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MIRAGE
Tyrosine-protein phosphatase non-receptor type 6
Summary
- UniProt ID
- P29351
- Gene Symbol
-
- Hcp
- Hcph
- Ptp1C
- Ptpn6
- Gene ID
- 15170
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Cytoplasm
- Direct protein sequencing
- Disease variant
- Nucleus
- Phosphoprotein
- Protein phosphatase
- Reference proteome
- Repeat
- SH2 domain
- Gene Ontology (GO)
| GO Term |
|---|
| nucleolus |
| cytoplasm |
| cell-cell junction |
| alpha-beta T cell receptor complex |
| nucleoplasm |
| cytosol |
| GO Term |
|---|
| T cell proliferation |
| negative regulation of T cell proliferation |
| regulation of B cell differentiation |
| negative regulation of innate immune response |
Sequence
MVRWFHRDLSGPDAETLLKGRGVPGSFLARPSRKNQGDFSLSVRVDDQVTHIRIQNSGDFYDLYGGEKFATLTELVEYYTQQQGILQDRDGTIIHLKYPLNCSDPTSERWYHGHISGGQAESLLQAKGEPWTFLVRESLSQPGDFVLSVLNDQPKAGPGSPLRVTHIKVMCEGGRYTVGGSETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYVKNQLLGPDENSKTYIASQGCLDATVNDFWQMAWQENTRVIVMTTREVEKGRNKCVPYWPEVGTQRVYGLYSVTNSREHDTAEYKLRTLQISPLDNGDLVREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEIIQSQKGQESEYGNITYPPAVRSAHAKASRTSSKHKEEVYENVHSKSKKEEKVKKQRSADKEKNKGSLKRK
Glycosylation Sites
G41840AI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | Mus musculus |
| CD22 mediated BCR regulation | Mus musculus |
| Costimulation by the CD28 family | Mus musculus |
| GPVI-mediated activation cascade | Mus musculus |
| Interferon gamma signaling | Mus musculus |
| Interleukin receptor SHC signaling | Mus musculus |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | Mus musculus |
| Neutrophil degranulation | Mus musculus |
| PD-1 signaling | Mus musculus |
| PECAM1 interactions | Mus musculus |
