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Na(+)/H(+) exchange regulatory cofactor NHE-RF1

Summary

UniProt ID

P70441

Gene Symbol

Nherf1
Nherf
Slc9a3r1

Organism

Mus musculus (house mouse)

External Links

GlyGen: P70441
The O-GlcNAc Database: P70441

Annotation

Keyword

Acetylation
Alternative splicing
Cell membrane
Cell projection
Cytoplasm
Phosphoprotein
Reference proteome
Repeat
Wnt signaling pathway

Gene Ontology (GO)

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GO Term
renal sodium ion transport
cilium organization
negative regulation of mitotic cell cycle
establishment of Golgi localization
gamma-aminobutyric acid import
renal absorption
protein localization to plasma membrane
negative regulation of cell motility
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
auditory receptor cell stereocilium organization

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GO Term
extracellular region
cytoplasm
microvillus
endomembrane system
membrane
plasma membrane protein complex
apical plasma membrane
filopodium
brush border membrane
microvillus membrane

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GO Term
signaling receptor binding
molecular adaptor activity
chloride channel regulator activity
protein domain specific binding
PDZ domain binding
beta-2 adrenergic receptor binding
type 2 metabotropic glutamate receptor binding
type 3 metabotropic glutamate receptor binding
myosin II binding
dopamine receptor binding

Annotation information from UniProt.

Sequence

MSADAAAGEPLPRLCCLEKGPNGYGFHLHGEKGKVGQFIRLVEPGSPAEKSGLLAGDRLVEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDERLKKLGVSIREELLRPQEKSEQAEPPAAADTHEAGDQNEAEKSHLRELRPRLCTMKKGPNGYGFNLHSDKSKPGQFIRAVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIKGGGDEAKLLVVDKETDEFFKKCKVIPSQEHLDGPLPEPFSNGEIQKESSREALVEPASESPRPALARSASSDTSEELNSQDSPKRQVSTEPSSTSSSSSDPILDLNISLAVAKERAHQKRSSKRAPQMDWSKKNELFSNL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites