GlyCosmos Portal

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Displaying entries **26 - 50** of **126547** in total

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UniProt ID	Protein Name	Gene Symbol	Organism	Taxonomy ID	Gene Ontology	Gene Ontology ID
P16054	Protein kinase C epsilon type	Prkce Pkce Pkcea	Mus musculus (house mouse)	10090	14-3-3 protein binding ATP binding Golgi membrane MAPK cascade SH3 domain binding T-tubule TRAM-dependent toll-like receptor 4 signaling pathway actin monomer binding cell cycle cell division cell periphery cell-substrate adhesion cellular response to ethanol cellular response to hypoxia cellular response to platelet-derived growth factor stimulus cellular response to prostaglandin E stimulus chemosensory behavior cytoplasm cytosol diacylglycerol-dependent serine/threonine kinase activity diacylglycerol-dependent, calcium-independent serine/threonine kinase activity endoplasmic reticulum enzyme activator activity establishment of localization in cell ethanol binding glutamatergic synapse insulin secretion intermediate filament cytoskeleton intracellular signal transduction lipopolysaccharide-mediated signaling pathway locomotory exploration behavior macrophage activation involved in immune response membrane metal ion binding mitochondrion mucus secretion negative regulation of apoptotic process negative regulation of mitochondrial calcium ion concentration negative regulation of mitochondrial membrane potential negative regulation of protein ubiquitination negative regulation of release of sequestered calcium ion into cytosol neuromuscular junction nucleus perinuclear region of cytoplasm phosphorylation positive regulation of MAPK cascade positive regulation of actin filament polymerization positive regulation of canonical NF-kappaB signal transduction positive regulation of cell-substrate adhesion positive regulation of cellular glucuronidation positive regulation of cytokinesis positive regulation of epithelial cell migration positive regulation of fibroblast migration positive regulation of insulin secretion positive regulation of lipid catabolic process positive regulation of mucus secretion positive regulation of synaptic transmission, GABAergic positive regulation of wound healing presynaptic cytosol presynaptic modulation of chemical synaptic transmission protein kinase binding protein serine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase binding regulation of insulin secretion involved in cellular response to glucose stimulus regulation of lipid metabolic process regulation of peptidyl-tyrosine phosphorylation regulation of release of sequestered calcium ion into cytosol response to morphine signaling receptor activator activity signaling receptor binding synaptic transmission, GABAergic	GO:0000139 GO:0000165 GO:0002281 GO:0003785 GO:0004674 GO:0004697 GO:0004699 GO:0005102 GO:0005524 GO:0005634 GO:0005737 GO:0005739 GO:0005783 GO:0005829 GO:0007049 GO:0007635 GO:0008047 GO:0010634 GO:0010763 GO:0010811 GO:0010917 GO:0016020 GO:0016310 GO:0017124 GO:0019216 GO:0019901 GO:0030073 GO:0030315 GO:0030546 GO:0030838 GO:0031397 GO:0031589 GO:0031594 GO:0031663 GO:0032024 GO:0032230 GO:0032467 GO:0035276 GO:0035556 GO:0035641 GO:0035669 GO:0036120 GO:0043066 GO:0043123 GO:0043278 GO:0043410 GO:0045111 GO:0046872 GO:0048471 GO:0050730 GO:0050996 GO:0051279 GO:0051280 GO:0051301 GO:0051562 GO:0051649 GO:0051932 GO:0061178 GO:0070254 GO:0070257 GO:0071361 GO:0071380 GO:0071456 GO:0071889 GO:0071944 GO:0090303 GO:0098978 GO:0099171 GO:0099523 GO:0106310 GO:0120283 GO:2001031
Q6ZN17	Protein lin-28 homolog B	LIN28B CSDD2	Homo sapiens (human)	9606	RNA 3'-end processing RNA binding RNA destabilization cytoplasm cytosol mRNA binding miRNA catabolic process negative regulation of pre-miRNA processing negative regulation of primary miRNA processing nucleolus nucleoplasm nucleus positive regulation of miRNA catabolic process pre-miRNA processing sequence-specific double-stranded DNA binding zinc ion binding	GO:0003723 GO:0003729 GO:0005634 GO:0005654 GO:0005730 GO:0005737 GO:0005829 GO:0008270 GO:0010587 GO:0031054 GO:0031123 GO:0050779 GO:1990837 GO:2000627 GO:2000632 GO:2000635
