elovl7b ELOVL fatty acid elongase 7b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: elovl7bprovided by ZNC
Official Full Name: ELOVL fatty acid elongase 7bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-5485
See related: Ensembl:ENSDARG00000100185 AllianceGenome:ZFIN:ZDB-GENE-030131-5485
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: elovl1; zgc:56422; wu:fd20a06
Summary: Predicted to enable fatty acid elongase activity. Predicted to be involved in fatty acid biosynthetic process and sphingolipid biosynthetic process. Predicted to act upstream of or within fatty acid biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be integral component of endoplasmic reticulum membrane. Is expressed in EVL; epidermal superficial stratum; pectoral fin; periderm; and pharynx. Orthologous to human ELOVL7 (ELOVL fatty acid elongase 7). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information: Annotation category: partial on reference assembly
Orthologs: all
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Genomic context

Location:: chromosome: 10

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	Unplaced Scaffold	NW_003334902.1 (3100..5808, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	Unplaced Scaffold	NW_003334902.1 (3100..5808, complement)

NW_003334902.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

both elovl1 genes are a key determinant of swim bladder and kidney development in zebrafish.
Title: The fatty acid chain elongase, Elovl1, is required for kidney and swim bladder development during zebrafish embryogenesis.

Submit: New GeneRIF Correction

General gene information

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Markers

z44989 (e-PCR), detects polymorphism
- UniSTS:238636

AI722167 (e-PCR)
- UniSTS:206024

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables fatty acid elongase activity	IBA Inferred from Biological aspect of Ancestor more info
enables fatty acid elongase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within fatty acid biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in fatty acid elongation, monounsaturated fatty acid	IBA Inferred from Biological aspect of Ancestor more info
involved_in fatty acid elongation, polyunsaturated fatty acid	IBA Inferred from Biological aspect of Ancestor more info
involved_in fatty acid elongation, saturated fatty acid	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within fatty acid elongation, saturated fatty acid	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within fatty acid metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within lipid metabolic process	IEA Inferred from Electronic Annotation more info
involved_in long-chain fatty-acyl-CoA biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in sphingolipid biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in unsaturated fatty acid biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in very long-chain fatty acid biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within very long-chain fatty acid biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: very long chain fatty acid elongase 7

Names: ELOVL family member 7, elongation of long chain fatty acids b; elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1

NP_956072.1

EC 2.3.1.199

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.