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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Hepatic triacylglycerol lipase
Summary
- UniProt ID
- P11150
- Gene Symbol
-
- LIPC
- HTGL
- Organism
- Homo sapiens (human)
External Links
- PubChem
- P11150
- SwissLipids
- The Human Metabolome Database
- HMDBP00226
Annotation
- Keyword
-
- Direct protein sequencing
- Disease variant
- Glycoprotein
- HDL
- Heparin-binding
- Hydrolase
- Lipid degradation
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| chylomicron remnant clearance |
| triglyceride homeostasis |
| GO Term |
|---|
| extracellular region |
| extracellular space |
| endoplasmic reticulum lumen |
| high-density lipoprotein particle |
| GO Term |
|---|
| phosphatidyl phospholipase B activity |
Sequence
MDTSPLCFSILLVLCIFIQSSALGQSLKPEPFGRRAQAVETNKTLHEMKTRFLLFGETNQGCQIRINHPDTLQECGFNSSLPLVMIIHGWSVDGVLENWIWQMVAALKSQPAQPVNVGLVDWITLAHDHYTIAVRNTRLVGKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSSIGGTHKIGRITGLDAAGPLFEGSAPSNRLSPDDANFVDAIHTFTREHMGLSVGIKQPIGHYDFYPNGGSFQPGCHFLELYRHIAQHGFNAITQTIKCSHERSVHLFIDSLLHAGTQSMAYPCGDMNSFSQGLCLSCKKGRCNTLGYHVRQEPRSKSKRLFLVTRAQSPFKVYHYQFKIQFINQTETPIQTTFTMSLLGTKEKMQKIPITLGKGIASNKTYSFLITLDVDIGELIMIKFKWENSAVWANVWDTVQTIIPWSTGPRHSGLVLKTIRVKAGETQQRMTFCSENTDDLLLRPTQEKIFVKCEIKSKTSKRKIR
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Assembly of active LPL and LIPC lipase complexes | Homo sapiens |
| Chylomicron clearance | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10952 | nephritis | |
| DOID:10966 | lipoid nephrosis | |
| DOID:114 | heart disease | |
| DOID:11634 | myxedema | |
| DOID:1168 | familial hyperlipidemia | |
| DOID:11716 | prediabetes syndrome | |
| DOID:11801 | protein-energy malnutrition | |
| DOID:1184 | nephrotic syndrome | |
| DOID:11847 | coronary thrombosis | |
| DOID:11870 | Pick's disease |
