular aromatic compound metabolic process cellular biosynthetic process cellular metabolic process cellular nitrogen compound biosynthetic process cellular nitrogen compound metabolic process cellular process cellular_component cytoplasm cytosol extracellular exosome extracellular membrane-bounded organelle extracellular organelle extracellular vesicle heterocycle biosynthetic process heterocycle metabolic process heterocyclic compound binding hydro-lyase activity identical protein binding ion binding lyase activity membrane-bounded organelle metabolic process molecular_function nitrogen compound metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoside phosphate binding nucleotide binding nucleotide-sugar biosynthetic process nucleotide-sugar metabolic process organelle organic cyclic compound binding organic cyclic compound biosynthetic process organic cyclic compound metabolic process organic substance biosynthetic process organic substance metabolic process phosphorus metabolic process primary metabolic process protein binding purine nucleotide binding regulation of biological process regulation of cellular process signal transduction small molecule binding small molecule metabolic process vesicle	GO:0000166 GO:0003674 GO:0003824 GO:0005488 GO:0005515 GO:0005575 GO:0005737 GO:0005829 GO:0006139 GO:0006725 GO:0006793 GO:0006807 GO:0007165 GO:0007166 GO:0007219 GO:0008150 GO:0008152 GO:0008446 GO:0009058 GO:0009225 GO:0009226 GO:0009987 GO:0016829 GO:0016835 GO:0016836 GO:0017076 GO:0018130 GO:0019438 GO:0019673 GO:0030554 GO:0031982 GO:0034641 GO:0034654 GO:0036094 GO:0042350 GO:0042351 GO:0042802 GO:0043167 GO:0043168 GO:0043226 GO:0043227 GO:0043230 GO:0044237 GO:0044238 GO:0044249 GO:0044271 GO:0044281 GO:0046368 GO:0046483 GO:0050661 GO:0050789 GO:0050794 GO:0055086 GO:0065007 GO:0065010 GO:0070062 GO:0070401 GO:0071704 GO:0097159 GO:0110165 GO:1901135 GO:1901137 GO:1901265 GO:1901360 GO:1901362 GO:1901363 GO:1901576 GO:1903561
8564	kynurenine 3-monooxygenase	KMO	Homo sapiens (human)	9606			'de novo' NAD biosynthetic process from tryptophan 'de novo' NAD biosynthetic process FAD binding L-kynurenine metabolic process NAD biosynthetic process NAD metabolic process NAD(P)H oxidase H2O2-forming activity alpha-amino acid catabolic process alpha-amino acid metabolic process amine metabolic process amino acid catabolic process amino acid metabolic process anion binding anthranilate metabolic process aromatic amino acid family catabolic process aromatic amino acid metabolic process aromatic compound biosynthetic process aromatic compound catabolic process benzene-containing compound metabolic process binding biogenic amine metabolic process biological regulation biological_process biosynthetic process bounding membrane of organelle carboxylic acid biosynthetic process carboxylic acid catabolic process carboxylic acid metabolic process catabolic process catalytic activity cellular anatomical entity cellular aromatic compound metabolic process cellular biosynthetic process cellular catabolic process cellular ketone metabolic process cellular metabolic process cellular nitrogen compound biosynthetic process cellular nitrogen compound catabolic process cellular nitrogen compound metabolic process cellular process cellular response to biotic stimulus cellular response to chemical stimulus cellular response to cytokine stimulus cellular response to interleukin-1 cellular response to lipid cellular response to lipopolysaccharide cellular response to molecule of bacterial origin cellular response to organic substance cellular response to oxygen-containing compound cellular response to stimulus cellular_component cytosol dicarboxylic acid biosynthetic process dicarboxylic acid metabolic process extracellular space flavin adenine dinucleotide binding heterocycle biosynthetic process heterocycle catabolic process heterocycle metabolic process heterocyclic compound binding indolalkylamine metabolic process indole-containing compound catabolic process indole-containing compound metabolic process intracellular membrane-bounded organelle intracellular organelle ion binding kynurenic acid biosynthetic process kynurenic acid metabolic process kynurenine 3-monooxygenase activity kynurenine metabolic process membrane-bounded organelle membrane metabolic process mitochondrial membrane mitochondrial outer membrane mitochondrion modulation of chemical synaptic transmission molecular_function monocarboxylic acid biosynthetic process monocarboxylic acid metabolic process monooxygenase activity nicotinamide nucleotide biosynthetic process nicotinamide nucleotide metabolic process nitrogen compound metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoside phosphate binding nucleoside phosphate biosynthetic process nucleoside phosphate metabolic process nucleotide binding nucleotide biosynthetic process nucleotide metabolic process organelle membrane organelle outer membrane organelle organic acid biosynthetic process organic acid catabolic process organic acid metabolic process organic cyclic compound binding organic cyclic compound biosynthetic process organic cyclic compound catabolic process organic cyclic compound metabolic process organic substance biosynthetic process organic substance catabolic process organic substance metabolic process organonitrogen compound biosynthetic process organonitrogen compound catabolic process organonitrogen compound metabolic process organophosphate biosynthetic process organophosphate metabolic process outer membrane oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor oxidoreductase activity, acting on NAD(P)H oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen oxidoreductase activity oxoacid metabolic process phosphate-containing compound metabolic process phosphorus metabolic process positive regulation of amine transport positive regulation of amino acid transport positive regulation of biological process positive regulation of cell communication positive regulation of cellular process positive regulation of glutamate secretion, neurotransmission positive regulation of glutamate secretion positive regulation of neurotransmitter secretion positive regulation of neurotransmitter transport positive regulation of organic acid transport positive regulation of secretion by cell positive regulation of secretion positive regulation of signaling positive regulation of synaptic transmission, glutamatergic positive regulation of synaptic transmission positive regulation of transport primary metabolic process protein binding purine nucleotide biosynthetic process purine nucleotide metabolic process purine-containing compound biosynthetic process purine-containing compound metabolic process pyridine nucleotide biosynthetic process pyridine nucleotide metabolic process pyridine-containing compound biosynthetic process pyridine-containing compound metabolic process quinolinate biosynthetic process quinolinate metabolic process regulation of amine transport regulation of amino acid transport regulation of biological process regulation of cell communication regulation of cellular process regulation of glutamate secretion, neurotransmission regulation of glutamate secretion regulation of localization regulation of neurotransmitter secretion regulation of neurotransmitter transport regulation of organic acid transport regulation of secretion by cell regulation of secretion regulation of signaling regulation of synaptic transmission, glutamatergic regulation of trans-synaptic signaling regulation of transport response to abiotic stimulus response to biotic stimulus response to chemical response to cytokine response to external biotic stimulus response to external stimulus response to interleukin-1 response to lipid response to lipopolysaccharide response to molecule of bacterial origin response to organic substance response to osmotic stress response to oxygen-containing compound response to salt stress response to stimulus response to stress small molecule binding small molecule biosynthetic process small molecule catabolic process small molecule metabolic process tryptophan catabolic process tryptophan metabolic process	GO:0000166 GO:0001956 GO:0002237 GO:0003674 GO:0003824 GO:0004497 GO:0004502 GO:0005488 GO:0005515 GO:0005575 GO:0005615 GO:0005739 GO:0005741 GO:0005829 GO:0006082 GO:0006139 GO:0006163 GO:0006164 GO:0006520 GO:0006568 GO:0006569 GO:0006576 GO:0006586 GO:0006725 GO:0006753 GO:0006793 GO:0006796 GO:0006807 GO:0006950 GO:0006970 GO:0008150 GO:0008152 GO:0009056 GO:0009058 GO:0009063 GO:0009072 GO:0009074 GO:0009117 GO:0009165 GO:0009308 GO:0009435 GO:0009605 GO:0009607 GO:0009628 GO:0009651 GO:0009987 GO:0010033 GO:0010646 GO:0010647 GO:0014048 GO:0014049 GO:0016020 GO:0016053 GO:0016054 GO:0016174 GO:0016491 GO:0016651 GO:0016705 GO:0016709 GO:0018130 GO:0019359 GO:0019362 GO:0019363 GO:0019438 GO:0019439 GO:0019637 GO:0019674 GO:0019752 GO:0019805 GO:0019867 GO:0023051 GO:0023056 GO:0031090 GO:0031966 GO:0031968 GO:0032496 GO:0032787 GO:0032879 GO:0032890 GO:0032892 GO:0033993 GO:0034097 GO:0034275 GO:0034276 GO:0034354 GO:0034627 GO:0034641 GO:0034654 GO:0036094 GO:0042180 GO:0042221 GO:0042430 GO:0042436 GO:0042537 GO:0043167 GO:0043168 GO:0043207 GO:0043226 GO:0043227 GO:0043229 GO:0043231 GO:0043420 GO:0043436 GO:0043648 GO:0043650 GO:0044237 GO:0044238 GO:0044248 GO:0044249 GO:0044270 GO:0044271 GO:0044281 GO:0044282 GO:0044283 GO:0046394 GO:0046395 GO:0046483 GO:0046496 GO:0046700 GO:0046874 GO:0046928 GO:0048518 GO:0048522 GO:0050660 GO:0050664 GO:0050789 GO:0050794 GO:0050804 GO:0050806 GO:0050896 GO:0051046 GO:0051047 GO:0051049 GO:0051050 GO:0051588 GO:0051590 GO:0051716 GO:0051952 GO:0051954 GO:0051955 GO:0051957 GO:0051966 GO:0051968 GO:0055086 GO:0065007 GO:0070189 GO:0070555 GO:0070887 GO:0071216 GO:0071219 GO:0071222 GO:0071310 GO:0071345 GO:0071347 GO:0071396 GO:0071704 GO:0071949 GO:0072330 GO:0072521 GO:0072522 GO:0072524 GO:0072525 GO:0090407 GO:0097052 GO:0097159 GO:0098588 GO:0099177 GO:0110165 GO:1901265 GO:1901293 GO:1901360 GO:1901361 GO:1901362 GO:1901363 GO:1901564 GO:1901565 GO:1901566 GO:1901575 GO:1901576 GO:1901605 GO:1901606 GO:1901700 GO:1901701 GO:1903294 GO:1903296 GO:1903530 GO:1903532
