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    lepA translation elongation factor 4 [ Cronobacter malonaticus LMG 23826 ]

    Gene ID: 45714532, updated on 6-Oct-2023

    Summary

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    Gene symbol
    lepA
    Gene description
    translation elongation factor 4
    Locus tag
    AFK66_RS04190
    Gene type
    protein coding
    Organism
    Cronobacter malonaticus LMG 23826 (strain: LMG 23826, culture-collection: LMG:23826, type-material: type strain of Cronobacter malonaticus)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Cronobacter
    Old locus tag
    AFK66_004420
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    Genomic context

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    NZ_CP013940.1Genomic Context describing neighboring genes Neighboring gene anti-sigma-E factor RseA Neighboring gene sigma-E factor regulatory protein RseB Neighboring gene SoxR-reducing system protein RseC Neighboring gene signal peptidase I Neighboring gene ribonuclease III Neighboring gene GTPase Era

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_CP013940.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EF4 reveals the energy barrier for tRNA back-translocation in the peptidyl transferase center. Song G, et al. RNA Biol, 2016 Oct 2. PMID 27472653, Free PMC Article
    2. The conserved protein EF4 (LepA) modulates the elongation cycle of protein synthesis. Liu H, et al. Proc Natl Acad Sci U S A, 2011 Sep 27. PMID 21930951, Free PMC Article
    3. Conserved GTPase LepA (Elongation Factor 4) functions in biogenesis of the 30S subunit of the 70S ribosome. Gibbs MR, et al. Proc Natl Acad Sci U S A, 2017 Jan 31. PMID 28096346, Free PMC Article
    4. Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome. Kumar V, et al. J Biol Chem, 2016 Jun 17. PMID 27137929, Free PMC Article
    5. Fully Closed Genome Sequences of Five Type Strains of the Genus Cronobacter and One Cronobacter sakazakii Strain. Moine D, et al. Genome Announc, 2016 Mar 24. PMID 27013041, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    translation elongation factor 4
    WP_004387377.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_CP013940.1 Reference assembly

      Range
      904664..906463
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_004387377.1 MULTISPECIES: translation elongation factor 4 [Cronobacter]

      See identical proteins and their annotated locations for WP_004387377.1

      UniProtKB/Swiss-Prot
      A7MH13
      UniProtKB/TrEMBL
      A0A2S9U9N2, K8CSY1, K8DBM6, V5TVN9
    Nucleotide Protein
    Heading Accession and Version