Q9UBQ5	Eukaryotic translation initiation factor 3 subunit K	EIF3K EIF3S12	Homo sapiens (human)	9606	RNA binding cytosol eukaryotic 43S preinitiation complex eukaryotic 48S preinitiation complex eukaryotic translation initiation factor 3 complex formation of cytoplasmic translation initiation complex membrane nucleus regulation of translational initiation ribosome binding translation initiation factor activity translational initiation	GO:0001732 GO:0003723 GO:0003743 GO:0005634 GO:0005829 GO:0005852 GO:0006413 GO:0006446 GO:0016020 GO:0016282 GO:0033290 GO:0043022
A0A1P8AM87	WUSCHEL related homeobox 4	WOX4 WUSCHEL related homeobox 4	Arabidopsis thaliana (thale cress)	3702	DNA binding DNA-binding transcription factor activity cell division nucleus phloem or xylem histogenesis procambium histogenesis	GO:0003677 GO:0003700 GO:0005634 GO:0010067 GO:0010087 GO:0051301
Q96JJ6	Junctophilin-4	JPH4 JPHL1 KIAA1831	Homo sapiens (human)	9606	calcium ion transport into cytosol dendritic shaft endoplasmic reticulum membrane junctional membrane complex junctional sarcoplasmic reticulum membrane learning neuromuscular process controlling balance plasma membrane regulation of cytokine production regulation of ryanodine-sensitive calcium-release channel activity regulation of store-operated calcium entry regulation of synaptic plasticity smooth endoplasmic reticulum	GO:0001817 GO:0005789 GO:0005790 GO:0005886 GO:0007612 GO:0014701 GO:0030314 GO:0043198 GO:0048167 GO:0050885 GO:0060314 GO:0060402 GO:2001256
Q9H0K1	Serine/threonine-protein kinase SIK2	SIK2 KIAA0781 QIK SNF1LK2	Homo sapiens (human)	9606	ATP binding cytoplasm endoplasmic reticulum membrane intracellular signal transduction magnesium ion binding nucleus protein autophosphorylation protein phosphorylation protein serine kinase activity protein serine/threonine kinase activity regulation of insulin receptor signaling pathway	GO:0000287 GO:0004674 GO:0005524 GO:0005634 GO:0005737 GO:0005789 GO:0006468 GO:0035556 GO:0046626 GO:0046777 GO:0106310
Q13162	Peroxiredoxin-4	PRDX4	Homo sapiens (human)	9606	I-kappaB phosphorylation cell redox homeostasis cellular response to stress cytosol endoplasmic reticulum extracellular exosome extracellular matrix organization extracellular region ficolin-1-rich granule lumen hydrogen peroxide catabolic process identical protein binding male gonad development molecular adaptor activity molecular sequestering activity negative regulation of male germ cell proliferation nucleus protein maturation by protein folding response to oxidative stress secretory granule lumen spermatogenesis thioredoxin peroxidase activity	GO:0005576 GO:0005634 GO:0005783 GO:0005829 GO:0006979 GO:0007252 GO:0007283 GO:0008379 GO:0008584 GO:0022417 GO:0030198 GO:0033554 GO:0034774 GO:0042744 GO:0042802 GO:0045454 GO:0060090 GO:0070062 GO:0140313 GO:1904813 GO:2000255
Q8BZW8	NHL repeat-containing protein 2	Nhlrc2	Mus musculus (house mouse)	10090	cytosol	GO:0005829
Q920E5	Farnesyl pyrophosphate synthase	Fdps	Mus musculus (house mouse)	10090	cholesterol biosynthetic process cytoplasm cytosol dimethylallyltranstransferase activity farnesyl diphosphate biosynthetic process geranyl diphosphate biosynthetic process geranyltranstransferase activity metal ion binding mitochondrial matrix mitochondrion nucleoplasm peroxisome positive regulation of cell growth involved in cardiac muscle cell development positive regulation of cholesterol biosynthetic process	GO:0004161 GO:0004337 GO:0005654 GO:0005737 GO:0005739 GO:0005759 GO:0005777 GO:0005829 GO:0006695 GO:0033384 GO:0045337 GO:0045542 GO:0046872 GO:0061051
G5E8J8	Widely-interspaced zinc finger motifs	Wiz	Mus musculus (house mouse)	10090	DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding metal ion binding nucleus	GO:0000978 GO:0000981 GO:0005634 GO:0046872
O35147	Bcl2-associated agonist of cell death	Bad	Rattus norvegicus (Norway rat)	10116	14-3-3 protein binding ADP metabolic process ATP metabolic process BAD-BCL-2 complex activation of cysteine-type endopeptidase activity involved in apoptotic process apoptotic process apoptotic signaling pathway cellular response to chromate cellular response to hypoxia cellular response to lipid cellular response to mechanical stimulus cellular response to nicotine cerebral cortex development cysteine-type endopeptidase activator activity involved in apoptotic process cytokine-mediated signaling pathway cytoplasm cytosol epithelial cell proliferation extrinsic apoptotic signaling pathway in absence of ligand extrinsic apoptotic signaling pathway via