125061	arylformamidase	AFMID Aliases: DKFZp686F03259 KF kynurenine formamidase	Homo sapiens (human)	9606	colon cancer colonic benign neoplasm colorectal cancer large intestine cancer	DOID:219 DOID:235 DOID:5672 DOID:9256	'de novo' NAD biosynthetic process from tryptophan 'de novo' NAD biosynthetic process NAD biosynthetic process NAD metabolic process alpha-amino acid catabolic process alpha-amino acid metabolic process amine metabolic process amino acid catabolic process amino acid metabolic process aromatic amino acid family catabolic process aromatic amino acid metabolic process aromatic compound biosynthetic process aromatic compound catabolic process arylformamidase activity benzene-containing compound metabolic process binding biogenic amine metabolic process biological_process biosynthetic process carboxylic acid catabolic process carboxylic acid metabolic process catabolic process catalytic activity cellular anatomical entity cellular aromatic compound metabolic process cellular biosynthetic process cellular catabolic process cellular ketone metabolic process cellular metabolic process cellular nitrogen compound biosynthetic process cellular nitrogen compound catabolic process cellular nitrogen compound metabolic process cellular process cellular_component cytoplasm cytosol heterocycle biosynthetic process heterocycle catabolic process heterocycle metabolic process hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds hydrolase activity indolalkylamine metabolic process indole-containing compound catabolic process indole-containing compound metabolic process intracellular membrane-bounded organelle intracellular organelle kynurenine metabolic process membrane-bounded organelle metabolic process molecular_function nicotinamide nucleotide biosynthetic process nicotinamide nucleotide metabolic process nitrogen compound metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoside phosphate biosynthetic process nucleoside phosphate metabolic process nucleotide biosynthetic process nucleotide metabolic process nucleus organelle organic acid catabolic process organic acid metabolic process organic cyclic compound biosynthetic process organic cyclic compound catabolic process organic cyclic compound metabolic process organic substance biosynthetic process organic substance catabolic process organic substance metabolic process organonitrogen compound biosynthetic process organonitrogen compound catabolic process organonitrogen compound metabolic process organophosphate biosynthetic process organophosphate metabolic process oxoacid metabolic process phosphate-containing compound metabolic process phosphorus metabolic process primary metabolic process protein binding purine nucleotide biosynthetic process purine nucleotide metabolic process purine-containing compound biosynthetic process purine-containing compound metabolic process pyridine nucleotide biosynthetic process pyridine nucleotide metabolic process pyridine-containing compound biosynthetic process pyridine-containing compound metabolic process small molecule catabolic process small molecule metabolic process tryptophan catabolic process to kynurenine tryptophan catabolic process tryptophan metabolic process	GO:0003674 GO:0003824 GO:0004061 GO:0005488 GO:0005515 GO:0005575 GO:0005634 GO:0005737 GO:0005829 GO:0006082 GO:0006139 GO:0006163 GO:0006164 GO:0006520 GO:0006568 GO:0006569 GO:0006576 GO:0006586 GO:0006725 GO:0006753 GO:0006793 GO:0006796 GO:0006807 GO:0008150 GO:0008152 GO:0009056 GO:0009058 GO:0009063 GO:0009072 GO:0009074 GO:0009117 GO:0009165 GO:0009308 GO:0009435 GO:0009987 GO:0016054 GO:0016787 GO:0016810 GO:0016811 GO:0018130 GO:0019359 GO:0019362 GO:0019363 GO:0019438 GO:0019439 GO:0019441 GO:0019637 GO:0019674 GO:0019752 GO:0034354 GO:0034627 GO:0034641 GO:0034654 GO:0042180 GO:0042430 GO:0042436 GO:0042537 GO:0043226 GO:0043227 GO:0043229 GO:0043231 GO:0043436 GO:0044237 GO:0044238 GO:0044248 GO:0044249 GO:0044270 GO:0044271 GO:0044281 GO:0044282 GO:0046395 GO:0046483 GO:0046496 GO:0046700 GO:0055086 GO:0070189 GO:0071704 GO:0072521 GO:0072522 GO:0072524 GO:0072525 GO:0090407 GO:0110165 GO:1901293 GO:1901360 GO:1901361 GO:1901362 GO:1901564 GO:1901565 GO:1901566 GO:1901575 GO:1901576 GO:1901605 GO:1901606
55191	NAD synthetase 1	NADSYN1	Homo sapiens (human)	9606			'de novo' NAD biosynthetic process ATP binding NAD biosynthetic process NAD metabolic process NAD+ synthase (glutamine-hydrolyzing) activity adenyl nucleotide binding adenyl ribonucleotide binding anion binding aromatic compound biosynthetic process binding biological_process biosynthetic process carbohydrate derivative binding carbon-nitrogen ligase activity, with glutamine as amido-N-donor catalytic activity cellular anatomical entity cellular aromatic compound metabolic process cellular biosynthetic process cellular metabolic process cellular nitrogen compound biosynthetic process cellular nitrogen compound metabolic process cellular process cellular_component cytoplasm cytosol glutaminase activity heterocycle biosynthetic process heterocycle metabolic process heterocyclic compound binding hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds hydrolase activity ion binding ligase activity, forming carbon-nitrogen bonds ligase activity metabolic process molecular_function nicotinamide nucleotide biosynthetic process nicotinamide nucleotide metabolic process nitrogen compound metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoside phosphate binding nucleoside phosphate biosynthetic process nucleoside phosphate metabolic process nucleotide binding nucleotide biosynthetic process nucleotide metabolic process organic cyclic compound binding organic cyclic compound biosynthetic process organic cyclic compound metabolic process organic substance biosynthetic process organic substance metabolic process organonitrogen compound biosynthetic process organonitrogen compound metabolic process organophosphate biosynthetic process organophosphate metabolic process phosphate-containing compound metabolic process phosphorus metabolic process primary metabolic process protein binding purine nucleotide binding purine nucleotide biosynthetic process purine nucleotide metabolic process purine ribonucleoside triphosphate binding purine ribonucleotide binding purine-containing compound biosynthetic process purine-containing compound metabolic process pyridine nucleotide biosynthetic process pyridine nucleotide metabolic process pyridine-containing compound biosynthetic process pyridine-containing compound metabolic process ribonucleotide binding small molecule binding small molecule metabolic process	GO:0000166 GO:0003674 GO:0003824 GO:0003952 GO:0004359 GO:0005488 GO:0005515 GO:0005524 GO:0005575 GO:0005737 GO:0005829 GO:0006139 GO:0006163 GO:0006164 GO:0006725 GO:0006753 GO:0006793 GO:0006796 GO:0006807 GO:0008150 GO:0008152 GO:0009058 GO:0009117 GO:0009165 GO:0009435 GO:0009987 GO:0016787 GO:0016810 GO:0016811 GO:0016874 GO:0016879 GO:0016884 GO:0017076 GO:0018130 GO:0019359 GO:0019362 GO:0019363 GO:0019438 GO:0019637 GO:0019674 GO:0030554 GO:0032553 GO:0032555 GO:0032559 GO:0034627 GO:0034641 GO:0034654 GO:0035639 GO:0036094 GO:0043167 GO:0043168 GO:0044237 GO:0044238 GO:0044249 GO:0044271 GO:0044281 GO:0046483 GO:0046496 GO:0055086 GO:0071704 GO:0072521 GO:0072522 GO:0072524 GO:0072525 GO:0090407 GO:0097159 GO:0097367 GO:0110165 GO:1901265 GO:1901293 GO:1901360 GO:1901362 GO:1901363 GO:1901564 GO:1901566 GO:1901576
790	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	CAD Aliases: GATD4	Homo sapiens (human)	9606			'de novo' UMP biosynthetic process 'de novo' pyrimidine nucleobase biosynthetic process ATP binding UDP biosynthetic process UDP metabolic process UMP biosynthetic process UMP metabolic process UTP biosynthetic process UTP metabolic process adenyl nucleotide binding adenyl ribonucleotide binding alpha-amino acid biosynthetic process alpha-amino acid metabolic process amino acid binding amino acid biosynthetic process amino acid metabolic process anatomical structure development animal organ development animal organ regeneration anion binding aromatic compound biosynthetic process aspartate binding aspartate carbamoyltransferase activity binding biological regulation biological_process biosynthetic process body fluid secretion carbamoyl-phosphate synthase (ammonia) activity carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity carbohydrate derivative binding carbohydrate derivative biosynthetic process carbohydrate derivative metabolic process carbon-nitrogen ligase activity, with glutamine as amido-N-donor carboxyl- or carbamoyltransferase activity carboxylic acid binding carboxylic acid biosynthetic process carboxylic acid metabolic process catalytic activity, acting on a protein catalytic activity cation binding cell body cell projection cellular anatomical entity cellular aromatic compound metabolic process cellular biosynthetic process cellular metabolic process cellular nitrogen compound biosynthetic process cellular nitrogen compound metabolic process cellular process cellular response to endogenous stimulus cellular response to epidermal growth factor stimulus cellular response to growth factor stimulus cellular_component citrulline biosynthetic process citrulline metabolic process cytoplasm cytosol developmental process dihydroorotase activity enzyme binding establishment of localization extracellular exosome extracellular membrane-bounded organelle extracellular organelle extracellular vesicle female pregnancy gland development glutaminase activity glutamine family amino acid metabolic process glutamine metabolic process heart development heterocycle biosynthetic process heterocycle metabolic process heterocyclic compound binding hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds hydrolase activity identical protein binding intracellular membrane-bounded organelle intracellular organelle ion binding kinase activity lactation ligase activity, forming carbon-nitrogen bonds ligase activity liver development localization macromolecule metabolic process macromolecule modification membrane-bounded organelle membrane metabolic process metal ion binding molecular_function multi-multicellular organism process multi-organism reproductive process multicellular organismal process neuronal cell body nitrogen compound metabolic process nuclear matrix nucleobase biosynthetic process nucleobase metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoside diphosphate biosynthetic process nucleoside diphosphate metabolic process nucleoside monophosphate biosynthetic process nucleoside monophosphate metabolic process nucleoside phosphate binding nucleoside phosphate biosynthetic process nucleoside phosphate metabolic process nucleoside triphosphate biosynthetic process nucleoside triphosphate metabolic process nucleotide binding nucleotide biosynthetic process nucleotide metabolic process nucleus organelle organic acid binding organic acid biosynthetic process organic acid metabolic process organic cyclic compound binding organic cyclic compound biosynthetic process organic cyclic compound metabolic process organic substance biosynthetic process organic substance metabolic process organonitrogen compound biosynthetic process organonitrogen compound metabolic