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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Acetylcholinesterase
Summary
- UniProt ID
- P22303
- Gene Symbol
-
- ACHE
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P22303
- PubChem
- P22303
- The Human Metabolome Database
- HMDBP00524
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Blood group antigen
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- GPI-anchor
- Neurotransmitter degradation
- Nucleus
- Reference proteome
- Secreted
- Serine esterase
- Signal
- Synapse
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of protein secretion |
| choline metabolic process |
| amyloid precursor protein metabolic process |
| acetylcholine catabolic process in synaptic cleft |
| regulation of receptor recycling |
| GO Term |
|---|
| extracellular region |
| basement membrane |
| extracellular space |
| nucleus |
| Golgi apparatus |
| plasma membrane |
| membrane |
| neuromuscular junction |
| synaptic cleft |
| cell surface |
Sequence
MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQDRCSDL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 296 | N-linked (GlcNAc...) asparagine | |||
| 381 | N-linked (GlcNAc...) asparagine | |||
| 495 | N-linked (GlcNAc...) asparagine |
|
G83460ZZ
G41247ZX
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Neurotransmitter clearance | Homo sapiens |
| Synthesis of PC | Homo sapiens |
| Synthesis, secretion, and deacylation of Ghrelin | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1324 | lung cancer | |
| DOID:13375 | temporal arteritis | |
| DOID:13378 | Kawasaki disease | |
| DOID:1824 | status epilepticus | |
| DOID:13481 | thanatophoric dysplasia | |
| DOID:13487 | childhood disintegrative disease | |
| DOID:13515 | tuberous sclerosis | |
| DOID:1352 | paranasal sinus disease | |
| DOID:13548 | secondary Parkinson disease | |
| DOID:13709 | premature ejaculation |
