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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Acetylcholinesterase
Summary
- UniProt ID
- P22303
- Gene Symbol
-
- ACHE
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P22303
- PubChem
- P22303
- The Human Metabolome Database
- HMDBP00524
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Blood group antigen
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- GPI-anchor
- Neurotransmitter degradation
- Nucleus
- Reference proteome
- Secreted
- Serine esterase
- Signal
- Synapse
- Gene Ontology (GO)
| GO Term |
|---|
| cell adhesion |
| nervous system development |
| synapse assembly |
| receptor internalization |
| positive regulation of cold-induced thermogenesis |
| GO Term |
|---|
| extracellular region |
| basement membrane |
| extracellular space |
| nucleus |
| Golgi apparatus |
| plasma membrane |
| membrane |
| neuromuscular junction |
| synapse |
| synaptic cleft |
Sequence
MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQDRCSDL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 296 | N-linked (GlcNAc...) asparagine | |||
| 381 | N-linked (GlcNAc...) asparagine | |||
| 495 | N-linked (GlcNAc...) asparagine |
|
G83460ZZ
G41247ZX
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Neurotransmitter clearance | Homo sapiens |
| Synthesis of PC | Homo sapiens |
| Synthesis, secretion, and deacylation of Ghrelin | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1168 | familial hyperlipidemia | |
| DOID:11719 | oculopharyngeal muscular dystrophy | |
| DOID:11720 | distal myopathy | |
| DOID:11723 | Duchenne muscular dystrophy | |
| DOID:11724 | limb-girdle muscular dystrophy | |
| DOID:11727 | facioscapulohumeral muscular dystrophy | |
| DOID:11832 | visual epilepsy | |
| DOID:11847 | coronary thrombosis | |
| DOID:11870 | Pick's disease | |
| DOID:1192 | peripheral nervous system neoplasm |