process organophosphate biosynthetic process organophosphate metabolic process oxoacid metabolic process peptidyl-amino acid modification peptidyl-threonine modification peptidyl-threonine phosphorylation phosphate-containing compound metabolic process phosphorus metabolic process phosphorylation phosphotransferase activity, alcohol group as acceptor presynapse primary metabolic process protein autophosphorylation protein binding protein kinase activity protein metabolic process protein modification process protein phosphorylation protein-containing complex purine nucleotide binding purine ribonucleoside triphosphate binding purine ribonucleotide binding pyrimidine nucleobase biosynthetic process pyrimidine nucleobase metabolic process pyrimidine nucleoside diphosphate biosynthetic process pyrimidine nucleoside diphosphate metabolic process pyrimidine nucleoside monophosphate biosynthetic process pyrimidine nucleoside monophosphate metabolic process pyrimidine nucleoside triphosphate biosynthetic process pyrimidine nucleoside triphosphate metabolic process pyrimidine nucleotide biosynthetic process pyrimidine nucleotide metabolic process pyrimidine ribonucleoside diphosphate biosynthetic process pyrimidine ribonucleoside diphosphate metabolic process pyrimidine ribonucleoside monophosphate biosynthetic process pyrimidine ribonucleoside monophosphate metabolic process pyrimidine ribonucleoside triphosphate biosynthetic process pyrimidine ribonucleoside triphosphate metabolic process pyrimidine ribonucleotide biosynthetic process pyrimidine ribonucleotide metabolic process pyrimidine-containing compound biosynthetic process pyrimidine-containing compound metabolic process regeneration regulation of biological quality regulation of body fluid levels reproductive process response to alcohol response to alkaloid response to amine response to caffeine response to chemical response to corticosteroid response to cortisol response to endogenous stimulus response to epidermal growth factor response to external stimulus response to extracellular stimulus response to glucocorticoid response to growth factor response to hormone response to insulin response to ketone response to lipid response to nitrogen compound response to nutrient levels response to organic cyclic compound response to organic substance response to organonitrogen compound response to oxygen-containing compound response to peptide hormone response to peptide response to purine-containing compound response to starvation response to steroid hormone response to stimulus response to stress response to testosterone ribonucleoside diphosphate biosynthetic process ribonucleoside diphosphate metabolic process ribonucleoside monophosphate biosynthetic process ribonucleoside monophosphate metabolic process ribonucleoside triphosphate biosynthetic process ribonucleoside triphosphate metabolic process ribonucleotide binding ribonucleotide biosynthetic process ribonucleotide metabolic process ribose phosphate biosynthetic process ribose phosphate metabolic process secretion small molecule binding small molecule biosynthetic process small molecule metabolic process terminal bouton transferase activity, transferring one-carbon groups transferase activity, transferring phosphorus-containing groups transferase activity transition metal ion binding transport vesicle xenobiotic metabolic process zinc ion binding	GO:0000052 GO:0000166 GO:0001889 GO:0003674 GO:0003824 GO:0004070 GO:0004087 GO:0004088 GO:0004151 GO:0004359 GO:0004672 GO:0005488 GO:0005515 GO:0005524 GO:0005575 GO:0005634 GO:0005737 GO:0005829 GO:0006082 GO:0006139 GO:0006206 GO:0006207 GO:0006220 GO:0006221 GO:0006222 GO:0006225 GO:0006228 GO:0006468 GO:0006520 GO:0006541 GO:0006725 GO:0006753 GO:0006793 GO:0006796 GO:0006805 GO:0006807 GO:0006810 GO:0006950 GO:0007507 GO:0007565 GO:0007589 GO:0007595 GO:0008150 GO:0008152 GO:0008270 GO:0008652 GO:0009058 GO:0009064 GO:0009112 GO:0009117 GO:0009123 GO:0009124 GO:0009129 GO:0009130 GO:0009132 GO:0009133 GO:0009138 GO:0009139 GO:0009141 GO:0009142 GO:0009147 GO:0009148 GO:0009156 GO:0009161 GO:0009165 GO:0009173 GO:0009174 GO:0009185 GO:0009188 GO:0009193 GO:0009194 GO:0009199 GO:0009201 GO:0009208 GO:0009209 GO:0009218 GO:0009220 GO:0009259 GO:0009260 GO:0009605 GO:0009719 GO:0009725 GO:0009987 GO:0009991 GO:0010033 GO:0010243 GO:0014070 GO:0014074 GO:0014075 GO:0016020 GO:0016053 GO:0016301 GO:0016310 GO:0016363 GO:0016597 GO:0016740 GO:0016741 GO:0016743 GO:0016772 GO:0016773 GO:0016787 GO:0016810 GO:0016811 GO:0016812 GO:0016874 GO:0016879 GO:0016884 GO:0017076 GO:0018107 GO:0018130 GO:0018193 GO:0018210 GO:0019240 GO:0019438 GO:0019538 GO:0019637 GO:0019693 GO:0019752 GO:0019856 GO:0019899 GO:0022414 GO:0030554 GO:0031000 GO:0031099 GO:0031100 GO:0031406 GO:0031667 GO:0031960 GO:0031982 GO:0032501 GO:0032502 GO:0032553 GO:0032555 GO:0032559 GO:0032868 GO:0032991 GO:0033574 GO:0033993 GO:0034641 GO:0034654 GO:0035639 GO:0036094 GO:0036211 GO:0042221 GO:0042594 GO:0042802 GO:0042995 GO:0043025 GO:0043167 GO:0043168 GO:0043169 GO:0043170 GO:0043177 GO:0043195 GO:0043226 GO:0043227 GO:0043229 GO:0043230 GO:0043231 GO:0043279 GO:0043412 GO:0043434 GO:0043436 GO:0044205 GO:0044237 GO:0044238 GO:0044249 GO:0044271 GO:0044281 GO:0044283 GO:0044297 GO:0044703 GO:0044706 GO:0046048 GO:0046049 GO:0046051 GO:0046112 GO:0046390 GO:0046394 GO:0046483 GO:0046777 GO:0046872 GO:0046903 GO:0046914 GO:0048513 GO:0048545 GO:0048732 GO:0048856 GO:0050878 GO:0050896 GO:0051179 GO:0051234 GO:0051384 GO:0051414 GO:0055086 GO:0065007 GO:0065008 GO:0065010 GO:0070062 GO:0070335 GO:0070848 GO:0070849 GO:0071363 GO:0071364 GO:0071495 GO:0071704 GO:0072527 GO:0072528 GO:0090407 GO:0097159 GO:0097305 GO:0097367 GO:0098793 GO:0110165 GO:0140096 GO:1901135 GO:1901137 GO:1901265 GO:1901293 GO:1901360 GO:1901362 GO:1901363 GO:1901564 GO:1901566 GO:1901576 GO:1901605 GO:1901607 GO:1901652 GO:1901654 GO:1901698 GO:1901700 GO:1903561
7372	uridine monophosphate synthetase	UMPS Aliases: orotate phosphoribosyl transferase and orotidine-5'-decarboxylase	Homo sapiens (human)	9606	Diamond-Blackfan anemia Gilbert syndrome agranulocytosis anemia basal cell carcinoma beta thalassemia bile duct adenocarcinoma bile duct carcinoma bilirubin metabolic disorder bladder carcinoma breast cancer breast carcinoma bronchus cancer bronchus carcinoma cancer carbamoyl phosphate synthetase I deficiency disease carcinoma carpal tunnel syndrome cholangiocarcinoma colon cancer colonic benign neoplasm colorectal cancer colorectal carcinoma congenital hypoplastic anemia coronary artery disease diarrhea disease of metabolism embryoma esophageal cancer esophageal carcinoma esophagus squamous cell carcinoma gastrointestinal system cancer gonorrhea hepatocellular carcinoma hereditary spherocytosis intellectual disability intrahepatic cholangiocarcinoma large intestine cancer learning disability leukopenia liver cancer lung benign neoplasm lung cancer lung carcinoma lung non-small cell carcinoma macrocytic anemia malaria megaloblastic anemia neutropenia orotic aciduria pancreatic cancer pancreatic carcinoma patent ductus arteriosus prostate cancer prostate carcinoma prostatic adenoma purine-pyrimidine metabolic disorder rectal benign neoplasm rectum adenocarcinoma rectum cancer sarcomatoid carcinoma sebaceous carcinoma severe congenital neutropenia sickle cell anemia squamous cell carcinoma stomach cancer stomach carcinoma sweat gland cancer thalassemia tongue squamous cell carcinoma tuberculosis urinary bladder cancer	DOID:0014667 DOID:0050590 DOID:0050833 DOID:0050865 DOID:0080199 DOID:10241 DOID:10283 DOID:10286 DOID:10534 DOID:1059 DOID:10923 DOID:11054 DOID:1107 DOID:12169 DOID:12241 DOID:1227 DOID:12365 DOID:12971 DOID:12987 DOID:1324 DOID:1325 DOID:13250 DOID:13382 DOID:1339 DOID:1342 DOID:13832 DOID:1612 DOID:162 DOID:1749 DOID:1793 DOID:1984 DOID:1993 DOID:1996 DOID:2095 DOID:219 DOID:235 DOID:2355 DOID:2361 DOID:2513 DOID:2739 DOID:2741 DOID:2883 DOID:305 DOID:3119 DOID:3393 DOID:3459 DOID:3571 DOID:3683 DOID:3748 DOID:3904 DOID:3905 DOID:3908 DOID:399 DOID:4007 DOID:4015 DOID:4766 DOID:4840 DOID:4896 DOID:4897 DOID:4905 DOID:4928 DOID:4947 DOID:5041 DOID:5517 DOID:5672 DOID:615 DOID:653 DOID:684 DOID:7551 DOID:8927 DOID:9256 DOID:9280	'de novo' UMP biosynthetic process 'de novo' pyrimidine nucleobase biosynthetic process UDP biosynthetic process UDP metabolic process UMP biosynthetic process UMP metabolic process aromatic compound biosynthetic process binding biological regulation biological_process biosynthetic process body fluid secretion carbohydrate derivative biosynthetic process carbohydrate derivative metabolic process carbon-carbon lyase activity carboxy-lyase activity catalytic activity cellular anatomical entity cellular aromatic compound metabolic process cellular biosynthetic process cellular metabolic process cellular nitrogen compound biosynthetic process cellular nitrogen compound metabolic process cellular process cellular response to chemical stimulus cellular response to stimulus cellular response to xenobiotic stimulus cellular_component cytoplasm cytosol establishment of localization female pregnancy glycosyltransferase activity heterocycle biosynthetic process heterocycle metabolic process identical protein binding intracellular membrane-bounded organelle intracellular organelle lactation localization lyase activity membrane-bounded organelle metabolic process molecular_function multi-multicellular organism process multi-organism reproductive process multicellular organismal process nitrogen compound metabolic process nucleobase biosynthetic process nucleobase metabolic process nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoside diphosphate biosynthetic process nucleoside diphosphate metabolic process nucleoside monophosphate biosynthetic process nucleoside monophosphate metabolic process nucleoside phosphate biosynthetic process nucleoside phosphate metabolic process nucleotide biosynthetic process nucleotide metabolic process nucleus organelle organic cyclic compound biosynthetic process organic cyclic compound metabolic process organic substance biosynthetic process organic substance metabolic process organonitrogen compound biosynthetic process organonitrogen compound metabolic process organophosphate biosynthetic process organophosphate metabolic process orotate phosphoribosyltransferase activity orotidine-5'-phosphate decarboxylase activity pentosyltransferase activity phosphate-containing compound metabolic process phosphorus metabolic process primary metabolic process protein binding pyrimidine nucleobase biosynthetic process pyrimidine nucleobase metabolic process pyrimidine nucleoside diphosphate biosynthetic process pyrimidine nucleoside diphosphate