Nicotinamide phosphoribosyltransferase

Summary
UniProt ID
P43490
Gene Symbol
  • NAMPT
  • PBEF
  • PBEF1
Organism
Homo sapiens (human)
External Links
GlyGen
P43490
PubChem
P43490
The Human Metabolome Database
HMDBP08864
The O-GlcNAc Database
P43490
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Biological rhythms
  • Cytokine
  • Cytoplasm
  • Glycosyltransferase
  • Nucleus
  • Phosphoprotein
  • Pyridine nucleotide biosynthesis
  • Reference proteome
  • Secreted
Gene Ontology (GO)
Sequence
MNPAAEAEFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKTENSKLRKVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIELEAAHH
Glycosylation Sites
Displaying 1 entry
Position Description PubMed ID GlyTouCan ID Source
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 3 entries
Pathway Name Organism
BMAL1:CLOCK,NPAS2 activates circadian gene expression Homo sapiens
NPAS4 regulates expression of target genes Homo sapiens
Nicotinamide salvaging Homo sapiens
Disease
Displaying entries 1 - 10 of 269 in total
DO ID Disease Name Source
DOID:0014667 disease of metabolism
DOID:0040085 bacterial sepsis
DOID:0050336 hypophosphatemia
DOID:0050387 nonpapillary renal cell carcinoma
DOID:0050523 adult T-cell leukemia/lymphoma
DOID:0050589 inflammatory bowel disease
DOID:0050590 severe congenital neutropenia
DOID:0050700 cardiomyopathy
DOID:0050747 obsolete lymphoplasmacytic lymphoma
DOID:0050865 tongue squamous cell carcinoma

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024