death domain receptors extrinsic apoptotic signaling pathway glucose catabolic process glucose homeostasis intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway lipid binding mitochondrial outer membrane mitochondrion phospholipid binding pore complex assembly positive regulation of B cell differentiation positive regulation of T cell differentiation positive regulation of apoptotic process positive regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of epithelial cell proliferation positive regulation of glucokinase activity positive regulation of granulosa cell apoptotic process positive regulation of insulin secretion involved in cellular response to glucose stimulus positive regulation of insulin secretion positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress positive regulation of mitochondrial membrane potential positive regulation of proteolysis positive regulation of release of cytochrome c from mitochondria positive regulation of type B pancreatic cell development protein kinase B binding protein kinase binding protein phosphatase 2B binding protein phosphatase binding regulation of apoptotic process regulation of mitochondrial membrane permeability release of cytochrome c from mitochondria response to amino acid response to benzene response to calcium ion response to estradiol response to ethanol response to glucocorticoid response to glucose response to hormone response to hydrogen peroxide response to hypoxia response to oleic acid response to organic cyclic compound response to organic substance response to progesterone response to testosterone response to xenobiotic stimulus spermatogenesis type B pancreatic cell proliferation	GO:0001666 GO:0001836 GO:0005543 GO:0005737 GO:0005739 GO:0005741 GO:0005829 GO:0006007 GO:0006915 GO:0006919 GO:0007283 GO:0008289 GO:0008625 GO:0008630 GO:0008656 GO:0009410 GO:0009725 GO:0009749 GO:0010033 GO:0010918 GO:0014070 GO:0019221 GO:0019901 GO:0019903 GO:0021987 GO:0030346 GO:0032024 GO:0032355 GO:0032570 GO:0033133 GO:0033574 GO:0034201 GO:0035774 GO:0042542 GO:0042593 GO:0042981 GO:0043065 GO:0043200 GO:0043280 GO:0043422 GO:0044342 GO:0045471 GO:0045579 GO:0045582 GO:0045862 GO:0046031 GO:0046034 GO:0046902 GO:0046931 GO:0050673 GO:0050679 GO:0051384 GO:0051592 GO:0071247 GO:0071260 GO:0071316 GO:0071396 GO:0071456 GO:0071889 GO:0090200 GO:0097138 GO:0097190 GO:0097191 GO:0097192 GO:0097193 GO:1901423 GO:1902220 GO:1904710 GO:2000078
Q66PJ3	ADP-ribosylation factor-like protein 6-interacting protein 4	ARL6IP4	Homo sapiens (human)	9606	RNA binding RNA splicing mRNA processing nuclear speck nucleolus nucleus	GO:0003723 GO:0005634 GO:0005730 GO:0006397 GO:0008380 GO:0016607
Q9WV31	Activity-regulated cytoskeleton-associated protein	Arc	Mus musculus (house mouse)	10090	acrosomal vesicle actin binding actin cytoskeleton anterior/posterior pattern specification cell cortex cell migration clathrin-coated vesicle membrane cytoplasm cytoskeleton organization cytoskeleton dendrite dendritic spine early endosome membrane endocytosis endoderm development extracellular vesicle glutamatergic synapse learning long-term memory mRNA binding mRNA transport membrane raft modulation of chemical synaptic transmission neuronal ribonucleoprotein granule plasma membrane postsynaptic density membrane postsynaptic endosome protein homooligomerization regulation of cell morphogenesis regulation of dendritic spine morphogenesis regulation of long-term synaptic depression regulation of long-term synaptic potentiation regulation of neuronal synaptic plasticity regulation of postsynaptic neurotransmitter receptor internalization response to ethanol response to morphine vesicle-mediated intercellular transport	GO:0001669 GO:0003729 GO:0003779 GO:0005737 GO:0005856 GO:0005886 GO:0005938 GO:0006897 GO:0007010 GO:0007492 GO:0007612 GO:0007616 GO:0009952 GO:0015629 GO:0016477 GO:0022604 GO:0030425 GO:0030665 GO:0031901 GO:0043197 GO:0043278 GO:0045121 GO:0045471 GO:0048168 GO:0050804 GO:0051028 GO:0051260 GO:0061001 GO:0071598 GO:0098839 GO:0098845 GO:0098978 GO:0099149 GO:0110077 GO:1900271 GO:1900452 GO:1903561
G3X8R1	Kaptin	Kptn	Mus musculus (house mouse)	10090	KICSTOR complex actin filament binding actin filament organization cellular response to amino acid starvation cellular response to glucose starvation filamentous actin lamellipodium negative regulation of TORC1 signaling postsynaptic actin cytoskeleton protein localization to lysosome	GO:0007015 GO:0030027 GO:0031941 GO:0034198 GO:0042149 GO:0051015 GO:0061462 GO:0098871 GO:0140007 GO:1904262