metabolic process pyrimidine nucleoside monophosphate biosynthetic process pyrimidine nucleoside monophosphate metabolic process pyrimidine nucleotide biosynthetic process pyrimidine nucleotide metabolic process pyrimidine ribonucleoside diphosphate biosynthetic process pyrimidine ribonucleoside diphosphate metabolic process pyrimidine ribonucleoside monophosphate biosynthetic process pyrimidine ribonucleoside monophosphate metabolic process pyrimidine ribonucleotide biosynthetic process pyrimidine ribonucleotide metabolic process pyrimidine-containing compound biosynthetic process pyrimidine-containing compound metabolic process regulation of biological quality regulation of body fluid levels reproductive process response to chemical response to stimulus response to xenobiotic stimulus ribonucleoside diphosphate biosynthetic process ribonucleoside diphosphate metabolic process ribonucleoside monophosphate biosynthetic process ribonucleoside monophosphate metabolic process ribonucleotide biosynthetic process ribonucleotide metabolic process ribose phosphate biosynthetic process ribose phosphate metabolic process secretion small molecule metabolic process transferase activity transport	GO:0003674 GO:0003824 GO:0004588 GO:0004590 GO:0005488 GO:0005515 GO:0005575 GO:0005634 GO:0005737 GO:0005829 GO:0006139 GO:0006206 GO:0006207 GO:0006220 GO:0006221 GO:0006222 GO:0006225 GO:0006725 GO:0006753 GO:0006793 GO:0006796 GO:0006807 GO:0006810 GO:0007565 GO:0007589 GO:0007595 GO:0008150 GO:0008152 GO:0009058 GO:0009112 GO:0009117 GO:0009123 GO:0009124 GO:0009129 GO:0009130 GO:0009132 GO:0009133 GO:0009138 GO:0009139 GO:0009156 GO:0009161 GO:0009165 GO:0009173 GO:0009174 GO:0009185 GO:0009188 GO:0009193 GO:0009194 GO:0009218 GO:0009220 GO:0009259 GO:0009260 GO:0009410 GO:0009987 GO:0016740 GO:0016757 GO:0016763 GO:0016829 GO:0016830 GO:0016831 GO:0018130 GO:0019438 GO:0019637 GO:0019693 GO:0019856 GO:0022414 GO:0032501 GO:0034641 GO:0034654 GO:0042221 GO:0042802 GO:0043226 GO:0043227 GO:0043229 GO:0043231 GO:0044205 GO:0044237 GO:0044238 GO:0044249 GO:0044271 GO:0044281 GO:0044703 GO:0044706 GO:0046048 GO:0046049 GO:0046112 GO:0046390 GO:0046483 GO:0046903 GO:0050878 GO:0050896 GO:0051179 GO:0051234 GO:0051716 GO:0055086 GO:0065007 GO:0065008 GO:0070887 GO:0071466 GO:0071704 GO:0072527 GO:0072528 GO:0090407 GO:0110165 GO:1901135 GO:1901137 GO:1901293 GO:1901360 GO:1901362 GO:1901564 GO:1901566 GO:1901576
3615	inosine monophosphate dehydrogenase 2	IMPDH2	Homo sapiens (human)	9606			'de novo' XMP biosynthetic process DNA binding GMP biosynthetic process GMP metabolic process GTP biosynthetic process GTP metabolic process IMP dehydrogenase activity RNA binding XMP biosynthetic process XMP metabolic process aromatic compound biosynthetic process binding biological_process biosynthetic process bounding membrane of organelle carbohydrate derivative biosynthetic process carbohydrate derivative metabolic process catalytic activity cation binding cell activation cell population proliferation cellular anatomical entity cellular aromatic compound metabolic process cellular biosynthetic process cellular metabolic process cellular nitrogen compound biosynthetic process cellular nitrogen compound metabolic process cellular process cellular response to chemical stimulus cellular response to cytokine stimulus cellular response to interleukin-4 cellular response to organic substance cellular response to stimulus cellular_component circadian rhythm cytoplasm cytoplasmic vesicle lumen cytosol extracellular exosome extracellular membrane-bounded organelle extracellular organelle extracellular region extracellular vesicle ficolin-1-rich granule lumen heterocycle biosynthetic process heterocycle metabolic process heterocyclic compound binding immune system process intracellular membrane-bounded organelle intracellular organelle lumen intracellular organelle ion binding leukocyte activation leukocyte proliferation lymphocyte activation lymphocyte proliferation membrane-bounded organelle membrane-enclosed lumen membrane metabolic process metal ion binding microbody membrane microbody molecular_function mononuclear cell proliferation multicellular organismal process nitrogen compound metabolic process nucleic acid binding nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoside monophosphate biosynthetic process nucleoside monophosphate metabolic process nucleoside phosphate binding nucleoside phosphate biosynthetic process nucleoside phosphate metabolic process nucleoside triphosphate biosynthetic process nucleoside triphosphate metabolic process nucleotide binding nucleotide biosynthetic process nucleotide metabolic process nucleus organelle lumen organelle membrane organelle organic cyclic compound binding organic cyclic compound biosynthetic process organic cyclic compound metabolic process organic substance biosynthetic process organic substance metabolic process organonitrogen compound biosynthetic process organonitrogen compound metabolic process organophosphate biosynthetic process organophosphate metabolic process oxidoreductase activity, acting on CH-OH group of donors oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor oxidoreductase activity peroxisomal membrane phosphate-containing compound metabolic process phosphorus metabolic process primary metabolic process protein binding purine nucleoside monophosphate biosynthetic process purine nucleoside monophosphate metabolic process purine nucleoside triphosphate biosynthetic process purine nucleoside triphosphate metabolic process purine nucleotide biosynthetic process purine nucleotide metabolic process purine ribonucleoside monophosphate biosynthetic process purine ribonucleoside monophosphate metabolic process purine ribonucleoside triphosphate biosynthetic process purine ribonucleoside triphosphate metabolic process purine ribonucleotide biosynthetic process purine ribonucleotide metabolic process purine-containing compound biosynthetic process purine-containing compound metabolic process response to chemical response to cytokine response to interleukin-4 response to organic substance response to stimulus rhythmic process ribonucleoside monophosphate biosynthetic process ribonucleoside monophosphate metabolic process ribonucleoside triphosphate biosynthetic process ribonucleoside triphosphate metabolic process ribonucleotide biosynthetic process ribonucleotide metabolic process ribose phosphate biosynthetic process ribose phosphate metabolic process secretory granule lumen small molecule binding small molecule metabolic process vesicle lumen vesicle	GO:0000166 GO:0001775 GO:0002376 GO:0003674 GO:0003676 GO:0003677 GO:0003723 GO:0003824 GO:0003938 GO:0005488 GO:0005515 GO:0005575 GO:0005576 GO:0005634 GO:0005737 GO:0005778 GO:0005829 GO:0006139 GO:0006163 GO:0006164 GO:0006177 GO:0006183 GO:0006725 GO:0006753 GO:0006793 GO:0006796 GO:0006807 GO:0007623 GO:0008150 GO:0008152 GO:0008283 GO:0009058 GO:0009117 GO:0009123 GO:0009124 GO:0009126 GO:0009127 GO:0009141 GO:0009142 GO:0009144 GO:0009145 GO:0009150 GO:0009152 GO:0009156 GO:0009161 GO:0009165 GO:0009167 GO:0009168 GO:0009199 GO:0009201 GO:0009205 GO:0009206 GO:0009259 GO:0009260 GO:0009987 GO:0010033 GO:0016020 GO:0016491 GO:0016614 GO:0016616 GO:0018130 GO:0019438 GO:0019637 GO:0019693 GO:0031090 GO:0031903 GO:0031974 GO:0031982 GO:0031983 GO:0032501 GO:0032943 GO:0034097 GO:0034641 GO:0034654 GO:0034774 GO:0036094 GO:0042221 GO:0042579 GO:0043167 GO:0043169 GO:0043226 GO:0043227 GO:0043229 GO:0043230 GO:0043231 GO:0043233 GO:0044237 GO:0044238 GO:0044249 GO:0044271 GO:0044281 GO:0045321 GO:0046037 GO:0046039 GO:0046390 GO:0046483 GO:0046649 GO:0046651 GO:0046872 GO:0048511 GO:0050896 GO:0051716 GO:0055086 GO:0060205 GO:0065010 GO:0070013 GO:0070062 GO:0070661 GO:0070670 GO:0070887 GO:0071310 GO:0071345 GO:0071353 GO:0071704 GO:0072521 GO:0072522 GO:0090407 GO:0097159 GO:0097292 GO:0097293 GO:0097294 GO:0098588 GO:0110165 GO:1901135 GO:1901137 GO:1901265 GO:1901293 GO:1901360 GO:1901362 GO:1901363 GO:1901564 GO:1901566 GO:1901576 GO:1903561 GO:1904813
133746	junction mediating and regulatory protein, p53 cofactor	JMY	Homo sapiens (human)	9606			'de novo' actin filament nucleation Arp2/3 complex binding Arp2/3 complex-mediated actin nucleation DNA damage response DNA metabolic process DNA repair actin binding actin filament organization actin nucleation actin polymerization-dependent cell motility apoptotic signaling pathway autophagosome membrane binding biological regulation biological_process bounding membrane of organelle cell communication cell leading edge cell motility cellular anatomical entity cellular aromatic compound metabolic process cellular component organization or biogenesis cellular component organization cellular metabolic process cellular nitrogen compound metabolic process cellular process cellular response to external stimulus cellular response to extracellular stimulus cellular response to nutrient levels cellular response to starvation cellular response to stimulus cellular response to stress cellular_component cytoplasm cytoplasmic vesicle cytoskeletal protein binding cytoskeleton endomembrane system heterocycle metabolic process intracellular membrane-bounded organelle intracellular non-membrane-bounded organelle intracellular organelle intracellular signal transduction intracellular vesicle intrinsic apoptotic signaling pathway by p53 class mediator intrinsic apoptotic signaling pathway macromolecule metabolic process membrane-bounded organelle membrane metabolic process microtubule binding molecular_function nitrogen compound metabolic process non-membrane-bounded organelle nucleic acid metabolic process nucleobase-containing compound metabolic process nucleoplasm nucleus organelle membrane organelle organic cyclic compound metabolic process organic substance metabolic process positive regulation of DNA-templated transcription positive regulation of RNA biosynthetic process positive regulation of RNA metabolic process positive regulation of apoptotic process positive regulation of biological process positive regulation of biosynthetic process positive regulation of cellular biosynthetic process positive regulation of cellular metabolic process positive regulation of cellular process positive regulation of macromolecule biosynthetic process positive regulation of macromolecule metabolic process positive regulation of metabolic process positive regulation of nitrogen compound metabolic process positive regulation of nucleobase-containing compound metabolic process positive regulation of programmed cell death primary metabolic process protein binding protein-containing complex binding regulation of DNA-templated transcription regulation of RNA biosynthetic process