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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Sterol O-acyltransferase 1
Summary
- UniProt ID
- P35610
- Gene Symbol
-
- SOAT1
- ACACT
- ACACT1
- ACAT
- ACAT1
- SOAT
- STAT
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Acyltransferase
- Alternative splicing
- Cholesterol metabolism
- Disulfide bond
- Endoplasmic reticulum
- Phosphoprotein
- Reference proteome
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| membrane |
| endoplasmic reticulum |
| endoplasmic reticulum membrane |
| GO Term |
|---|
| cholesterol binding |
| identical protein binding |
| fatty-acyl-CoA binding |
| sterol O-acyltransferase activity |
| cholesterol O-acyltransferase activity |
Sequence
MVGEEKMSLRNRLSKSRENPEEDEDQRNPAKESLETPSNGRIDIKQLIAKKIKLTAEAEELKPFFMKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSVLEGEKNNHRAKDLRAPPEQGKIFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSLLSYAFGKFPTVVWTWWIMFLSTFSVPYFLFQHWATGYSKSSHPLIRSLFHGFLFMIFQIGVLGFGPTYVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRNPTVRWGYVAMKFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWFFSKRFKSAAMLAVFAVSAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRKKPIWNVLMWTSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYVRPRSWTCRYVF
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 36 |
|
|||
| 38 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| LDL clearance | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:8866 | actinic keratosis | |
| DOID:8893 | psoriasis | |
| DOID:8923 | skin melanoma | |
| DOID:898 | autosomal dominant polycystic kidney disease | |
| DOID:8997 | polycythemia vera | |
| DOID:9065 | leishmaniasis | |
| DOID:9074 | systemic lupus erythematosus | |
| DOID:9080 | macroglobulinemia | |
| DOID:9088 | parapsoriasis | |
| DOID:9119 | acute myeloid leukemia |