Q2I5R9	Peptidyl-prolyl cis-trans isomerase	Pin1	Trypanosoma cruzi	5693	cytosol nucleus peptidyl-prolyl cis-trans isomerase activity	GO:0003755 GO:0005634 GO:0005829
Q8NBR9	Uncharacterized protein NDUFV1-DT	NDUFV1-DT C11orf72	Homo sapiens (human)	9606
V5BE86	Eukaryotic translation initiation factor 3 subunit I	TCDM_07590	Trypanosoma cruzi Dm28c	1416333	RNA binding eukaryotic 43S preinitiation complex eukaryotic 48S preinitiation complex eukaryotic translation initiation factor 3 complex, eIF3m formation of cytoplasmic translation initiation complex translation initiation factor activity	GO:0001732 GO:0003723 GO:0003743 GO:0016282 GO:0033290 GO:0071541
V5BC94	Uncharacterized protein	TCDM_00356	Trypanosoma cruzi Dm28c	1416333
V5BK30	Multidrug resistance protein E	TCDM_04857	Trypanosoma cruzi Dm28c	1416333	ABC-type transporter activity ATP binding ATP hydrolysis activity membrane	GO:0005524 GO:0016020 GO:0016887 GO:0140359
A4D1E1	Zinc finger protein 804B	ZNF804B	Homo sapiens (human)	9606	metal ion binding nucleus	GO:0005634 GO:0046872
Q9BT22	Chitobiosyldiphosphodolichol beta-mannosyltransferase	ALG1 HMAT1 HMT1	Homo sapiens (human)	9606	chitobiosyldiphosphodolichol beta-mannosyltransferase activity dolichol-linked oligosaccharide biosynthetic process endoplasmic reticulum membrane endoplasmic reticulum mannosyltransferase activity membrane protein glycosylation	GO:0000030 GO:0004578 GO:0005783 GO:0005789 GO:0006486 GO:0006488 GO:0016020
Q9EP97	Sentrin-specific protease 3	Senp3 Smt3ip Smt3ip1	Mus musculus (house mouse)	10090	MLL1 complex cysteine-type deubiquitinase activity cytoplasm deSUMOylase activity negative regulation of double-strand break repair via homologous recombination nucleolus nucleus protein desumoylation protein metabolic process proteolysis	GO:0004843 GO:0005634 GO:0005730 GO:0005737 GO:0006508 GO:0016926 GO:0016929 GO:0019538 GO:0071339 GO:2000042
Q99PU7	Ubiquitin carboxyl-terminal hydrolase BAP1	Bap1 Kiaa0272	Mus musculus (house mouse)	10090	PR-DUB complex cell population proliferation chromatin DNA binding chromatin binding common myeloid progenitor cell proliferation cysteine-type deubiquitinase activity cytoplasm cytosol erythrocyte differentiation erythrocyte maturation gene expression granulocyte differentiation hematopoietic stem cell homeostasis histone H2A deubiquitinase activity in utero embryonic development leukocyte proliferation macrophage homeostasis mitotic cell cycle monoubiquitinated protein deubiquitination myeloid cell apoptotic process negative regulation of DNA-templated transcription negative regulation of cell population proliferation neuron cellular homeostasis neutrophil differentiation nucleate erythrocyte differentiation nucleoplasm nucleus platelet morphogenesis protein K48-linked deubiquitination protein deubiquitination regulation of cell cycle regulation of cell growth regulation of cytokine production involved in inflammatory response regulation of inflammatory response response to inorganic substance thrombocyte differentiation tissue homeostasis ubiquitin-dependent protein catabolic process	GO:0000278 GO:0001558 GO:0001701 GO:0001894 GO:0002574 GO:0003682 GO:0004843 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0006511 GO:0008283 GO:0008285 GO:0010035 GO:0010467 GO:0016579 GO:0030218 GO:0030223 GO:0030851 GO:0031490 GO:0033028 GO:0035517 GO:0035520 GO:0035726 GO:0036344 GO:0043249 GO:0043363 GO:0045892 GO:0050727 GO:0051726 GO:0061484 GO:0061519 GO:0070050 GO:0070661 GO:0071108 GO:0140950 GO:1900015
Q4DTI4	Dynein heavy chain, putative (Fragment)	Tc00.1047053507053.209	Trypanosoma cruzi strain CL Brener	353153	9+2 motile cilium ATP binding ATP hydrolysis activity axoneme cilium assembly cilium movement involved in cell motility cytoplasmic dynein complex dynein intermediate chain binding dynein light intermediate chain binding intraciliary retrograde transport microtubule minus-end-directed microtubule motor activity	GO:0005524 GO:0005868 GO:0005874 GO:0005930 GO:0008569 GO:0016887 GO:0035721 GO:0045505 GO:0051959 GO:0060271 GO:0060294 GO:0097729
V5B664	Unc104-like kinesin	TCDM_02439	Trypanosoma cruzi Dm28c	1416333

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