regulation of RNA metabolic process regulation of apoptotic process regulation of biological process regulation of biosynthetic process regulation of cellular biosynthetic process regulation of cellular metabolic process regulation of cellular process regulation of gene expression regulation of macromolecule biosynthetic process regulation of macromolecule metabolic process regulation of metabolic process regulation of nitrogen compound metabolic process regulation of nucleobase-containing compound metabolic process regulation of primary metabolic process regulation of programmed cell death regulation of transcription by RNA polymerase II response to external stimulus response to extracellular stimulus response to nutrient levels response to starvation response to stimulus response to stress signal transduction by p53 class mediator signal transduction supramolecular fiber organization transcription coactivator activity transcription coregulator activity transcription regulator activity tubulin binding vacuolar membrane vesicle	GO:0000421 GO:0003674 GO:0003712 GO:0003713 GO:0003779 GO:0005488 GO:0005515 GO:0005575 GO:0005634 GO:0005654 GO:0005737 GO:0005774 GO:0005856 GO:0006139 GO:0006259 GO:0006281 GO:0006355 GO:0006357 GO:0006725 GO:0006807 GO:0006950 GO:0006974 GO:0007015 GO:0007154 GO:0007165 GO:0008017 GO:0008092 GO:0008150 GO:0008152 GO:0009267 GO:0009605 GO:0009889 GO:0009891 GO:0009893 GO:0009987 GO:0009991 GO:0010468 GO:0010556 GO:0010557 GO:0010604 GO:0012505 GO:0015631 GO:0016020 GO:0016043 GO:0019219 GO:0019222 GO:0031090 GO:0031252 GO:0031323 GO:0031325 GO:0031326 GO:0031328 GO:0031410 GO:0031667 GO:0031668 GO:0031669 GO:0031982 GO:0033554 GO:0034314 GO:0034641 GO:0035556 GO:0042594 GO:0042981 GO:0043065 GO:0043067 GO:0043068 GO:0043170 GO:0043226 GO:0043227 GO:0043228 GO:0043229 GO:0043231 GO:0043232 GO:0044237 GO:0044238 GO:0044877 GO:0045010 GO:0045893 GO:0045935 GO:0046483 GO:0048518 GO:0048522 GO:0048870 GO:0050789 GO:0050794 GO:0050896 GO:0051171 GO:0051173 GO:0051252 GO:0051254 GO:0051716 GO:0060255 GO:0065007 GO:0070060 GO:0070358 GO:0071496 GO:0071704 GO:0071840 GO:0071933 GO:0072331 GO:0072332 GO:0080090 GO:0090304 GO:0097190 GO:0097193 GO:0097435 GO:0097708 GO:0098588 GO:0110165 GO:0140110 GO:1901360 GO:1902680 GO:2001141
51182	heat shock protein family A (Hsp70) member 14	HSPA14	Homo sapiens (human)	9606			'de novo' cotranslational protein folding 'de novo' post-translational protein folding 'de novo' protein folding ATP binding ATP hydrolysis activity ATP-dependent activity ATP-dependent protein folding chaperone adenyl nucleotide binding adenyl ribonucleotide binding anion binding binding biological_process carbohydrate derivative binding catalytic activity cellular anatomical entity cellular process cellular_component chaperone cofactor-dependent protein refolding chaperone-mediated protein folding cytoplasm cytosol heat shock protein binding heterocyclic compound binding hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity, acting on acid anhydrides hydrolase activity intracellular non-membrane-bounded organelle intracellular organelle ion binding membrane molecular_function non-membrane-bounded organelle nucleoside phosphate binding nucleotide binding organelle organic cyclic compound binding protein binding protein folding chaperone protein folding protein refolding purine nucleotide binding purine ribonucleoside triphosphate binding purine ribonucleotide binding pyrophosphatase activity ribonucleoside triphosphate phosphatase activity ribonucleotide binding ribosome small molecule binding	GO:0000166 GO:0003674 GO:0003824 GO:0005488 GO:0005515 GO:0005524 GO:0005575 GO:0005737 GO:0005829 GO:0005840 GO:0006457 GO:0006458 GO:0008150 GO:0009987 GO:0016020 GO:0016462 GO:0016787 GO:0016817 GO:0016818 GO:0016887 GO:0017076 GO:0017111 GO:0030554 GO:0031072 GO:0032553 GO:0032555 GO:0032559 GO:0035639 GO:0036094 GO:0042026 GO:0043167 GO:0043168 GO:0043226 GO:0043228 GO:0043229 GO:0043232 GO:0044183 GO:0051083 GO:0051084 GO:0051085 GO:0061077 GO:0097159 GO:0097367 GO:0110165 GO:0140657 GO:0140662 GO:1901265 GO:1901363
27000	DnaJ heat shock protein family (Hsp40) member C2	DNAJC2	Homo sapiens (human)	9606			'de novo' cotranslational protein folding 'de novo' protein folding ATPase activator activity ATPase regulator activity DNA metabolic process DNA replication Hsp70 protein binding RNA binding binding biological regulation biological_process cellular anatomical entity cellular aromatic compound metabolic process cellular component organization or biogenesis cellular component organization cellular metabolic process cellular nitrogen compound metabolic process cellular process cellular_component chromatin binding chromatin organization cytoplasm cytosol heat shock protein binding heterocycle metabolic process histone binding intracellular membrane-bounded organelle intracellular non-membrane-bounded organelle intracellular organelle macromolecule metabolic process membrane-bounded organelle membrane metabolic process modification-dependent protein binding molecular function activator activity molecular function regulator activity molecular_function negative regulation of DNA biosynthetic process negative regulation of DNA metabolic process negative regulation of biological process negative regulation of biosynthetic process negative regulation of cellular biosynthetic process negative regulation of cellular metabolic process negative regulation of cellular process negative regulation of macromolecule biosynthetic process negative regulation of macromolecule metabolic process negative regulation of metabolic process negative regulation of nitrogen compound metabolic process negative regulation of nucleobase-containing compound metabolic process nitrogen compound metabolic process non-membrane-bounded organelle nuclear membrane nucleic acid binding nucleic acid metabolic process nucleobase-containing compound metabolic process nucleolus nucleoplasm nucleus organelle membrane organelle organic cyclic compound binding organic cyclic compound metabolic process organic substance metabolic process positive regulation of DNA-templated transcription positive regulation of RNA biosynthetic process positive regulation of RNA metabolic process positive regulation of biological process positive regulation of biosynthetic process positive regulation of cellular biosynthetic process positive regulation of cellular metabolic process positive regulation of cellular process positive regulation of macromolecule biosynthetic process positive regulation of macromolecule metabolic process positive regulation of metabolic process positive regulation of nitrogen compound metabolic process positive regulation of nucleobase-containing compound metabolic process primary metabolic process protein binding protein folding protein-DNA complex organization protein-containing complex binding protein-containing complex organization protein-folding chaperone binding regulation of DNA biosynthetic process regulation of DNA metabolic process regulation of DNA-templated transcription regulation of RNA biosynthetic process regulation of RNA metabolic process regulation of biological process regulation of biological quality regulation of biosynthetic process regulation of cellular biosynthetic process regulation of cellular metabolic process regulation of cellular process regulation of cellular response to heat regulation of cellular response to stress regulation of gene expression regulation of macromolecule biosynthetic process regulation of macromolecule metabolic process regulation of metabolic process regulation of nitrogen compound metabolic process regulation of nucleobase-containing compound metabolic process regulation of primary metabolic process regulation of response to stimulus regulation of response to stress regulation of translational fidelity ribonucleoprotein complex binding ribosome binding ubiquitin modification-dependent histone binding ubiquitin-dependent protein binding ubiquitination-like modification-dependent protein binding	GO:0001671 GO:0003674 GO:0003676 GO:0003682 GO:0003723 GO:0005488 GO:0005515 GO:0005575 GO:0005634 GO:0005654 GO:0005730 GO:0005737 GO:0005829 GO:0006139 GO:0006259 GO:0006260 GO:0006325 GO:0006355 GO:0006450 GO:0006457 GO:0006458 GO:0006725 GO:0006807 GO:0008150 GO:0008152 GO:0009889 GO:0009890 GO:0009891 GO:0009892 GO:0009893 GO:0009987 GO:0010468 GO:0010556 GO:0010557 GO:0010558 GO:0010604 GO:0010605 GO:0016020 GO:0016043 GO:0019219 GO:0019222 GO:0030544 GO:0031072 GO:0031090 GO:0031323 GO:0031324 GO:0031325 GO:0031326 GO:0031327 GO:0031328 GO:0031965 GO:0034641 GO:0042393 GO:0043021 GO:0043022 GO:0043170 GO:0043226 GO:0043227 GO:0043228 GO:0043229 GO:0043231 GO:0043232 GO:0043933 GO:0044237 GO:0044238 GO:0044877 GO:0045893 GO:0045934 GO:0045935 GO:0046483 GO:0048518 GO:0048519 GO:0048522 GO:0048523 GO:0048583 GO:0050789 GO:0050794 GO:0051052 GO:0051053 GO:0051083 GO:0051087 GO:0051171 GO:0051172 GO:0051173 GO:0051252 GO:0051254 GO:0060255 GO:0060590 GO:0061649 GO:0065007 GO:0065008 GO:0071704 GO:0071824 GO:0071840 GO:0080090 GO:0080134 GO:0080135 GO:0090304 GO:0097159 GO:0098772 GO:0110165 GO:0140030 GO:0140035 GO:0140036 GO:0140677 GO:1900034 GO:1901360 GO:1902680 GO:2000278 GO:2000279 GO:2001141
