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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
E-selectin
Summary
- UniProt ID
- P16581
- Gene Symbol
-
- SELE
- ELAM1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cell adhesion
- Cell membrane
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Lectin
- Metal-binding
- Reference proteome
- Repeat
- Signal
- Sushi
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| regulation of inflammatory response |
| calcium-mediated signaling |
| actin filament-based process |
| response to cytokine |
| leukocyte tethering or rolling |
| positive regulation of receptor internalization |
| GO Term |
|---|
| clathrin-coated pit |
| external side of plasma membrane |
| perinuclear region of cytoplasm |
| extracellular space |
| plasma membrane |
| cortical cytoskeleton |
| caveola |
| membrane raft |
| GO Term |
|---|
| sialic acid binding |
| transmembrane signaling receptor activity |
| metal ion binding |
| phospholipase binding |
| oligosaccharide binding |
Sequence
MIASQFLSALTLVLLIKESGAWSYNTSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLNSILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLALCYTAACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNIPLVAGLSAAGLSLLTLAPFLLWLRKCLRKAKKFVPASSCQSLESDGSYQKPSYIL
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cell surface interactions at the vascular wall | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:5672 | large intestine cancer | |
| DOID:5679 | retinal disease | |
| DOID:5825 | adult lymphoma | |
| DOID:5844 | myocardial infarction | |
| DOID:5854 | silent myocardial infarction | |
| DOID:6000 | congestive heart failure | |
| DOID:615 | leukopenia | |
| DOID:626 | complement deficiency | |
| DOID:6263 | inflammatory breast carcinoma | |
| DOID:635 | acquired immunodeficiency syndrome |