3312	heat shock protein family A (Hsp70) member 8	HSPA8 Aliases: HSC70 HSC71 HSP73	Homo sapiens (human)	9606			'de novo' post-translational protein folding 'de novo' protein folding A1 adenosine receptor binding ADP binding ATP binding ATP hydrolysis activity ATP metabolic process ATP-dependent activity ATP-dependent protein disaggregase activity ATP-dependent protein folding chaperone C3HC4-type RING finger domain binding G protein-coupled receptor binding G1/S transition of mitotic cell cycle MHC class II protein complex binding MHC protein complex binding Prp19 complex RNA binding RNA metabolic process RNA processing RNA splicing, via transesterification reactions with bulged adenosine as nucleophile RNA splicing, via transesterification reactions RNA splicing adenosine receptor binding adenyl nucleotide binding adenyl ribonucleotide binding amide binding anatomical structure development anchoring junction animal organ development anion binding autophagosome autophagy axo-dendritic transport binding biological process involved in interaction with symbiont biological process involved in interspecies interaction between organisms biological process involved in symbiotic interaction biological regulation biological_process blood microparticle bounding membrane of organelle cadherin binding carbohydrate derivative binding carbohydrate derivative metabolic process catabolic process catalytic activity cell adhesion molecule binding cell communication cell cycle G1/S phase transition cell cycle phase transition cell cycle process cell junction maintenance cell junction organization cell junction cell projection cell surface cell-substrate junction cellular anatomical entity cellular aromatic compound metabolic process cellular catabolic process cellular component disassembly cellular component maintenance cellular component organization or biogenesis cellular component organization cellular localization cellular macromolecule localization cellular metabolic process cellular nitrogen compound metabolic process cellular process cellular response to cadmium ion cellular response to chemical stimulus cellular response to chemical stress cellular response to endogenous stimulus cellular response to external stimulus cellular response to extracellular stimulus cellular response to heat cellular response to hormone stimulus cellular response to hydrogen peroxide cellular response to inorganic substance cellular response to lipid cellular response to metal ion cellular response to nutrient levels cellular response to organic cyclic compound cellular response to organic substance cellular response to oxidative stress cellular response to oxygen-containing compound cellular response to reactive oxygen species cellular response to starvation cellular response to steroid hormone stimulus cellular response to stimulus cellular response to stress cellular_component cerebellum development chaperone cofactor-dependent protein refolding chaperone-mediated autophagy translocation complex disassembly chaperone-mediated autophagy chaperone-mediated protein folding clathrin coat disassembly clathrin-coated vesicle membrane clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane clathrin-uncoating ATPase activity coated vesicle membrane cytoplasm cytoplasmic vesicle lumen cytoplasmic vesicle membrane cytoplasmic vesicle cytoskeleton-dependent intracellular transport cytosol cytosolic region dendritic shaft dendritic spine developmental process endosome enzyme binding establishment of localization in cell establishment of localization establishment of protein localization to organelle establishment of protein localization to vacuole establishment of protein localization estrous cycle exocytic vesicle extracellular exosome extracellular membrane-bounded organelle extracellular organelle extracellular region extracellular space extracellular vesicle fatty acid derivative binding ficolin-1-rich granule lumen focal adhesion forebrain development glutamatergic synapse glycinergic synapse heat shock protein binding heterocycle metabolic process heterocyclic compound binding hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity, acting on acid anhydrides hydrolase activity import into nucleus intermediate filament intracellular membrane-bounded organelle intracellular non-membrane-bounded organelle intracellular organelle lumen intracellular organelle intracellular protein transport intracellular protein-containing complex intracellular transport intracellular vesicle ion binding kidney development late endosomal microautophagy late endosome lipid binding localization lumenal side of lysosomal membrane lumenal side of membrane lysosomal lumen lysosomal matrix lysosomal membrane organization lysosomal membrane lytic vacuole membrane mRNA metabolic process mRNA processing mRNA splicing, via spliceosome macromolecule catabolic process macromolecule localization macromolecule metabolic process maintenance of postsynaptic specialization structure maintenance of synapse structure melanosome membrane organization membrane-bounded organelle membrane-enclosed lumen membrane metabolic process microautophagy microtubule-based movement microtubule-based process microtubule-based transport microtubule mitotic cell cycle phase transition mitotic cell cycle process modified amino acid binding modulation by host of symbiont process modulation by host of viral genome replication modulation by host of viral process molecular adaptor activity molecular carrier activity molecular function activator activity molecular function regulator activity molecular_function multicellular organismal reproductive process muscle tissue development negative regulation of DNA-templated transcription negative regulation of NLRP3 inflammasome complex assembly negative regulation of RNA biosynthetic process negative regulation of RNA metabolic process negative regulation of apoptotic process negative regulation of biological process negative regulation of biosynthetic process negative regulation of cardiac muscle cell apoptotic process negative regulation of cellular biosynthetic process negative regulation of cellular component organization negative regulation of cellular metabolic process negative regulation of cellular process negative regulation of macromolecule biosynthetic process negative regulation of macromolecule metabolic process negative regulation of metabolic process negative regulation of muscle cell apoptotic process negative regulation of nitrogen compound metabolic process negative regulation of nucleobase-containing compound metabolic process negative regulation of programmed cell death negative regulation of protein-containing complex assembly negative regulation of striated muscle cell apoptotic process negative regulation of supramolecular fiber organization neuron projection neuron spine nitrogen compound metabolic process nitrogen compound transport non-membrane-bounded organelle nuclear protein-containing complex nuclear transport nucleic acid binding nucleic acid metabolic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleocytoplasmic transport nucleolus nucleoplasm nucleoside phosphate binding nucleoside phosphate metabolic process nucleoside triphosphate metabolic process nucleotide binding nucleotide metabolic process nucleus organelle lumen organelle membrane organelle organization organelle organic cyclic compound binding organic cyclic compound metabolic process organic substance catabolic process organic substance metabolic process organic substance transport organonitrogen compound catabolic process organonitrogen compound metabolic process organophosphate metabolic process ovulation cycle peptide binding perikaryon perinuclear region of cytoplasm phosphate-containing compound metabolic process phosphatidylserine binding phospholipid binding phosphorus metabolic process photoreceptor inner segment photoreceptor ribbon synapse pigment granule plasma membrane bounded cell projection plasma membrane region plasma membrane polymeric cytoskeletal fiber positive regulation by host of viral genome replication positive regulation by host of viral process positive regulation of RNA metabolic process positive regulation of RNA splicing positive regulation of T cell mediated cytotoxicity positive regulation of T cell mediated immunity positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains positive regulation of adaptive immune response positive regulation of biological process positive regulation of biosynthetic process positive regulation of cell killing positive regulation of cell migration positive regulation of cell motility positive regulation of cellular biosynthetic process positive regulation of cellular component organization positive regulation of cellular metabolic process positive regulation of cellular process positive regulation of endocytosis positive regulation of gene expression positive regulation of immune effector process positive regulation of immune response positive regulation of immune system process positive regulation of leukocyte mediated cytotoxicity positive regulation of leukocyte mediated immunity positive regulation of locomotion positive regulation of lymphocyte mediated immunity positive regulation of lysosomal membrane permeability positive regulation of mRNA metabolic process positive regulation of mRNA processing positive regulation of mRNA splicing, via spliceosome positive regulation of macromolecule biosynthetic process positive regulation of macromolecule metabolic process positive regulation of membrane permeability positive regulation of metabolic process positive regulation of nitrogen compound metabolic process positive regulation of nucleobase-containing compound metabolic process positive regulation of phagocytosis positive regulation of protein folding positive regulation of protein metabolic process positive regulation of protein refolding positive regulation of proteolysis positive regulation of response to stimulus positive regulation of transport postsynapse postsynaptic cytosol postsynaptic density organization postsynaptic density postsynaptic specialization membrane postsynaptic specialization organization postsynaptic specialization presynapse presynaptic cytosol primary metabolic process process utilizing autophagic mechanism prostaglandin binding protein binding protein carrier chaperone protein catabolic process protein depolymerization protein domain specific binding protein folding chaperone complex protein folding chaperone protein folding protein import into nucleus protein localization to lysosome protein localization to nucleus protein localization to organelle protein localization to vacuole protein localization protein metabolic process protein refolding protein targeting to lysosome involved in chaperone-mediated autophagy protein targeting to lysosome protein targeting to vacuole involved in autophagy protein targeting to vacuole protein targeting protein transmembrane import into intracellular organelle protein transmembrane transport protein transport protein-containing complex binding protein-containing complex destabilizing activity protein-containing complex disassembly protein-containing complex organization protein-containing complex protein-folding chaperone binding protein-macromolecule adaptor activity purine nucleoside triphosphate metabolic process purine nucleotide binding purine nucleotide metabolic process purine ribonucleoside triphosphate binding purine ribonucleoside triphosphate metabolic process purine ribonucleotide binding purine ribonucleotide metabolic process purine-containing compound metabolic process pyrophosphatase activity receptor ligand activity regulation of DNA-templated transcription regulation of NLRP3 inflammasome complex assembly regulation of RNA biosynthetic process regulation of RNA metabolic process regulation of RNA splicing regulation of T cell mediated cytotoxicity regulation of T cell mediated immunity regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains regulation of adaptive immune response regulation of apoptotic process regulation of biological process regulation of biological quality regulation of biosynthetic process regulation of cardiac muscle cell apoptotic process regulation of cell cycle regulation of cell killing regulation of cell migration regulation of cell motility regulation of cellular biosynthetic process regulation of cellular component biogenesis regulation of cellular component organization regulation of cellular localization regulation of cellular metabolic process regulation of cellular process regulation of endocytosis regulation of establishment of protein localization regulation of gene expression regulation of immune effector process regulation of immune response regulation of immune system process regulation of leukocyte mediated cytotoxicity regulation of leukocyte mediated immunity regulation of localization regulation of locomotion regulation of lymphocyte mediated immunity regulation of lysosomal membrane permeability regulation of mRNA metabolic process regulation of mRNA processing regulation of mRNA splicing, via spliceosome regulation of macromolecule biosynthetic process regulation of macromolecule metabolic process regulation of membrane permeability regulation of metabolic process regulation of muscle cell apoptotic process regulation of nitrogen compound metabolic process regulation of nucleobase-containing compound metabolic process regulation of phagocytosis regulation of postsynapse organization regulation of primary metabolic process regulation of programmed cell death regulation of protein complex stability regulation of protein folding regulation of protein import regulation of protein localization regulation of protein metabolic process regulation of protein refolding regulation of protein stability regulation of protein transport regulation of protein-containing complex assembly regulation of proteolysis regulation of response to stimulus regulation of striated muscle cell apoptotic process regulation of supramolecular fiber organization regulation of synapse organization regulation of transport regulation of vesicle-mediated transport reproductive process response to abiotic stimulus response to activity response to alcohol response to cadmium ion response to chemical response to endogenous stimulus response to estradiol response to ethanol response to external stimulus response to extracellular stimulus response to heat response to hormone response to hydrogen peroxide response to inorganic substance response to ketone response to lipid response to metal ion response to nickel cation response to nutrient levels response to odorant response to organic cyclic compound response to organic substance response to oxidative stress response to oxygen-containing compound response to progesterone response to reactive oxygen species response to starvation response to steroid hormone response to stimulus response to stress response to temperature stimulus response to topologically incorrect protein response to unfolded protein response to xenobiotic stimulus rhythmic process ribbon synapse ribonucleoprotein complex ribonucleoside triphosphate metabolic process ribonucleoside triphosphate phosphatase activity ribonucleotide binding ribonucleotide metabolic process ribose phosphate metabolic process secretory granule lumen secretory vesicle side of membrane signal transduction signaling receptor activator activity signaling receptor binding signaling receptor regulator activity skeletal muscle tissue development slow axonal transport small molecule binding small molecule metabolic process spliceosomal complex supramolecular complex supramolecular fiber supramolecular polymer synapse organization synapse synaptic membrane synaptic vesicle uncoating synaptic vesicle terminal bouton tissue development transmembrane transport transport along microtubule transport vesicle transport ubiquitin protein ligase binding ubiquitin-like protein ligase binding unfolded protein binding vacuolar lumen vacuolar membrane vacuole vesicle lumen vesicle membrane vesicle uncoating vesicle	GO:0000082 GO:0000166 GO:0000302 GO:0000375 GO:0000377 GO:0000398 GO:0000974 GO:0001664 GO:0001786 GO:0001822 GO:0001910 GO:0001912 GO:0001914 GO:0001916 GO:0001917 GO:0002682 GO:0002684 GO:0002697 GO:0002699 GO:0002703 GO:0002705 GO:0002706 GO:0002708 GO:0002709 GO:0002711 GO:0002819 GO:0002821 GO:0002822 GO:0002824 GO:0003674 GO:0003676 GO:0003723 GO:0003824 GO:0005102 GO:0005488 GO:0005515 GO:0005524 GO:0005543 GO:0005575 GO:0005576 GO:0005615 GO:0005634 GO:0005654 GO:0005681 GO:0005730 GO:0005737 GO:0005765 GO:0005768 GO:0005770 GO:0005773 GO:0005774 GO:0005775 GO:0005776 GO:0005829 GO:0005874 GO:0005882 GO:0005886 GO:0005925 GO:0006139 GO:0006163 GO:0006355 GO:0006396 GO:0006397 GO:0006457 GO:0006458 GO:0006605 GO:0006606 GO:0006622 GO:0006623 GO:0006725 GO:0006753 GO:0006793 GO:0006796 GO:0006807 GO:0006810 GO:0006886 GO:0006913 GO:0006914 GO:0006950 GO:0006979 GO:0006986 GO:0006996 GO:0007017 GO:0007018 GO:0007154 GO:0007165 GO:0007519 GO:0008021 GO:0008088 GO:0008104 GO:0008150 GO:0008152 GO:0008289 GO:0008380 GO:0009056 GO:0009057 GO:0009117 GO:0009141 GO:0009144 GO:0009150 GO:0009199 GO:0009205 GO:0009259 GO:0009266 GO:0009267 GO:0009408 GO:0009410 GO:0009605 GO:0009628 GO:0009719 GO:0009725 GO:0009888 GO:0009889 GO:0009890 GO:0009891 GO:0009892 GO:0009893 GO:0009986 GO:0009987 GO:0009991 GO:0010033 GO:0010035 GO:0010038 GO:0010045 GO:0010468 GO:0010556 GO:0010557 GO:0010558 GO:0010604 GO:0010605 GO:0010628 GO:0010656 GO:0010660 GO:0010662 GO:0010664 GO:0010665 GO:0010667 GO:0010970 GO:0012506 GO:0014069 GO:0014070 GO:0014823 GO:0015031 GO:0016020 GO:0016043 GO:0016070 GO:0016071 GO:0016191 GO:0016237 GO:0016462 GO:0016787 GO:0016817 GO:0016818 GO:0016887 GO:0017076 GO:0017111 GO:0019219 GO:0019222 GO:0019538 GO:0019637 GO:0019693 GO:0019899 GO:0019904 GO:0021549 GO:0022402 GO:0022411 GO:0022414 GO:0023023 GO:0023026 GO:0030054 GO:0030055 GO:0030100 GO:0030133 GO:0030162 GO:0030163 GO:0030334 GO:0030335 GO:0030545 GO:0030546 GO:0030554 GO:0030659 GO:0030662 GO:0030665 GO:0030674 GO:0030705 GO:0030900 GO:0031072 GO:0031090 GO:0031323 GO:0031324 GO:0031325 GO:0031326 GO:0031327 GO:0031328 GO:0031333 GO:0031341 GO:0031343 GO:0031410 GO:0031625 GO:0031647 GO:0031667 GO:0031668 GO:0031669 GO:0031685 GO:0031686 GO:0031974 GO:0031982 GO:0031983 GO:0032355 GO:0032502 GO:0032553 GO:0032555 GO:0032559 GO:0032570 GO:0032870 GO:0032879 GO:0032880 GO:0032984 GO:0032991 GO:0033036 GO:0033120 GO:0033218 GO:0033365 GO:0033554 GO:0033993 GO:0034330 GO:0034331 GO:0034504 GO:0034599 GO:0034605 GO:0034614 GO:0034641 GO:0034774 GO:0035639 GO:0035966 GO:0036094 GO:0040012 GO:0040017 GO:0042026 GO:0042221 GO:0042277 GO:0042470 GO:0042542 GO:0042594 GO:0042698 GO:0042981 GO:0042995 GO:0043005 GO:0043066 GO:0043067 GO:0043069 GO:0043167 GO:0043168 GO:0043170 GO:0043195 GO:0043197 GO:0043198 GO:0043202 GO:0043204 GO:0043226 GO:0043227 GO:0043228 GO:0043229 GO:0043230 GO:0043231 GO:0043232 GO:0043233 GO:0043254 GO:0043484 GO:0043531 GO:0043933 GO:0043954 GO:0044087 GO:0044183 GO:0044237 GO:0044238 GO:0044248 GO:0044281 GO:0044309 GO:0044389 GO:0044403 GO:0044419 GO:0044743 GO:0044770 GO:0044772 GO:0044788 GO:0044794 GO:0044827 GO:0044829 GO:0044843 GO:0044849 GO:0044877 GO:0045184 GO:0045202 GO:0045296 GO:0045471 GO:0045807 GO:0045862 GO:0045892 GO:0045934 GO:0045935 GO:0046034 GO:0046483 GO:0046686 GO:0046907 GO:0048018 GO:0048024 GO:0048026 GO:0048471 GO:0048511 GO:0048513 GO:0048518 GO:0048519 GO:0048522 GO:0048523 GO:0048545 GO:0048583 GO:0048584 GO:0048609 GO:0048770 GO:0048856 GO:0050684 GO:0050685 GO:0050764 GO:0050766 GO:0050776 GO:0050778 GO:0050789 GO:0050794 GO:0050807 GO:0050808 GO:0050839 GO:0050896 GO:0051049 GO:0051050 GO:0051082 GO:0051084 GO:0051085 GO:0051087 GO:0051128 GO:0051129 GO:0051130 GO:0051169 GO:0051170 GO:0051171 GO:0051172 GO:0051173 GO:0051179 GO:0051223 GO:0051234 GO:0051246 GO:0051247 GO:0051252 GO:0051253 GO:0051254 GO:0051261 GO:0051641 GO:0051649 GO:0051702 GO:0051716 GO:0051726 GO:0051851 GO:0055085 GO:0055086 GO:0055131 GO:0060090 GO:0060205 GO:0060255 GO:0060341 GO:0060537 GO:0060627 GO:0061024 GO:0061077 GO:0061083 GO:0061202 GO:0061462 GO:0061635 GO:0061684 GO:0061738 GO:0061740 GO:0061919 GO:0062197 GO:0065007 GO:0065008 GO:0065010 GO:0070013 GO:0070062 GO:0070161 GO:0070201 GO:0070301 GO:0070382 GO:0070727 GO:0070887 GO:0071211 GO:0071241 GO:0071248 GO:0071276 GO:0071310 GO:0071383 GO:0071396 GO:0071407 GO:0071495 GO:0071496 GO:0071702 GO:0071704 GO:0071705 GO:0071806 GO:0071840 GO:0072318 GO:0072319 GO:0072341 GO:0072521 GO:0072562 GO:0072594 GO:0072665 GO:0072666 GO:0080090 GO:0090304 GO:0090559 GO:0097060 GO:0097106 GO:0097159 GO:0097212 GO:0097213 GO:0097214 GO:0097305 GO:0097367 GO:0097470 GO:0097708 GO:0098552 GO:0098575 GO:0098576 GO:0098588 GO:0098590 GO:0098684 GO:0098690 GO:0098772 GO:0098793 GO:0098794 GO:0098852 GO:0098880 GO:0098978 GO:0099080 GO:0099081 GO:0099084 GO:0099111 GO:0099175 GO:0099503 GO:0099512 GO:0099513 GO:0099522 GO:0099523 GO:0099524 GO:0099558 GO:0099572 GO:0099634 GO:0101031 GO:0110165 GO:0120025 GO:0140104 GO:0140513 GO:0140535 GO:0140545 GO:0140597 GO:0140657 GO:0140662 GO:0140677 GO:0140776 GO:1900225 GO:1900226 GO:1901135 GO:1901265 GO:1901360 GO:1901363 GO:1901564 GO:1901565 GO:1901567 GO:1901575 GO:1901654 GO:1901700 GO:1901701 GO:1902679 GO:1902903 GO:1902904 GO:1903047 GO:1903311 GO:1903313 GO:1903332 GO:1903334 GO:1903561 GO:1904589 GO:1904592 GO:1904593 GO:1904764 GO:1904813 GO:1905710 GO:1990832 GO:1990833 GO:1990834 GO:1990836 GO:1990904 GO:2000145 GO:2000147 GO:2001141
957	ectonucleoside triphosphate diphosphohydrolase 5 (inactive)	ENTPD5 Aliases: NTPDase-5	Homo sapiens (human)	9606			'de novo' post-translational protein folding 'de novo' protein folding ADP phosphatase activity CDP phosphatase activity GDP phosphatase activity IDP phosphatase activity UDP catabolic process UDP metabolic process UDP phosphatase activity UDP-glucose metabolic process aromatic compound catabolic process binding biological_process carbohydrate derivative catabolic process carbohydrate derivative metabolic process catabolic process catalytic activity cellular anatomical entity cellular aromatic compound metabolic process cellular catabolic process cellular metabolic process cellular nitrogen compound catabolic process cellular nitrogen compound metabolic process cellular process cellular_component endoplasmic reticulum extracellular region extracellular space glycosylation heterocycle catabolic process heterocycle metabolic process hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity, acting on acid anhydrides hydrolase activity intracellular membrane-bounded organelle intracellular organelle macromolecule glycosylation macromolecule metabolic process macromolecule modification membrane-bounded organelle membrane metabolic process molecular_function nitrogen compound metabolic process nucleobase-containing compound catabolic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoside diphosphate catabolic process nucleoside diphosphate metabolic process nucleoside diphosphate phosphatase activity nucleoside phosphate catabolic process nucleoside phosphate metabolic process nucleotide catabolic process nucleotide metabolic process nucleotide-sugar metabolic process organelle organic cyclic compound catabolic process organic cyclic compound metabolic process organic substance catabolic process organic substance metabolic process organonitrogen compound catabolic process organonitrogen compound metabolic process organophosphate catabolic process organophosphate metabolic process phosphate-containing compound metabolic process phosphorus metabolic process primary metabolic process protein N-linked glycosylation protein binding protein folding protein glycosylation protein metabolic process protein modification process pyrimidine nucleoside diphosphate catabolic process pyrimidine nucleoside diphosphate metabolic process pyrimidine nucleotide catabolic process pyrimidine nucleotide metabolic process pyrimidine ribonucleoside diphosphate catabolic process pyrimidine ribonucleoside diphosphate metabolic process pyrimidine ribonucleotide catabolic process pyrimidine ribonucleotide metabolic process pyrimidine-containing compound catabolic process pyrimidine-containing compound metabolic process pyrophosphatase activity ribonucleoside diphosphate catabolic process ribonucleoside diphosphate metabolic process ribonucleoside triphosphate phosphatase activity ribonucleotide catabolic process ribonucleotide metabolic process ribose phosphate metabolic process small molecule metabolic process	GO:0003674 GO:0003824 GO:0004382 GO:0005488 GO:0005515 GO:0005575 GO:0005576 GO:0005615 GO:0005783 GO:0006011 GO:0006139 GO:0006220 GO:0006244 GO:0006256 GO:0006457 GO:0006458 GO:0006486 GO:0006487 GO:0006725 GO:0006753 GO:0006793 GO:0006796 GO:0006807 GO:0008150 GO:0008152 GO:0009056 GO:0009117 GO:0009132 GO:0009134 GO:0009138 GO:0009140 GO:0009166 GO:0009185 GO:0009191 GO:0009193 GO:0009195 GO:0009218 GO:0009222 GO:0009225 GO:0009259 GO:0009261 GO:0009987 GO:0016020 GO:0016462 GO:0016787 GO:0016817 GO:0016818 GO:0017110 GO:0017111 GO:0019439 GO:0019538 GO:0019637 GO:0019693 GO:0034641 GO:0034655 GO:0036211 GO:0036384 GO:0043170 GO:0043226 GO:0043227 GO:0043229 GO:0043231 GO:0043262 GO:0043412 GO:0043413 GO:0044237 GO:0044238 GO:0044248 GO:0044270 GO:0044281 GO:0045134 GO:0046048 GO:0046434 GO:0046483 GO:0046700 GO:0051084 GO:0055086 GO:0070085 GO:0071704 GO:0072527 GO:0072529 GO:0110165 GO:1901135 GO:1901136 GO:1901292 GO:1901360 GO:1901361 GO:1901564 GO:1901565 GO:1901575 GO:1990003
3303	heat shock protein family A (Hsp70) member 1A	HSPA1A	Homo sapiens (human)	9606			'de novo' post-translational protein folding 'de novo' protein folding ATP binding ATP hydrolysis activity ATP metabolic process ATP-dependent activity ATP-dependent protein disaggregase activity ATP-dependent protein folding chaperone C3HC4-type RING finger domain binding COP9 signalosome G protein-coupled receptor binding RNA binding RNA catabolic process RNA metabolic process adenyl nucleotide binding adenyl ribonucleotide binding aggresome anchoring junction anion binding aromatic compound catabolic process binding biological process involved in interaction with host biological process involved in interspecies interaction between organisms biological process involved in symbiotic interaction biological regulation biological_process blood microparticle cadherin binding carbohydrate derivative binding carbohydrate derivative metabolic process catabolic process catalytic activity cell adhesion molecule binding cell junction cell-substrate junction cellular anatomical entity cellular aromatic compound metabolic process cellular catabolic process cellular component assembly cellular component organization or biogenesis cellular component organization cellular heat acclimation cellular localization cellular metabolic process cellular nitrogen compound catabolic process cellular nitrogen compound metabolic process cellular process cellular response to chemical stimulus cellular response to chemical stress cellular response to endogenous stimulus cellular response to heat cellular response to hormone stimulus cellular response to lipid cellular response to organic cyclic compound cellular response to organic substance cellular response to oxidative stress cellular response to steroid hormone stimulus cellular response to stimulus cellular response to stress cellular response to topologically incorrect protein cellular response to unfolded protein cellular_component centriole centrosome chaperone cofactor-dependent protein refolding chaperone-mediated protein complex assembly chaperone-mediated protein folding cytoplasm cytosol death receptor agonist activity denatured protein binding disordered domain specific binding endoplasmic reticulum entry into host enzyme binding establishment of localization in cell establishment of localization exogenous protein binding extracellular exosome extracellular membrane-bounded organelle extracellular organelle extracellular region extracellular space extracellular vesicle ficolin-1-rich granule lumen focal adhesion heat acclimation heat shock protein binding heterocycle catabolic process heterocycle metabolic process heterocyclic compound binding histone deacetylase binding hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity, acting on acid anhydrides hydrolase activity inclusion body intracellular anatomical structure intracellular membrane-bounded organelle intracellular non-membrane-bounded organelle intracellular organelle lumen intracellular organelle intracellular transport ion binding localization lysosomal transport mRNA catabolic process mRNA metabolic process macromolecule catabolic process macromolecule metabolic process membrane organization membrane-bounded organelle membrane-enclosed lumen metabolic process microtubule organizing center misfolded protein binding mitochondrial membrane organization mitochondrion organization mitochondrion molecular function activator activity molecular function inhibitor activity molecular function regulator activity molecular_function movement in host negative regulation of DNA-templated transcription negative regulation of RNA biosynthetic process negative regulation of RNA metabolic process negative regulation of apoptotic process negative regulation of apoptotic signaling pathway negative regulation of biological process negative regulation of biosynthetic process negative regulation of cell communication negative regulation of cell growth negative regulation of cell population proliferation negative regulation of cellular biosynthetic process negative regulation of cellular component organization negative regulation of cellular metabolic process negative regulation of cellular process negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway negative regulation of extrinsic apoptotic signaling pathway in absence of ligand negative regulation of extrinsic apoptotic signaling pathway negative regulation of gene expression negative regulation of growth negative regulation of inclusion body assembly negative regulation of intracellular signal transduction negative regulation of intrinsic apoptotic signaling pathway negative regulation of macromolecule biosynthetic process negative regulation of macromolecule metabolic process negative regulation of membrane permeability negative regulation of metabolic process negative regulation of mitochondrial membrane permeability negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway negative regulation of mitochondrion organization negative regulation of nitrogen compound metabolic process negative regulation of nucleobase-containing compound metabolic process negative regulation of organelle organization negative regulation of post-translational protein modification negative regulation of programmed cell death negative regulation of protein metabolic process negative regulation of protein modification by small protein conjugation or removal negative regulation of protein modification process negative regulation of protein ubiquitination negative regulation of response to endoplasmic reticulum stress negative regulation of response to stimulus negative regulation of signal transduction in absence of ligand negative regulation of signal transduction negative regulation of signaling negative regulation of transcription by RNA polymerase II negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway nitrogen compound metabolic process non-membrane-bounded organelle nuclear body nuclear protein-containing complex nuclear speck nucleic acid binding nucleic acid metabolic process nucleobase-containing compound catabolic process nucleobase-containing compound metabolic process nucleobase-containing small molecule metabolic process nucleoplasm nucleoside phosphate binding nucleoside phosphate metabolic process nucleoside triphosphate metabolic process nucleotide binding nucleotide metabolic process nucleus organelle lumen organelle organization organelle organic cyclic compound binding organic cyclic compound catabolic process organic cyclic compound metabolic process organic substance catabolic process organic substance metabolic process organonitrogen compound metabolic process organophosphate metabolic process perinuclear region of cytoplasm phosphate-containing compound metabolic process phosphorus metabolic process positive regulation of DNA-binding transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of RNA metabolic process positive regulation of RNA splicing positive regulation of biological process positive regulation of biosynthetic process positive regulation of catabolic process positive regulation of catalytic activity positive regulation of cell communication positive regulation of cell differentiation positive regulation of cellular biosynthetic process positive regulation of cellular component biogenesis positive regulation of cellular component organization positive regulation of cellular metabolic process positive regulation of cellular process positive regulation of cytokine production positive regulation of cytokine-mediated signaling pathway positive regulation of cytoskeleton organization positive regulation of defense response positive regulation of developmental process positive regulation of endoribonuclease activity positive regulation of erythrocyte differentiation positive regulation of gene expression positive regulation of hydrolase activity positive regulation of immune response

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